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| 1 | Watch and wait approach in rectal cancer:Current controversies and future directions显示文摘According to the main international clinical guidelines,the recommended treatment for locally-advanced rectal cancer is neoadjuvant chemoradiotherapy followed by surgery.However,doubts have been raised about the appropriate definition of clinical complete response(cCR)after neoadjuvant therapy and the role of surgery in patients who achieve a cCR.Surgical resection is associated with significant morbidity and decreased quality of life(QoL),which is especially relevant given the favourable prognosis in this patient subset. Accordingly, therehas been a growing interest in alternative approaches with less morbidity,including the organ-preserving watch and wait strategy, in which surgery isomitted in patients who have achieved a cCR. These patients are managed with aspecific follow-up protocol to ensure adequate cancer control, including the earlyidentification of recurrent disease. However, there are several open questionsabout this strategy, including patient selection, the clinical and radiologicalcriteria to accurately determine cCR, the duration of neoadjuvant treatment, therole of dose intensification (chemotherapy and/or radiotherapy), optimal followupprotocols, and the future perspectives of this approach. In the present review,we summarize the available evidence on the watch and wait strategy in thisclinical scenario, including ongoing clinical trials, QoL in these patients, and thecontroversies surrounding this treatment approach. | Fernando López-Campos Margarita Martín-Martín Roberto Fornell-Pérez Juan Carlos García-Pérez Javier Die-Trill Raquel Fuentes-Mateos Sergio López-Durán JoséDomínguez-Rullán Reyes Ferreiro AlejandroRiquelme-Oliveira Asunción Hervás-Morón Felipe Couñago | 2020 | World Journal of Gastroenterology2020，26，29： | 10 |
| 2 | 将安装于CON EDISON电网的带故障限流功能的高温超导电缆现状和进展显示文摘介绍了Hydra超导电缆项目的总体目标、设计准则、现状和进展,重点介绍了25 m原型电缆的结构设计、生产制造及型式试验。 | Maguire J Folts D Yuan J Henderson N Lindsay D Knoll D Rey C Duckworth R Gouge M Wolff Z Kurtz S | 2011 | 电网与清洁能源2011，27，5： | 3 |
| 3 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 4 | Toxicity of copper(II) ions to microorganisms in biological wastewater treatment systems显示文摘 | Valeria Ochoa-Herrera Glendy León Qais Banihani Jim A. Field Reyes Sierra-Alvarez | 2011 | Science of the Total Environment2011，，： | 2 |
| 5 | Replacements of juvenile manne shrimp,Penaeus monodon (Fabricius)for lysine and arginine显示文摘 | Millamena O M Baufista-Teruel M N Reyes O S | 1998 | Aquac1998，164，： | 1 |
| 6 | Speech/music classification based on distributed evolutionary fuzzy logic for intelligent audio coding显示文摘 | Munoz J E Reyes N R Galan S G | 2007 | Pattern Recognition and Image2007，4478，： | 1 |
| 7 | microRNA directed cleavage of ATHB15 mRNA regulates vascular development in Arabidopsis inflorescence stems 显示文摘 | Kim J Jung J H Reyes J L kim Y S Kim S Y Chung K S Kiln J A Lee M Lee Y Kim V N | 2005 | The Plant Journal2005，42，： | 1 |
| 8 | gammadelta T cells are required for maximal expression of allergic conjunctivitis显示文摘 | Reyes N J Mayhew E Chen PW | 2011 | Invest Ophthalmol Vis Sci2011，52，5： | 1 |
| 9 | Concerning the significance of paraoxonase-1 and SR-B1 genes in atherosclerosis显示文摘 | Rodríguez Esparragón F Hernández Trujillo Y Macías Reyes A | 2006 | Rev Esp Cardiol2006，59，2： | 1 |
| 10 | Dalteparin for the prevention of recurrence of placental-mediated complications of pregnancy in women without thrombophilia:a pilot randomized controlled trial显示文摘 | Rey E Garneau P David M Gauthier R Leduc L Michon N | 2009 | J Thromb Haemost2009，7，1： | 1 |
| 11 | The effect of airflowlimitation on the cause of death in patients with COPD显示文摘 | Alfageme I Reyes N Merino M | 2010 | Chron Respir Dis2010，7，3： | 1 |
| 12 | Estimating a socially optimal water price for irrigation versus an environmentally optimal water price through the use of Geographical Information Systems and Social Accounting Matrices显示文摘 | Esteban Castellano Pablo Martínez Anguita José I Elorrieta Marcelino Pellitero Concepción Rey | 2008 | Environmental and Resource Economics2008，，3： | 1 |
| 13 | Prediction and identificatima of Arabidopsis thah'ana microRNAs and their mRNA targets显示文摘 | WANG X J REYES J L CHUA N H | 2004 | Genome Biol2004，5，9： | 1 |
| 14 | ABA induction of miR159 controls transcript levels of two MYB factors during Arabidopsis seed germination 显示文摘 | Reyes J L Chua N H | 2007 | Plant Journal2007，49，4： | 1 |
| 15 | Parallel query processing on distributed clustering indexes 显示文摘 | Gil-Costa V Marin M Reyes N | 2009 | Journal of Discrete Algorithms2009，7，1： | 1 |
| 16 | Simultaneous determination of arsenic and selenium species in fish tissues using microwave-assisted enzymatic extraction and ion chromatography–inductively coupled plasma mass spectrometry显示文摘 | Laura Hinojosa Reyes Jorge L. Guzmán Mar G.M. Mizanur Rahman Bryan Seybert Timothy Fahrenholz H.M. Skip Kingston | 2009 | Talanta2009，，3： | 1 |
| 17 | Polarographic determination of nitrate in vegetables显示文摘 | Ximenes M I N Rath S Reyes F G R | 2000 | Talanta2000，51，1： | 1 |
| 18 | Scaling Analysis for the OSU AP600 Test Facility (APEX)显示文摘 | Jose N Reyes Jr Lawrence Hochreiter | 1998 | Nuclear Engineering and Design1998，186，： | 1 |
| 19 | Randomized,controlled trial comparing synchronized intermittent mandatory ventilation and synchronized intermittent mandatory ventilation plus pressure support in preterm infants显示文摘 | Reyes ZC Claure N Tauscher MK | 2006 | Pediatrics2006，118，4： | 1 |
| 20 | Photoelectrochemical degra- dation of lignin 显示文摘 | Pelegrini R Reyes J Duran N | 2000 | Journal of Applied Electrochemistry2000，30，8： | 1 |
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