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	题名	作者	年代	出处	被引量
1	Cyclooxygenase-2 polymorphisms and the risk of esophageal adeno-or squamous cell carcinoma显示文摘AIM:To determine whether-1195 A→G and/or-765 G→C polymorphisms in Cyclooxygenase-2(COX-2 ) may have a risk modifying effect on the development of esophageal carcinoma in a Dutch Caucasian population.METHODS:Two study groups were recruited, 252 patients with esophageal carcinoma and 240 healthy controls, matched for race, age, gender and recruiting area.DNA was isolated from whole blood and used for genotyping.PCR products were digested with restriction enzymes and products were analyzed by agarose gel electrophoresis.Odds ratios(OR) and 95% confldence intervals(CI) were estimated.RESULTS:The distribution of the-1195 A→G polymorphism was signif icantly different in esophageal cancer patients compared to controls.The-1195 GG genotype resulted in a higher risk of developing esophageal adenocarcinoma(OR = 3.85, 95% CI:1.45-10.3) compared with the-1195 AA genotype as a reference.The-765 G→C genotype distribution was not different between the two groups.The GG/ GG haplotype was present more often in esophageal adenocarcinoma patients than in controls(OR = 3.45, 95% CI:1.24-9.58;with AG/AG as a reference).The same trends were observed in patients with squamous cell carcinomas, however, the results did not reach statistical signif icance.CONCLUSION:Presence of the COX-2-1195 GG genotype and of the GG/GG haplotype may result in a higher risk of developing esophageal carcinoma.	Jón O Kristinsson Paul van Westerveld Rene HM te Morsche Hennie MJ Roelofs T Wobbes Ben JM Witteman Adriaan CITL Tan Martijn GH van Oijen Jan BMJ Jansen Wilbert HM Peters	2009	World Journal of Gastroenterology2009，15，28：	11
2	INTERLEUKIN-10 AND THE INTERLEUKIN-10 RECEPTOR显示文摘	Kevin W. Moore Rene de Waal Malefyt Robert L. Coffman Anne O’Garra	2001	Annual Review of Immunology2001，，：	2
3	INTERLEUKIN-10 AND THE INTERLEUKIN-10 RECEPTOR显示文摘	Kevin W. Moore Rene de Waal Malefyt Robert L. Coffman Anne O’Garra	2001	Annual Review of Immunology2001，，：	1
4	Superior outcomes in children compared with adults after microsurgical resection of brain arteriovenous malformations显示文摘	Sanchez-Mejia Rene O Chennupati Sravana K Gupta	2006	Journal of Neurosurgery2006，105，2：	1
5	Identification of patients with high-risk lymph node-negative colorectal cancer and potential benefit from adjuvant chemotherapy显示文摘	Luis F Onate O Rene M	2004	Jpn J Clin Oncol2004，34，：	1
6	Identification of patients with high-risk lymph node-negative colorectal cancer and potential benefit from adjuvant chemotherapy显示文摘	LUIS F ONATE O RENE M	2004	Jpn J Clin Oncol2004，34，6：	1
7	Critical National Infrastructure Reliability Modeling and Analysis显示文摘	Stephen H Conrad Rene J LeClaire Gerard P O'Reilly	2006	Bell Labs Technical Journal2006，，：	1
8	The neuropsychological phenotype of velocardiofacial syndrome(VCFS):Relationship to psychopathology显示文摘	Renee L O Neill Isabelle B	2006	Archives of Clinical Neuropsychology2006，21，2：	1
9	Contracting processes and structures for systems of-systems acquisition显示文摘	Rene G R Thomas V H John S O	2012	Systems Engi- neering2012，15，4：	1
10	Identification of patients with high-risk lymph node-negative colorectal cancer and potential benefit from adjuvant chemotherapy 显示文摘	Luis F Onate O Rene M	2004	Jpn J Clin Oncol2004，34，6：	1
11	Usefulness of Aminoterminal Pro-Brain Natriuretic Peptide Testing for the Diagnostic and Prognostic Evaluation of Dyspneic Patients With Diabetes Mellitus Seen in the Emergency Department (from the PRIDE Study)显示文摘	Michelle O’Donoghue Patrick Kenney Eveline Oestreicher Saif Anwaruddin Aaron L. Baggish Daniel G. Krauser Annabel Chen Roderick Tung Renee Cameron James L. Januzzi	2007	The American Journal of Cardiology2007，，9：	1
12	The Application of Reconfigurable Logic to High Speed CNC Milling Machines Controllers显示文摘	Roque A O Rene de J R Gilberto H	2008	Control Engineering Practices2008，16，6：	1
13	Skeletonizing en bloc esophagectomy for cancer显示文摘	Jean-Bernard O Rene F	1997	Ann Surg1997，234，1：	1
14	Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo 显示文摘	Jesse J Smith Renee Deehan Kenney David J Gagne Brian P Frushour William Ladd Heidi L Galonek Kristine Israelian Jeffrey Song Giedre Razvadauskaite Amy V Lynch David P Carney Robin J Johnson Siva Lavu Andre Iffland Peter J Elliott Philip D Lambert Keith O Elliston Michael R Jirousek Jill C Milne and Olivier Boss	2009	BMC Systems Biology2009，284，27：	1
15	Pathways connecting neighborhood influences and mental well-being: Socioeconomic position and gender differences显示文摘	Jessica Burke Patricia O’Campo Christina Salmon Renee Walker	2009	Social Science & Medicine2009，，7：	1
16	A phylogenetic comparison of red deer and wapiti using mitochondrial DNA显示文摘	Renee O Polziehn Curtis Strobeck		0，，03：	1
17	Determination of methanesulfonic acid and non-sea-salt sulfate in single marine aerosol particles显示文摘	Kolaitis Leonidas N Bruynseels Frank J Van Grieken Rene E Andreae Meinrat O	1989	Environmental Science and Technology1989，23，2：	1
18	Meningioma:analysis of recurrence and progression follwing neurosurgical resection显示文摘		1985	J Neurosurg1985，62，：	1
19	Identification of patients with high-risk lymph node-negative coloreetal cancer and potential benefit from adjuvant chemotherapy显示文摘	LuisF onate O 'Rene M	2004	Jpn J Clin Oncol2004，34，6：	1
20	Uptake of lead,cadmium and zinc by a novel bacterial exopolysaccharide显示文摘	MARTINE L RENE O JEAN G	1997	Water Research1997，31，5：	1

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