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1内皮Notch信号的抑制阻碍脂肪酸转运并导致成年心脏的代谢和血管重塑显示文摘营养成分在被肌肉细胞代谢利用之前通过内皮细胞转运。然而,对于内皮运输过程的调节知之甚少。Notch信号传导是发育过程中代谢和血管生成的关键调控因子。在该研究中,Jabs等研究了成年小鼠内皮Notch信号的遗传和药理学调控如何影响内皮脂肪酸转运、心脏血管生成和心脏功能。刘青 叶鹏 Jabs M Rose AJ Lehmann LH Taylor J Moll I Sijmonsma TP Herberich SE Sauer SW Poschet G Federico G Mogler C Weis EM Augustin HG Yan M Gretz N Schmid RM Adams RH Gr9ne HJ Hell R Okun JG Backs J Nawroth PP Herzig S Fischer A 2018中华高血压杂志2018,26,3:6
2卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景 缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 2017国际脑血管病杂志2017,25,5:2
3Vascular complications of pancreatitis 显示文摘Mendelson RM Anderson J Marshall M 2005ANZJ Surg2005,75,12:1
4Immortalization of primary human keratinocytes by the helix-loop-helix protein Id-1显示文摘 Hasskarl J Grace M 1999Proc Natl Acad Sci USA1999,96,:1
5Extranodal marginalzone B-cell lymphoma of the salivary gland 显示文摘 Cruz RM Puligandla B 2001Ann Diagn Pathol2001,5,4:1
6Soluble triggering re- ceptor expressed on myeloid cells-1 : a biomarker for bacterial meningitis 显示文摘Determann RM Weisfelt M Gans J 2006Intensive Care Med2006,32,8:1
7Development of hypertension in rats during chronic exposure to cold显示文摘Fregly M J Kikta DC Threatte RM 1989J Appl physiol1989,66,2:1
8Nodular (keloidal)scleroderma显示文摘Perez-Wilson J Pujol RM Alejo M 1992Int J Dermatol1992,31,6:1
9Iris-fixated anterior chamber phakic in- traocular lens for myopia moves posteriorly with mydriasis显示文摘Cruysberg LP Doors M Berendschot TT De Brabander J We- bers CA Nuijts RM 2009J Refract Surg2009,25,4:1
10Backache in pregnancy 显示文摘Mantle M J Greenwood RM Currey HL 1977Rheumatol Rehabil1977,16,2:1
11The use of flow cytometry to detect expression of subunits encoded by 11 Salmonella enterica serotype Typhimurium fimbrial operons 显示文摘Humphries AD Raffatellu M Winter S Weening EA Droleskey R Zhang SP Figueiredo J Khare S Nunes J Adams LG Tsolis RM Baumler AJ 2003Mol Microbiol2003,48,5:1
12Evidence for a lan-guage quantitative trait locus on chromosome 7q in multiplexautism families显示文摘Alarcon M Cantor RM Liu J 2002Am J Hum Genet2002,70,:1
13The role of oxygen-free radicals in ischemic tissue injury in island skin flaps显示文摘Manson PN Anthenelli RM Im M J 1983Ann Surg1983,198,1:1
14Antitumor efficacy of Dexamethasone- loaded core- crosslinked polymeric micelles 显示文摘Coimbra M Rijken C J Stigte RM 2012Control Rel2012,163,:1
15Aspirin dose and six month outcome after an acute coronary syndrome 显示文摘Quinn M J Aronow HD Califf RM 2004J Am Coll Cardiol2004,43,6:1
16Prospective variation in the expression of the conjunctival mucin genes MUC5AC, MUC7, MUC16 and MUC17 before, during, and after contact lens wear显示文摘Corrales RM Galarreta D J Herreras JM Gonzalez M J Arranz I Saez V 2003Invest Ophthalmol Vis Sci2003,44,7:1
17Supramolecular Structure of fl-Cyclodextrin and Poly(ethylene oxide)- block-poly(propylene oxide)-block-poly(ethylene oxide) Inclusion Complexes显示文摘Tsai CC Leng SW Jeong KU Van Horn RM Wang CL Zhang WB Graham M J Huang J Ho RM Chen YM Lotz B Stephen Cheng ZD 2010Macromolecules2010,43,22:1
18Allergen immunotherapy forasthma显示文摘Abramson M J Puy RM Weiner JM 2003Coehrane Database Syst Rev2003,,01:1
19Soluble triggering receptor expressed on myeloid cells 1:a biomarker for bacterial meningitis显示文摘Determann RM Weisfelt M de Gans J 2006Intensive Care Med2006,32,8:1
20Laparoscopic and thoracoscopic esophagectomy显示文摘Levy RM Wizorek J Shende M 2010Adv Surg2010,44,:1
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