|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Definition of colorectal anastomotic leakage: A consensus survey among Dutch and Chinese colorectal surgeons显示文摘AIM To determine the level of consensus on the definition of colorectal anastomotic leakage(CAL) among Dutch and Chinese colorectal surgeons.METHODS Dutch and Chinese colorectal surgeons were asked to partake in an online questionnaire. Consensus in the online questionnaire was defined as > 80% agreement between respondents on various statements regarding a general definition of CAL,and regarding clinical and radiological diagnosis of the complication.RESULTS Fifty-nine Dutch and 202 Chinese dedicated colorectal surgeons participated in the online survey. Consensus was found on only one of the proposed elements of a general definition of CAL in both countries: ‘extravasation of contrast medium after rectal enema on a CT scan'. Another two were found relevant according to Dutch surgeons: ‘necrosis of the anastomosis found during reoperation',and ‘a radiological collection treated with percutaneous drainage'. No consensus was found for all other proposed elements that may be included in a general definition.CONCLUSION There is no universally accepted definition of CAL in the Netherlands and China. Diagnosis of CAL based on clinical manifestations remains a point of discussion in both countries. Dutch surgeons are more likely to report ‘subclinical' leaks as CAL,which partly explains the higher reported Dutch CAL rates. | Stefanus J van Rooijen Audrey CHM Jongen Zhou-qiao Wu Jia-fu Ji Gerrit D Slooter Rudi MH Roumen Nicole D Bouvy | 2017 | World Journal of Gastroenterology2017，23，33： | 4 |
| 2 | 布鲁氏菌引起的巨噬细胞依赖性树突状细胞迁移与免疫应答显示文摘目的:研究阴道巨噬细胞清除后小鼠对布鲁氏菌疫苗的免疫应答机制。方法:BALB/c小鼠60只随机分为3组,每组20只,实验组小鼠阴道内滴注脂质体包裹的clodronate以清除阴道巨噬细胞,3d后阴道滴注10μL布鲁氏菌疫苗(含6×108个布鲁氏菌)。同时设空脂质体对照组(不含clo-dronate)和PBS对照组。依次在12、24、36、72h收集小鼠阴道、髂内淋巴结和血液。采用免疫组织化学染色法观察阴道巨噬细胞清除效果和树突状细胞(DC)的迁移,并用ELISA法检测血清中IFN-γ和IL-4的含量。收集小鼠腹腔液制备巨噬细胞进行细胞培养,1.2×106个巨噬细胞中加入布鲁氏菌疫苗10μL,于不同时间点对巨噬细胞进行姬姆萨染色,观察巨噬细胞的变化。结果:清除巨噬细胞组小鼠接种布鲁氏菌疫苗后,髂内淋巴结中S-100阳性DC数量没有明显的变化,IFN-γ和IL-4的含量也没有明显的升高。非清除组中,不同的时间点,髂内淋巴结中S-100阳性DC明显增多,与PBS对照组相比,IFN-γ含量显著增高,而IL-4则没有明显变化。体外巨噬细胞负载布鲁氏菌疫苗发现,随着时间的延长,巨噬细胞吞噬布鲁氏菌逐渐增多,在12h,巨噬细胞开始出现坏死性凋亡。结论:小鼠在对布鲁氏菌疫苗的免疫应答中,DC的迁移是巨噬细胞依赖性的,并且这种依赖性有可能是由布鲁氏菌抗原成分在细胞间间接传递引起的。 | 韩丽滨 董炳梅 李妍 何媛娜 Nico van Rooijen 王少华 付景丽 王家鑫 | 2009 | 细胞与分子免疫学杂志2009，25，6： | 3 |
| 3 | 迁移性树突状细胞与淋巴结内树突状细胞在抗B.suis免疫应答中的作用显示文摘目的:研究迁移性树突状细胞与淋巴结内树突状细胞在抗猪布鲁氏菌免疫应答中的作用。方法:48只BALB/c小鼠随机分为3组:Ⅰ组为正常对照组,阴道滴注PBS;Ⅱ组为巨噬细胞(Mφ)清除组,每只小鼠阴道滴入清除剂;Ⅲ组为未清除Mφ组,每只小鼠阴道滴注同体积的liposome-PBS;48小时后Ⅱ组、Ⅲ组均阴道接种猪布鲁氏菌,对照组阴道滴注PBS。各组小鼠分别在接种12、24、48和72小时采集血液和髂内淋巴结,采用免疫组织化学染色法观察淋巴结内树突状细胞(DC)的分布,用ELISA法检测血清中IFN-γ和IL-4的含量。结果:未清除Mφ组小鼠接种布鲁氏菌后髂内淋巴结内有大量DC迁移,至12小时血清IFN-γ水平显著增高,与对照组相比差异显著(P<0.05),48小时达到高峰,显著高于对照组(P<0.01)。清除Mφ组小鼠接种布鲁氏菌后,髂内淋巴结内没有明显的DC迁移,各时间点血清IFN-γ水平明显高于PBS对照组(P<0.05),但明显低于未清除Mφ组(P<0.05)。各组IL-4水平的差异无统计学意义(P>0.05)。结论:迁移性DC和淋巴结内DC在启动抗布鲁氏菌细胞免疫应答中均发挥重要作用,并具有协同作用的特点。 | 曹志然 董炳梅 程君生 王蓓 何媛娜 付景丽 Nico Van Rooijen 丁家波 毛开荣 王家鑫 | 2010 | 中国免疫学杂志2010，26，8： | 3 |
| 4 | Extramedullary Hematopoiesis Generates Ly-6Chigh Monocytes That Infiltrate Atherosclerotic Lesions显示文摘 | Clinton S. Robbins Aleksey Chudnovskiy Philipp J. Rauch Jose-Luiz Figueiredo Yoshiko Iwamoto Rostic Gorbatov Martin Etzrodt Georg F. Weber Takuya Ueno Nico van Rooijen Mary Jo Mulligan-Kehoe Peter Libby Matthias Nahrendorf Mikael J. Pittet Ralph Weisslede | 2012 | Circulation2012，，2： | 2 |
| 5 | CD47 Is Upregulated on Circulating Hematopoietic Stem Cells and Leukemia Cells to Avoid Phagocytosis显示文摘 | Siddhartha Jaiswal Catriona H.M. Jamieson Wendy W. Pang Christopher Y. Park Mark P. Chao Ravindra Majeti David Traver Nico van Rooijen Irving L. Weissman | 2009 | Cell2009，，2： | 2 |
| 6 | CD47 Is an Adverse Prognostic Factor and Therapeutic Antibody Target on Human Acute Myeloid Leukemia Stem Cells显示文摘 | Ravindra Majeti Mark P. Chao Ash A. Alizadeh Wendy W. Pang Siddhartha Jaiswal Kenneth D. Gibbs Nico van Rooijen Irving L. Weissman | 2009 | Cell2009，，2： | 2 |
| 7 | Toll‐like receptor 2 and palmitic acid cooperatively contribute to the development of nonalcoholic steatohepatitis through inflammasome activation in mice显示文摘 | Kouichi Miura Ling Yang Nico van Rooijen David A. Brenner Hirohide Ohnishi Ekihiro Seki | 2013 | Hepatology2013，，2： | 2 |
| 8 | Toll-like receptor-4 signaling and Kupffer cells play pivotal roles in the pathogenesis of non-alcoholic steatohepatitis显示文摘 | Chantal A. Rivera Patrick Adegboyega Nico van Rooijen Arlene Tagalicud Monique Allman Matthew Wallace | 2007 | Journal of Hepatology2007，，4： | 2 |
| 9 | Plant seed oil-bodies as carriers for foreign proteins显示文摘 | VAN ROOIJEN G J MOLONEY M M | 1995 | Biotechnology (NY)1995，13，： | 1 |
| 10 | The liposome mediated macrophage 'suicide' technique 显示文摘 | Van Rooijen N | 1989 | J Immunol Meth1989，124，： | 1 |
| 11 | Liposome mediated depletion of macrophage:mechanism of action,preparation of liposomes and applications显示文摘 | VAN ROOIJEN N SANDERS A | 1994 | J ImmunolMeth1994，174，： | 1 |
| 12 | The liposome mediated macrophages'suicide' technique 显示文摘 | Nico van Rooijen N | 1989 | Immunol Methd1989，124，： | 1 |
| 13 | The role of macrophages in Acanthamoeba keratitis显示文摘 | van Klink F Taylor WM Alizadeh H Jager MJ van Rooijen N Niederkorn JY | 1996 | Invest Ophthalmol Vis Sci1996，37，： | 1 |
| 14 | Molecular cloning,transcriptional analysis and nucleotide sequence of lacR,a gene encoding the repressor of the lactose phosphotransferase system of Lactococcus lactis显示文摘 | VAN ROOIJEN R J DE VOS W M | 1990 | J Biol Chem1990，265，18： | 1 |
| 15 | Acute CD4+ T lymphocyte-dependent interleukin-1-driven arthritis selectively requires interleukin-2 and interleukin-4,joint macrophages,granulocyte-macrophage colony-stimulating factor,interleukin-6,and leukemia inhibitory factor显示文摘 | Lawlor KE Wong PK Campbell IK van Rooijen N Wicks IP | 2005 | Arthritis Rheum2005，52，12： | 1 |
| 16 | Thin-layer response and spectral bandwidth显示文摘 | De Voogd N den Rooijen N | 1983 | Geophysics1983，48，1： | 1 |
| 17 | Autogenous radial-cephai-ic or prosthetic brachial-anticubital forearm loop avfin patients with compromised vessel 显示文摘 | Rooijens P P Burgmans J P Yo T I | 2005 | J Vasc Surg2005，42，3： | 1 |
| 18 | Heme oxygen- ase-2 deletion impairs macrophage fimction: implication in wound healing 显示文摘 | Bellner L Marrazzo G van Rooijen N | 2015 | FASEB J2015，29，1： | 1 |
| 19 | Liposome mediated depletion of macrophages :mechanism of action ,preparation of liposomes and applications显示文摘 | Nico Van Rooijen Sanders A | 1994 | Immunol Methd1994，174，： | 1 |
| 20 | Role of macrophages in virus-induced airway hyperresponsiveness and neuronal M2 muscarinie receptor dysfunction显示文摘 | Lee A M Fryer A D van Rooijen N | 2004 | Am J Physiol Lung Cell Mol Physiol2004，286，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员