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	题名	作者	年代	出处	被引量
1	减少卵子老化对于补救性卵母细胞单精子显微注射结局的影响显示文摘Objective: To evaluate the results of a novel protocol that allows to rescue IVF unfertilized oocytes by intracytoplasmic sperm injection (ICSI).Design: Prospective clinical trial.Setting: Private reproductive medical center.Patient(s): Thirty patients undergoing IVF.Intervention(s): Controlled ovarian stimulation (COS), conventional IVF, rescue ICSI, embryo culture, and embryo transfer.Main Outcome Measure(s): Identification of unfertilized IVF oocytes 6 hours after insemination and fertilization, and developmental rates of those oocytes after rescue microinjection, as well implantation and pregnancy rates (PR).Result(s): All oocytes (392) from 30 patients were inseminated with standard IVF 3 hours after ovum pick- up.Polar body (PB) status was checked at decumulation and rechecked 3 hours later.Eighty- two oocytes were fertilized after IVF alone and 184 nonactivated oocytes (failed fertilization) were rescue microinjected and 166 of them fertilized (20 patients).Cleavage stage on day 2 was significantly more advanced and embryo grade was higher after standard IVF fertilization than after rescue ICSI.Eight of the 30 embryos transferred were implanted in the IVF- only patients (27% )- and 8 of 68 embryos in the rescue ICSI patients (12% ).Conclusion(s): Rescue ICSI of unfertilized IVF oocytes 6 hours after insemination (9 hours after egg retrieval) can provide normal fertilization, embryo development, and pregnancy; however, corresponding outcome parameters tend to be impaired in comparison to the standard IVF fertilization results.	Nagy Z.P. Rienzi L.F. Ubaldi F.M. 朱亮	2006	世界核心医学期刊文摘(妇产科学分册)2006，2，9：	2
2	Cumulative pregnancy rates after transfer of fresh and thawed embryos显示文摘	Ubaldi CF Rienzi L Baroni E	2004	Eur J Obstetrics Gynecol Reprod Biol2004，115，7：	1
3	Predictive value of oocyte morphology in human IVF : a systematic review of the lite- ratureHum显示文摘	Rienzi L Vajta G Ubaldi F	2011	Reprod Update2011，17，1：	1
4	Effect of reduced oocyte aging on the outcome of recue intracytoplasmic sperm injection显示文摘	Nagy ZP Rienzi LF Ubaldi FM	2006	Fertil Steril2006，85，4：	1
5	Morphological selection of gametes显示文摘	UBALDI F RIENZI L	2008	Placenta2008，29，：	1
6	Predictive value of oocyte morphology in human IVP: a systematic review of the literature显示文摘	Rienzi L Vajta G Ubaldi F	2011	Hum Reprod Update2011，17，1：	1
7	Developmental potential of fully intact and partially damaged cryopreserved embryos after laser-assisted removal of necrotic blastomeres and post-thaw cuhure selection显示文摘	RIENZI L UBALDI F IACOBELLI M	2005	Fertil Steril2005，84，4：	1
8	Zona-free embryo cul-ture:Is it a viable option to improve pregnancy rates?显示文摘	VAJTA G RIENZI L BAVISTER B D	2010	Re-prod Biomed Online2010，21，1：	1
9	Reduction of the incidence of sperm DNA fragmentation by oral antioxidant treatment 显示文摘	Greco E Iaeobelli M Rienzi L	2005	J Andro12005，26，3：	1
10	Effect of reduced oocyte aging on the outcome of rescue intracytoplasmic sperm injection 显示文摘	Nagy Z Rienzi L Ubaldi F	2006	Fertil Steri12006，85，：	1
11	Caspase-dependent and -independent DNA fragmentation in Sertoli and germ cells from men with primary testicular failure:relationship with histological diagnosis显示文摘	Tesarik J Ubaldi F Rienzi L	2004	Hum Reprod2004，19，2：	1
12	Preincubation of human oocytes may improve fertilization and embryo quality after intracytoplasmic sperm injection显示文摘	Rienzi L Ubaldi F Anniballo R	1998	Hum Reprod1998，13，4：	1
13	Predictive value of oocyte morphology in human IVF显示文摘	Rienzi L Vajta G Ubaldi F		A systematic review of the literature0，，：	1
14	Differentiation of spermatogenic cells during in-vitro culture of testicular biopsy samples from patients with obstructive azoospermia:effect of recombinant follicle stimulating hormone显示文摘	Tesarik J Greco E Rienzi L	1998	Hum Reprod1998，13，：	1
15	Vascular smooth muscle cell growth and insulin regulation of mitogen-activated protein kinase in hypertension显示文摘	Begum N Song Y Rienzie J	1998	Am J Physiol1998，275，：	1
16	Laser assisted removal of necrotic blastomeres from cryopreserved embryos that were partially damaged 显示文摘	Rienzi L Nagy ZP Ubaldi F	2002	Fertil Steril2002，77，6：	1
17	Differentiation of spermato genic cells during in-vitro culture of testicular biopsy samples from patients with obstructive azoospermia:effect of recombinant follicle stimulating hormone显示文摘	TESARIK J GRECO E RIENZI L	1998	Hum Reprod1998，13，10：	1
18	In-vitro effects of FSH and testosterone withdrawal on caspase activation and DNA fragmentation in different cell types of human seminiferous ep?ithelium显示文摘	TESARIKJ MARTINEZ F RIENZI L	2002	Hum Reprod2002，17，7：	1
19	management oof poor responders in IVF显示文摘	UBALDI F M RIENZI L FERRERO S	2005	Reprod Diomed Online2005，10，2：	1
20	Effect of reduced oocyte aging on the outcome of rescue intracytoplasmic sperm injection 显示文摘	Nagy ZP Rienzi LF Ubaldi FM	2006	Ferti Steril2006，85，4：	1

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