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31篇 您的检索式:作者名="Prokhorova"
    题名 作者 年代 出处 被引量
1Ugi反应合成4-甲基-1,2,3-噻二唑化合物及其抗烟草花叶病毒活性(英文)显示文摘为了寻找更多高活性化合物和进行先导结构的衍生,利用Ugi反应设计合成了18个4-甲基-1,2,3-噻二唑新化合物(I-1~I-18),其结构均经核磁共振氢谱、红外光谱和高分辨质谱的表征和确认。杀菌、抗病毒以及诱导活性的筛选结果表明:目标化合物I-3和I-11抗烟草花叶病毒(TMV)的半叶法活性高于对照药剂病毒唑,I-6的保护活性和钝化活性高于病毒唑,I-12的治疗活性高于病毒唑,I-16的诱导活性高于对照药剂噻酰菌胺;氟原子的引入有利于保持和提高新化合物的抗病毒活性,4-甲基-1,2,3-噻二唑和氟原子是新化合物抗病毒的重要活性亚结构单元。Ugi反应是新农药创制中先导优化的绿色手段。付一峰 左翔 范志金 米娜 郑琴香 黄云 王唤 黄杰 BELSKAYA N.P. BAKULEV V.A. MORZHERIN Yu.Yu. PROKHOROVA P.E. 2010农药学学报2010,12,4:2
2Low-dose melphalan-induced shift in the production of TH2-type cytokine to a TH1-type cycokine in mice bearing a large mopc-315 tumor显示文摘 Prokhorova A Mokyr MB 1994Cancer Immunol Immunother1994,39,2:1
3The BRCA1/ BARD1 heterodimer modulates ran-dependent mitotic spindle assembly显示文摘Joukov V Groen A Prokhorova T 2006Cell2006,12,27:1
4Functional characterization of interstitial macrophages and subpopulation of alveolar maerophages from rat lung显示文摘 Lavnikova N Laskin D L 1994J Leukocyte Boil1994,55,2:1
5A new fluorogenic calix arene N-dansylcarboxamide in the cone conformation for selective optical recognition of mercury(Ⅱ) 显示文摘DINAKE P PROKHOROVA P E TALANOV V S 2010Tetrahedron Letters2010,51,38:1
6The BRCA1/BARD1 heterodimer modulates ran-dependent mitotic spindle assembly显示文摘 GROEN A C PROKHOROVA T 2006Cell2006,127,3:1
7A new fluorogenic calix arene N-dansylcarboxamide in the cone conformation for selective optical recognition of mercury(II)显示文摘DINAKE P PROKHOROVA P E TALANOV V S 2010Tetrahedron Letters2010,51,38:1
8Sequential MCM/PI subcomplex assembly is required to form a heterohexamer with replication licensing activity显示文摘Prokhorova TA Blow JJ 2000J Biol Chem2000,275,4:1
9The BRCA1/BARD1 het-erodimer modulates ran-dependent mitotic spindle assembly显示文摘Joukov V Groen A C Prokhorova T 2006Cell2006,127,3:1
10Low-dose melphalaninduced shift in the production of a Th2-type cytokine to a Th1- type cytokine in mice bearing a large MOPC-375 tumor显示文摘Gorelik L Prokhorova A Mokyr M B 1994Cancer Immunol Immunother1994,39,2:1
11Solid-state modeling of the terahertz spectrum of the high explosive HMX 显示文摘Allis D G Prokhorova D A Korter T M 2006Journal of Physical Chemistry A2006,110,5:1
12Functional characterization of interstitial macrophages and subpopulation of alveolar macrophages from rat lung显示文摘Prokhorova S Lavnikova N Laskin DL 1994J Leukocyte Boil1994,55,:1
13Stable isotope labeling by amino acids in cell culture (SILAC) and quantitative comparison of the mem- brane proteomes of self-renewing and differentiating human embryonic stem eells显示文摘Prokhorova T A 2009Mol Cell Proteomics2009,8,:1
14Low-dose melphalan-induced shift in the production of a Th2-type cytokine to a Th1-type cytokine in mice bearing a large MOPC-315tumor显示文摘Gorelik L Prokhorova A Mokyr M B 1994Cancer Immunol Immunother1994,39,2:1
15Chiral ananlysis of pharmaceuticals by capillary electrophoresis using antibiotics as chiral selectors 显示文摘Prokhorova AF Shapovalova EN Shpigun OA 2010J Pharm Biomed Anal2010,53,5:1
16The estimation of the ef- ficacy of galvanic peloid therapy for the treatment of the children with chronic post-traumatic knee-joint synovitis following arthroscopy显示文摘Vybornov DIu Prokhorova ES Podgornaia OV 2012Vopr Kurortol Fizioter Lech Fiz Kult2012,8,5:1
17The BRCA1/ BARD1 heterodimer modulates ran-dependent mitotic spindle assembly显示文摘Joukov V Groen AC Prokhorova T 2006Cell2006,127,3:1
18Low-dose melphalan-induced shift in the production of a Th2-type cytokine to a Th1-type cytokine in mice bearing a large MOPC-315 tumor显示文摘Gorelik L Prokhorova A Mokyr MB 1994Cancer Immunol Immunother1994,39,2:1
19Evolution of ordered films of copper phthalocyanine according to EPR data显示文摘Boguslavskii E G Prokhorova S A Nadolinnyi V A 2005Journal of Structural Chemistry2005,46,6:1
20Interaction of basic refractories with converter slag 显示文摘Prokhorova I Y Novikova 0 V 1980Refract Ind Ceram1980,21,6:1
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