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| 1 | Prospective evaluation of the short access cholangioscopy for stone clearance and evaluation of indeterminate strictures显示文摘BACKGROUND: Peroral cholangioscopy facilitates diagnosis and therapy of biliary disorders. This study prospectively evaluated a new short access cholangioscopy. METHODS: Consecutive patients were included as follows: difficult stones(group 1) underwent cholangioscopy with electrohydraulic lithotripsy and indeterminate biliary strictures(group 2) were evaluated with macroscopic assessment and cholangioscopy guided biopsy sampling. We evaluated the complete stone clearance rate(group 1) and diagnostic accuracy(group 2). Follow-up was performed over a median of 13 and 16 months, respectively.RESULTS: Group 1(n=21): complete stone clearance defined as lack of stones in cholangiography and stone removal during cholangioscopy was achieved in 15(71.4%) patients. Clinical stone clearance defined as lack of symptoms, laboratory abnormalities and hospital visits during follow-up, irrespective of stone clearance was evident in 17(81.0%) patients. One serious adverse event occurred(bile duct perforation). Group 2(n=28): malignancy was confirmed in 15 patients. Sensitivity, specificity and diagnostic accuracy of cholangioscopy were 85.7%, 75.0% and 80.7%, respectively. Sensitivity, specificity and diagnostic accuracy of biopsies were 54.5%, 100.0% and 72.2%, respectively. No serious adverse events occurred, and one patient was lost to follow-up.CONCLUSIONS: The novel system enabled complex stone treatment and biliary stricture diagnosis. Cholangioscopy outperformed direct biopsy regarding characterization of indeterminate strictures. | Athanasios D Sioulas Muhammad A El-Masry Stefan Groth Guido Schachschal Mario Anders Thomas Rosch Ulrike Denzer | 2017 | Hepatobiliary & Pancreatic Diseases International2017，16，1： | 2 |
| 2 | Quantum chemical modeling of electron hole transfer through stacks of normal and modified pairs of nucleobases显示文摘 | Voityuk A A Rosch N | 2002 | J Phys Chem B2002，，106： | 1 |
| 3 | A Prospective Comparison of the Diagnostic Accuracy of ERCP, MRCP, CT and EUS in Biliary Strictures显示文摘 | Rosch T Meining A Fruhmorgen S | 2002 | Gastrointest Endosc2002，55，7： | 1 |
| 4 | Safety and tolerability of adjuvant topical tacrolimus treatment in boys with lichen sclerosus:a prospective phase Ⅱ study显示文摘 | Ebert A K Rosch W H Vogt T | 2008 | Eur Urol2008，54，4： | 1 |
| 5 | Enzymatic reduction of the ct, 13-unsaturated carbon bond in citral显示文摘 | Muller A Haner B Rosche B | 2006 | Journal of Molecular Catalysis B: Enzymatic2006，38，36： | 1 |
| 6 | Clinical skills of veteri-nary students-a cross-sectional study of the self-concept andexposure to skills training in Hannover, Germany 显示文摘 | Rosch T Schaper El Tipold A | 2014 | BMCVeterinary Research2014，，10： | 1 |
| 7 | A prospective comparison of the diagnostic accuracy of ERCP,MRCP,CT,and EUS in biliary strictures 显示文摘 | Rosch T Meining A Fruhmorgen S | 2002 | Gastrointest Endosc2002，55，7： | 1 |
| 8 | Prevention of soc cer injuries: A prospective intervention study in youth amateur players显示文摘 | JUNGE A ROSCH D PETERSON L | 2002 | Am J Sports Med2002，30，5： | 1 |
| 9 | Pregnancy course and outcome after intracytoplasmic sperm injection: a controlled,prospective cohort study显示文摘 | Katalinic A Rosch C Ludwig M | 2004 | Fertil Steril2004，81，6： | 1 |
| 10 | Biodiversity of denitrifying anddinitrogen-fixing bacteria in an acid forest soil 显示文摘 | Rosch C Mergel A Bothe H | 2002 | Applied and Environmental Microbiology2002，68，8： | 1 |
| 11 | Asymmetric alkene re- duction by yeast old yellow enzymes and by a novel Zy- momonas mobilis reduetase显示文摘 | MULLER A HAUER B ROSCHE B | 2007 | Biotechnology and bioengineer- ing2007，98，1： | 1 |
| 12 | A prospective comparison of the diagnostic accuracy of ERCP, MRCP, CT and EUS in biliary strictures 显示文摘 | Rosch T Melning A Fruhmorgen S | 2002 | Gastrointest Endosc2002，55，： | 1 |
| 13 | Biodiversity of denitrifying and dinitrogen_fixing bacteria in an acid forest soil 显示文摘 | Rosch C Mergel A Bothe H | 2002 | Appl Environ Mierobiol2002，68，： | 1 |
| 14 | Psychological and Sport-Specific Characteristics of Football Players 显示文摘 | Junge A Dvorak J Rosch D | 2000 | The American Journal of Sports Med- icine2000，28，5： | 1 |
| 15 | Asymmetric alkene reduction by yeast Old Yellow Enzymes and by a novel Zymomonas mobilis reductase 显示文摘 | Müller A Hauer Ba Rosche B | 2007 | Biotechnol Bioeng2007，98，： | 1 |
| 16 | A prospective comparison of the diagnostic accuracy of ERCP , MRCP, CT, and EUS in biliary strictures 显示文摘 | Rosch T Meining A Fruhmorgen S | 2002 | Gastrointest Endosc2002，55，7： | 1 |
| 17 | Structural investigations of flavonol glycosides from sea buckthorn (Hippophae rhamnoides) pomace by NMR spectroscopy and HPLC-ESI-MSn显示文摘 | Rosch D Krumbein A Mügge C | 2004 | J Agric Food Chem2004，52，13： | 1 |
| 18 | Enzymatic reduction of the α,β-unsaturated carbon bond in citral 显示文摘 | Müller A Hauer B Rosche B | 2006 | J Mol Catal B:Enzym2006，38，： | 1 |
| 19 | A prospective compari son of the diagnostic accuracy of ERCP, MRCP, CT and EUS in bil iary strictures显示文摘 | Rosch T Meining A Fruhmorgen S | 2002 | Gastrointest Endosc2002，55，7： | 1 |
| 20 | Stereospecific alkyne reduction:novel activity of old yellow enzymes 显示文摘 | Müller A Stürmer R Hauer B Rosche B | 2007 | Angew Chem Int Ed2007，46，： | 1 |
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