|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Efficacy of peroral endoscopic myotomy vs other achalasia treatments in improving esophageal function显示文摘AIM: To assess and compare the esophageal function after peroral endoscopic myotomy(POEM) vs other conventional treatments in achalasia.METHODS: Chart review of all achalasia patients who underwent POEM, laparoscopic Heller myotomy(LHM) or pneumatic dilation(PD) at our institution between January 2012 and March 2015 was performed. Patient demographics, type of achalasia, prior treatments, pre- and post-treatment timed barium swallow(TBE) and high-resolution esophageal manometry(HREM) findings were compared between the three treatment groups. Patients who had both pre- and 2 mo posttreatment TBE or HREM were included in the final analysis. TBE parameters compared were barium column height, width and volume of barium remaining at 1 and 5 min. HREM parameters compared were basal lower esophageal sphincter(LES) pressures and LES-integrated relaxation pressures(IRP). Data are presented as mean ± SD, median [25th, 75 th percentiles] or frequency(percent). Analysis of variance, KruskalWallis test, Pearsons χ~2 test and Fishers Exact tests were used for analysis.RESULTS: A total of 200 achalasia patients were included of which 36 underwent POEM, 22 underwent PD and 142 underwent LHM. POEM patients were older(55.4 ± 16.8 years vs 46.5 ± 15.7 years, P = 0.013) and had higher BMI than LHM(29.1 ± 5.9 kg/m^2 vs 26 ± 5.1 kg/m^2, P = 0.012). More number of patients in POEM and PD groups had undergone prior treatments compared to LHM group(72.2% vs 68.2% vs 44.3% respectively, P = 0.003). At 2 mo post-treatment, all TBE parameters including barium column height, width and volume remaining at 1 and 5 min improved significantly in all three treatment groups(P = 0.01 to P < 0.001) except the column height at 1 min in PD group(P = 0.11). At 2 mo post-treatment, there was significant improvement in basal LES pressure and LES-IRP in both LHM(40.5 mm Hg vs 14.5 mm Hg and 24 mm Hg vs 7.1 mm Hg respectively, P < 0.001) and POEM groups(38.7 mm Hg vs 11.4 mm Hg and 23.6 mm Hg vs 6.6 mm Hg respectively, P < 0.001). However, when the efficacy of three treatments were compared to each other in terms of improvement in TBE or HREM parameters at 2 mo, there was no significant difference(P > 0.05).CONCLUSION: POEM, PD and LHM were all effective in improving esophageal function in achalasia at shortterm. There was no difference in efficacy between the three treatments. | Madhusudhan R Sanaka Umar Hayat Prashanthi N Thota Ramprasad Jegadeesan Monica Ray Scott L Gabbard Neha Wadhwa Rocio Lopez Mark E Baker Sudish Murthy Siva Raja | 2016 | World Journal of Gastroenterology2016，22，20： | 7 |
| 2 | An ethnobotanical survey of medicinal plants used by ethnic people in West and South district of Tripura, India显示文摘An ethno-medicinal investigation was conducted to highlights the traditional knowledge of medicinal plants being used by the tribe in West and South district of Tripura. This paper provides information about the different uses of plants used in their primary health care system. Tripura is a small north-eastern state of India and also a part of both Himalayan and Indo-Burma biodiversity region. It is a goldmine of medicinal plants and use of different plants in tribal traditional heath care systems has long history. Nineteen different tribes in Tripura, depend on natural resources at a great extent. This paper documented 113 medicinal plant species from 56 families along with their botanical name, local name, family name, habit, medicinal parts used, and traditional usage of application. The dominant families are Euphorbiaceae (7 species), Apocynaceae (6 species), Fabaceae and Rubiaceae (5 species each), Caesalpiniaceae, Asteraceae, Liliaceae and Verbenaceae (4 species each), Combretaceae, Labiatae, Malvaceae, Rutaceae and Zingiberaceae (3 species each). Tribes of Tripura have rich traditional knowledge on plant based medicine. Different parts of the plants in crude form/plant extracts/decoctions/infusion or pastes are employed in diverse veterinary and human diseases by the tribe's of Tripura in daily life. | Saikat Sen Raja Chakraborty Biplab De N Devanna | 2011 | Journal of Forestry Research2011，22，3： | 5 |
| 3 | 印度药用植物Meyna spinosa Roxb.叶中的总酚、总黄酮含量及抗氧化作用(英文)显示文摘AIM: The objective of the present study was to determine the total phenolic and total flavonoid contents, and to evaluate the antioxidant potential of different leaf extracts of Meyna spinosa Roxb. ex Link, a traditional medicinal plant of India. METHODS: Free radical scavenging and antioxidant potential of the methanol, ethyl acetate, and petroleum ether extracts of Meyna spinosa leaves were investigated using several in vitro and ex vivo assays, including the 2, 2-diphenyl-picrylhydrazyl radical scavenging, superoxide anion scavenging, hydroxyl radical scavenging, nitric oxide radical scavenging, hydrogen peroxide scavenging activity, metal chelating assay, and reducing power ability method. Total antioxidant activity of the extracts was estimated by the ferric thiocyanate method. Inhibition assay of lipid peroxidation and oxidative hemolysis were also performed to confirm the protective effect of the extracts. Total phenolic and total flavonoid contents of the extracts were estimated using standard chemical assay procedures. RESULTS: Methanol extracts showed the highest polyphenolic content and possessed the better antioxidant activity than the other two extracts. Total phenolic and total flavonoid contents in the methanol extract were (90.08 ± 0.44) mg gallic acid equivalents/g and (58.50 ± 0.09) mg quercetin equivalents/g, respectively. The IC 50 of the methanol extract in the DPPH , superoxide anion, hydroxyl radical, nitric oxide radical, hydrogen peroxide scavenging activity and metal chelating assays were (16.4 ± 0.41), (35.9 ± 0.19), (24.1 ± 0.33), (23.7 ± 0.09), (126.8 ± 2.92), and (117.2 ± 1.01) μg·mL-1 , respectively. The methanol extract showed potent reducing power ability, total antioxidant activity, and significantly inhibit lipid peroxidation and oxidative hemolysis which was similar to that of standards. CONCLUSION: The results indicated a direct correlation between the antioxidant activity and the polyphenolic content of the extracts, which may the foremost contributors to the antioxidant activity of the plant. The present study confirmed that the methanol extract of Meyna spinosa leaves is a potential source of natural antioxidants. | Saikat Sen Biplab De N Devanna Raja Chakraborty | 2013 | 中国天然药物2013，11，2： | 2 |
| 4 | Optimization techniques for machi-ning operations:a retrospective research based on various mathematical models显示文摘 | RAJA S B BASKAR N | | 0，，9： | 1 |
| 5 | Synthesis, chemical characterization, DNA binding, antioxidant, antibacterial, and antifungal activities of ferrocence incorporated selenoureas 显示文摘 | RAJA A H AMIN B MUHAMMAD N T | 2014 | J Biochem Mol Toxico12014，28，2： | 1 |
| 6 | Identification polypeptide biomarkers of porcine skin gelatin by two-dimensional electrophoresis显示文摘 | Aina M A Amin I Raja Mohd Hafidz R N | | 0，，03： | 1 |
| 7 | Synthesis, characterization and in vitro pharmacological evaluation of new water soluble Ni( Ⅱ ) complexes of 4N-substituted thiosemicarbazones of 2-oxo-l,2- dihydroquinoline-3-carbaldehyde显示文摘 | RAMACHANDRAN E RAJA D S BHUVANESH N S P | 2013 | Eur J Med Chem2013，64，： | 1 |
| 8 | Treatment of acute postoperative pain显示文摘 | Wu C L Raja S N | 2011 | The Lancet2011，377，9784： | 1 |
| 9 | Perspectives on deficit irrigation显示文摘 | English M Raja S N | 1996 | Agriculrural Water Management1996，32，： | 1 |
| 10 | Perspectives on deficit irrigation 显示文摘 | English M Raja S N | 1996 | Ag- riculture Water Management1996，32，： | 1 |
| 11 | Faultcurrent contribution from synchronous machine andinverter based distributed generators显示文摘 | NATTHAPHOB N GERALD T H RAJA A | 2007 | IEEE Trans onPower Delivery2007，22，1： | 1 |
| 12 | Chaperone-dependent gene expression of organic solvent-tolerant lipase from Pseudomonas aeruginosa strain S5显示文摘 | Syarul N B Raja N Z R A R Mahiran B | 2010 | Process Biochemistry2010，45，3： | 1 |
| 13 | Perspectives on deficit irrigation显示文摘 | English M Raja S N | 1996 | Agricultural Water Management1996，，32： | 1 |
| 14 | Biodegradation of hydrocarbons in soil by microbial consortium显示文摘 | FARINAZLEEN M G RAJA N Z A R ABU B S | 2004 | International Biodeterioration & Biodegradation2004，54，： | 1 |
| 15 | Thalidomide and immunomodulatory derivalives augment natural killer cell cytotoxicity in multiple myeloma显示文摘 | Davies FE Raja N Hideshima T | 2001 | Blood2001，98，1： | 1 |
| 16 | Laser-induced breakdown speetroseopy analysis of lunar simulants under high vacuum conditions显示文摘 | ANTONY J K VASA N J SRIDHAR RAJA V L N | 2010 | TENCON2010，，4： | 1 |
| 17 | Detection identifica- tion and incidence of Chrysanthemum B carlavirus in chrysan- themum in India 显示文摘 | VERMA N SHARMA A RAJA R | 2003 | Crop Protection2003，22，： | 1 |
| 18 | Relative contribution of core and skin temperatures to thermal comfort in humans 显示文摘 | Bulcao C F Frank S M Raja S N Tran K M Goldstein D S | 2000 | Journal of Thermal Biology2000，25，12： | 1 |
| 19 | Wide viewing angle and fast responding TN LCD 显示文摘 | Chandrasekhar S Raja Krishna V N S Prasad S | 2004 | Molecular Crystals and Liquid Crystals2004，410，1： | 1 |
| 20 | Speed estimation of an induction motot using Elman neural network 显示文摘 | Raja S Toqeer N Suha Bayindir | 2003 | Neurocomputing2003，55，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员