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| 1 | Scale dependence of direct shear tests显示文摘Direct shear test has been widely used to measure the shear strength of soils and other particulate materials in industry because of its simplicity. However, the results can be dependent on the specimen size. The ASTM (American Society for Testing and Materials) publications suggest that for testing soils the shear box should be at least ten times the diameter of the largest particle and the height of the box should be no more than half of its diameter. These guidelines are empirically based. A series of two-dimensional numerical direct shear tests are performed to investigate this scaling effect. By analyzing the bulk friction, particle translation and rotation, percentage of sliding, average volume (area) and shear strain and the evolution of the shear band, we find that the traditional guidelines for direct shear tests are questionable. Scaling dependency of bulk friction on the property of granular materials is clearly present. Our current analysis points out that the scaling effects can vary significantly depending on the particle properties other than their sizes. Of all the parameters we observed, particle rotation appears to have a decisive correlation with the bulk friction. Formation of a shear band is universal. As the shearing progresses, particle rotation begins to concentrate near the shear plane. By defining the width of a shear band as the standard deviation of the distribution of translational gradient or the standard deviation of the distribution of particle rotation, quantitative evolutions of shear band are presented. Both measures of the shear band width dropped rapidly during pre-failure stage. After peak stress both measures begin to approach steady state as the bulk friction stabilizes to the residual stage. These observations suggest that structure formation inside the shear band controls the scaling effect. | ZHOU Qiang SHEN Hayley H HELENBROOK Brian T ZHANG HongWu | 2009 | Chinese Science Bulletin2009，54，23： | 6 |
| 2 | Correlation of mechanical properties in bulk metallic glasses with ^(27)Al NMR characteristics显示文摘We report 27Al NMR and magnetic susceptibility measurements of Zr and ZrHf-based bulk metallic glasses (BMGs). 27Al NMR Knight shift shows that there exists a clear correlation between the local electronic properties at Al sites and mechanical properties. In addition,magnetic susceptibility measurements also provide clues on the influence of the electronic states,especially the strong influence of d-orbital characteristics on the mechanical properties of toughness and hardness. | SANDOR Magdalena T KECSKES Laszlo J HE Qiang XU Jian WU Yue | 2011 | Chinese Science Bulletin2011，56，36： | 2 |
| 3 | Prostate volume does not provide additional predictive value to prostate health index for prostate cancer or clinically significant prostate cancer:results from a multicenter study in China显示文摘To evaluate whether prostate volume(PV)would provide additional predictive utility to the prostate health index(phi)for predicting prostate cancer(PCa)or clinically significant prostate cancer,we designed a prospective,observational multicenter study in two prostate biopsy cohorts.Cohort 1 included 595 patients from three medical centers from 2012 to 2013,and Cohort 2 included 1025 patients from four medical centers from 2013 to 2014.Area under the receiver operating characteristic curves(AUC)and logistic regression models were used to evaluate the predictive performance of PV-based derivatives and models.Linear regression analysis showed that both total prostate-specific antigen(tPSA)and free PSA(fPSA)were significantly correlated with PV(all P<0.05).[-2]proPSA(p2PSA)was significantly correlated with PV in Cohort 2(P<0.001)but not in Cohort 1(P=0.309),while no significant association was observed between phi and PV.When combining phi with PV,phi density(PHID)and another phi derivative(PHIV,calculated as phi/PV°5)did not outperform phi for predicting PCa or clinically significant PCa in either Cohort 1 or Cohort 2.Logistic regression analysis also showed that phi and PV were independent predictors for both PCa and clinically significant PCa(all P<0.05);however,PV did not provide additional predictive value to phi when combining these derivatives in a regression model(all models vs phi were not statistically significant,all P>0.05).In conclusion,PV-based derivatives(both PHIV and PHID)and models incorporating PV did not improve the predictive abilities of phi for either PCa or clinically significant PCa. | Da Huang Yi-Shuo Wu Ding-Wei Ye Jun Qi Fang Liu Brian T Helfand Siqun L Zheng Qiang Ding Dan-Feng Xu Rong Na Jian-Feng Xu Ying-Hao Sun | 2020 | Asian Journal of Andrology2020，22，5： | 2 |
| 4 | Use of a rapid mistach PCR method to dectect gyrA and part C mutations in ciprofloxacinresistant clinical isolates of Escherichia coli显示文摘 | Qiang YZ Qin T Fu W | 2002 | J Antimicrob Chemother2002，49，3： | 1 |
| 5 | Compact optical temporal differentiator based on silicon microring resonator显示文摘 | Liu F F Wang T Qiang L Ye T Zhang Z Qiu M Su Y | | 0，，20： | 1 |
| 6 | Variations of stomatal density and carbon isotope values of Picea crassifolia at different elevations in the Qilian mountains 显示文摘 | QIANG W Y WANG X N CHEN T | 2003 | Trees2003，17，3： | 1 |
| 7 | The Closed-loop Supply Chain Network with Competition, Distribution Channel Investment, and Uncertainties显示文摘 | Qiang Q Ke K Anderson T | 2013 | Omega2013，41，： | 1 |
| 8 | The closed-loop supply chain network with competition,distribution channel investment,and uncertainties显示文摘 | Qiang Q Ke K Anderson T | 2013 | Omega2013，41，2： | 1 |
| 9 | Study on preparation, characteriza- tion and sizing performance of modified collagen surface sizing agent显示文摘 | Wang X C Hao X L Qiang T T | 2014 | Bio Resources2014，9，1： | 1 |
| 10 | Climate changes and their impacts on water resources in the arid regions: a case study of the Tarim River basin, China显示文摘 | QIANG Z CHONG Y X HUI T | 2010 | Stochastic Environmental Research and Risk Assessment2010，24，3： | 1 |
| 11 | Preparation of microencapsulated ammonium polypbosphate with carbon source-and blowing agent-containing shell and its flame retardance in polypropylene 显示文摘 | ZHENG Z QIANG L YANG T | 2014 | Journal of Polymer Research2014，21，5： | 1 |
| 12 | The impact of time based manufacturing practices on mass customization and value to customer显示文摘 | Qiang Tu Mark Vonderembse A Ragu Nathan T S | 2001 | Journal of Operations Management2001，19，： | 1 |
| 13 | Knowledge-Based System for Railway Scheduling显示文摘 | QIANG T W Hau H Y | 1998 | Data & Knowledge Engineering1998，27，： | 1 |
| 14 | The effect of pea fiber and potato pulp on thermal property, surface tension, and hydrophilicity of extruded starch thermoplastics 显示文摘 | ZHANG Yachuan MICHAEL T LIU Qiang | 2011 | CarbohydrPolym2011，86，： | 1 |
| 15 | Novel of transformation of tannery waste to environmently friendly formaldehyde scavenger 显示文摘 | Wang X C Ren L F Qiang T T | 2009 | Environmental Progress Sustainble Energy2009，28，2： | 1 |
| 16 | Life cycle assessment on polylactide-based wood plastic composites toughened with polyhydroxyalkanoates 显示文摘 | QIANG T YU D M ZHANG A J | 2014 | Journal of Cleaner Production2014，66，： | 1 |
| 17 | PRIMA-I selectively induces global DNA demethylation in p53 mutant-type thyroid cancer cells 显示文摘 | Qiang W Jin T Yang Q | 2014 | J Biomed Nanoteehnol2014，10，7： | 1 |
| 18 | Genome-wide association analysis reveals regulation of at-risk loci by DNA methylation in prostate cancer显示文摘Epigenetic changes are potentially important for the ontogeny and progression of tumors but are not usually studied because of the complexity of analyzing transcript regulation resulting from epigenetic alterations.Prostate cancer(PCa)is characterized by variable clinical manifestations and frequently unpredictable outcomes.We performed an expression quantitative trait loci(eQTL)analysis to identify the genomic regions that regulate gene expression in PCa and identified a relationship between DNA methylation and clinical information.Using multi-level information published in The Cancer Genome Atlas,we performed eQTL-based analyses on DNA methylation and gene expression.To better interpret these data,we correlated loci and clinical indexes to identify the important loci for both PCa development and progression.Our data demonstrated that although only a small proportion of genes are regulated via DNA methylation in PCa,these genes are enriched in important cancer-related groups.In addition,single nucleotide polymorphism analysis identified the locations of CpG sites and genes within at-risk loci,including the 19q13.2-q13.43 and 16q22.2-q23.1 loci.Further,an epigenetic association study of clinical indexes detected risk loci and pyrosequencing for site validation.Although DNA methylation-regulated genes across PCa samples are a small proportion,the associated genes play important roles in PCa carcinogenesis. | Qiang Liu Gang Liu Darryl T Martin Yu-Tong Xing Robert M Weiss Jun Qi Jian Kang | 2021 | Asian Journal of Andrology2021，23，5： | 1 |
| 19 | Knowledge-based system for railway scheduling显示文摘 | Qiang T W Hau H Y | 1998 | Data & Knowledge Engineering1998，27，： | 1 |
| 20 | Multiple expansions of C4 plant biomass in East Asia since 7 Ma coupled with strengthened monsoon circulation 显示文摘 | An Z S Huang Y S Liu W G Guo Z T Clemens S Li L Prell W Ning Y F Cai Y J Zhou W J Lin B H Zhang Q L Cao Y N Qiang X K Chang H Wu Z K | 2005 | Geology2005，33，9： | 1 |
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