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| 1 | Randomized trial in malignant biliary obstruction:Plastic vs partially covered metal stents显示文摘AIM:To compare efficacy and complications of par-tially covered self-expandable metal stent(pcSEMS)to plastic stent(PS)in patients treated for malignant,infrahilar biliary obstruction.METHODS:Multicenter prospective randomized clinical trial with treatment allocation to a pcWallstent(SEMS)or a 10 French PS.Palliative patients aged≥18,for infrahilar malignant biliary obstruction and a Karnofsky performance scale index>60%from 6 participating North American university centers.Primary endpoint was time to stent failure,with secondary outcomes of death,adverse events,Karnofsky performance score and short-form-36 scale administered on a three-monthly basis for up to 2 years.Survival analyses were performed for stent failure and death,with Cox proportional hazards regression models to determine significant predictive characteristics.RESULTS:Eighty-five patients were accrued over 37mo,42 were randomized to the SEMS group and 83patients were available for analyses.Time to stent failure was 385.3±52.5 d in the SEMS and 153.3±19.8 d in the PS group,P=0.006.Time to death did not differ between groups(192.3±23.4 d for SEMS vs211.5±28.0 d for PS,P=0.70).The only significant predictor was treatment allocation,relating to the time to stent failure(P=0.01).Amongst other measured outcomes,only cholangitis differed,being more common in the PS group(4.9%vs 24.5%,P=0.029).The small number of patients in follow-up limits longitudinal assessments of performance and quality of life.From an initially planned 120 patients,only 85 patients were recruited.CONCLUSION:Partially covered SEMS result in a longer duration till stent failure without increased complication rates,yet without accompanying measurable benefits in survival,performance,or quality of life. | Peter L Moses Khalid M AlNaamani Alan N Barkun Stuart R Gordon Roger D Mitty M Stanley Branch Thomas E Kowalski Myriam Martel Viviane Adam | 2013 | World Journal of Gastroenterology2013，19，46： | 6 |
| 2 | Dyslipidemia management in primary prevention of cardiovascular disease:Current guidelines and strategies显示文摘Cardiovascular disease is the leading cause of death in the United States. In 2010, the Centers for Disease Control and Prevention estimated that $444 billion was spent on cardiovascular diseases alone, about $1 of every $6 spent on health care. As life expectancy continues to increase, this annual cost will also increase, making costeffective primary prevention of cardiovascular disease highly desirable. Because of its role in development of atherosclerosis and clinical events, dyslipidemia management is a high priority in cardiovascular prevention. Multiple major dyslipidemia guidelines have been published around the world recently, four of them by independent organizations in the United States alone. They share the goal of providing clinical guidance on optimal dyslipidemia management, but guidelines differ in their emphasis on pharmacotherapy, stratification of groups, emphasis on lifestyle modification, and use of a fixed target or percentage reduction in low density lipoprotein cholesterol. This review summarizes eight major guidelines for dyslipidemia management and considers the basis for their recommendations. Our primary aim is to enhance understanding of dyslipidemia management guidelines in patient care for primary prevention of future cardiovascular risk. | Aditya D Hendrani Tolulope Adesiyun Renato Quispe Steven R Jones Neil J Stone Roger S Blumenthal Seth S Martin | 2016 | World Journal of Cardiology2016，8，2： | 5 |
| 3 | Stability and structure of activated macrocyclic ligands with biological applications显示文摘 | Motekaitis R J Rogers B E Reichert D E | 1996 | Inorg Chem1996，35，： | 2 |
| 4 | Peripheral clearance of amyloid beta peptide by complement C3 -dependent adherence to erythrocytes 显示文摘 | ROGERS J LI R MASTROENI D | 2006 | Neurobiol Aging2006，27，12： | 1 |
| 5 | In vitro replication of mouse hepatitis virus strain A59显示文摘 | Compton J R Rogers D B Holmes K V | 1987 | J Virol1987，61，： | 1 |
| 6 | Quality management influences on logistics performance显示文摘 | Ronald D Anferson Roger E Jerman Michael R Crum | 1998 | Transpm Res-E (Logistics and Transpm Rev)1998，34，2： | 1 |
| 7 | Deciphering the biology of My cobacterium tuberculosis from the complete genome sequence 显示文摘 | Cole S T Brosch R Parkhill J Gamier T Churcher C Harris D Gordon S V Eiglmeier K Gas S Barry C E Tekaia F Badcock K Basham D Brown D Chillingworth T Cormor R Davies R Devlin K FeltweU T Gentles S Hamlin N Holroyd S Hornsby T Jagels K Kroghs A McLean J Moule S Murphy L Oliver K Osborne J Quail M A Rafandream M A Rogers J Rutter S Seeger K Skelton J Squaraes R Squares S Sulston J E Taylo K Whitehead S Barrell B G | 1998 | Nature1998，393，： | 1 |
| 8 | Ionic liquids are not always green: hydrolysis of 1-butyl-3- methylimidazolium hexafluorophosphate 显示文摘 | SWATLOSKI R P HOLBREY J D ROGERS R D | 2003 | Green Chem02003，5，： | 1 |
| 9 | Liquid clathrate formation in ionic liquid-aromatic mixtures显示文摘 | HOLBREY J D REICHERT W M NIEUWENHUYZEN M SHEPPARD O HARDACRE C ROGERS R D | 2003 | Chem Commun2003，，47： | 1 |
| 10 | Enantioselective highperformanceliquid chromatographic determination ofomeprazole in human plasma显示文摘 | CAIRNA A M CHIOU R H ROGERS J D | 1995 | J Chromatogr B1995，66，： | 1 |
| 11 | Ionic liquid processing of cellulose显示文摘 | Wang H Gurau G Rogers R D | | 0，，04： | 1 |
| 12 | Impact factors of mercury volatile from soils 显示文摘 | Rogers R D Mcfarlane J C | 1979 | Journal of Environmental Quality1979，，8： | 1 |
| 13 | Isolation and Characterization of Novel Psychrophilic, Neutrophilie, Fe-Oxidizing, Chemolithoautotrophic α-and β-Proteobacteria from the Deep Sea 显示文摘 | Edwards K J Rogers D R Wirsen C O | 2003 | Applied and Environmental Microbiology2003，69，5： | 1 |
| 14 | 50 years old and still going strong 显示文摘 | Thomas M Hooton R D Rogers C | 2012 | Concrete International2012，34，11： | 1 |
| 15 | Epidnral analgesia and active management of labor:effects on length of labor and mode of delivery显示文摘 | Rogers R Gilson G Kammerer Douk D | 1999 | Obstet Gynecol1999，93，6： | 1 |
| 16 | Ionic liquids-Solvents of the future显示文摘 | Rogers R D Seddon K R | 2003 | Science2003，，302： | 1 |
| 17 | Haemagglutinins of the phaeophyceae and non-specific aggregation phenomena by polyphenols 显示文摘 | Rogers D J Loveless R W | 1985 | Bot Mar1985，28，4： | 1 |
| 18 | The chemistry of imidates显示文摘 | Roger R Neilson D G | 1961 | Chem Review1961，61，： | 1 |
| 19 | Differences between forward and reverse logistics in a retail environment 显示文摘 | Tihben Lembke R Rogers D | 2002 | Supply Chain Management: An Internatioanl Journal2002，7，5： | 1 |
| 20 | The aRb rela- tion in the calculation of rain attenuation显示文摘 | OLSEN R ROGERS D V HODGE D | 1978 | IEEE Transactions on Antennas and Propagation1978，26，2： | 1 |
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