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| 1 | Preferential CTL targeting of Gag is associated with relative viral control in long-term surviving HIV-1 infected former plasma donors from China显示文摘它通常被相信细胞毒素的 T 淋巴细胞(CTL ) 玩的那 CD8 + 在限制人的免疫不全病毒类型 1 的复制(HIV-1 ) 并且在决定感染的结果,和这效果可以部分优先地取决于产品是哪个 HIV 的一个关键角色指向了。在以前的血浆施主(FPD ) 的一个队探讨在 HIV-1-specific CTL 回答和病毒复制之间的关联,天真的 FPD 与 HIV-1 clade B' 紧张感染了的 143 antiretroviral 治疗与 IFN-γ 为 HIV-1-specific CTL 回答被估计;在由使用盖住整个一致 clade B proteome 的重叠的肽(OLP ) 的单个肽水平的 Elispot 试金。由使用一个枪兵的等级关联分析,当是断然相关到 CD4 计数时,我们发现在全部的病毒特定的 CTL 活动之中的作呕特定的 CTL 回答的比例相反地与病毒的负担被相关,与与增加的病毒的负担被联系并且减少的Pol特定、Env特定的回答对比, CD4 数。另外, Vpr-specifc CTL 回答显示出类似的保护的效果与作呕回答,但是与识别的低得多的频率。显著地,我们也观察了在 HLA 之间的一个协会 --*30/B*13/Cw*06 haplotype 和可能由于的更低的病毒的负担限制了作呕特定的 CTL 回答。因此,我们的数据在疾病控制表明作呕特定的 CTL 回答的突出的角色。HLA 的优点 -- 在病毒的控制的 *30/B*13/Cw*06 haplotype 可以在学习个人与作呕特定的 CTL 回答的贡献被联系。 | Mingming Jia Kunxue Hong Jianping Chen Yuhua Ruan Zhe Wang Bing Su Guoliang Ren Xiaoqing Zhang Zhen Liu Quanbi Zhao Dan Li Hong Peng Marcus Altfeld Bruce D Walker Xu G Yu Yiming Shao | 2012 | Cell Research2012，22，5： | 3 |
| 2 | Quantitative X-ray powder diffraction analysis of clay minerals in Australian coals using Rietveld methods显示文摘 | RUAN C D WARD C R | 2002 | Appl Clay Sci2002，21，56： | 2 |
| 3 | Thermal decomposition of bauxite minerals: infrared emission spectroscopy of gibbsite显示文摘 | Kloprogge J T Ruan H D Frost R L | 2004 | Boehmite and Diaspore2004，37，6： | 1 |
| 4 | The behavior of hydroxyl units of synthetic goethite and its dehydroxylated product hematite显示文摘 | Ruan H D Frost R L Kloprogge J T | 2001 | Spectrochim Acta Part A2001，57，： | 1 |
| 5 | Willingness to be circumcised for preventing HIV among Chinese men who have sex with men 显示文摘 | Ruan Y Qian H Z Li D | 2009 | AIDS Patient Care STDS2009，23，5： | 1 |
| 6 | Actin, a reliable marker of internal control 显示文摘 | RUAN W J LAI M D | 2007 | Climica Chimica Acta2007，385，12： | 1 |
| 7 | Solid - Phase Grafting of Glycidyl Methacrylate onto Polypropylane显示文摘 | Y K PAN J M RUAN D F ZHAN | 1996 | J Appl Polym Sci1996，65，： | 1 |
| 8 | Lack of effects of vitamin E on aluminum-induced deficit of synaptic plasticity in rat dentate gyrus in vivo显示文摘 | Wang M Ruan D Y Chen J T | 2002 | Food Chem Toxicol2002，40，： | 1 |
| 9 | Low major histocompatibility complex class Ⅱ DQA diversity in the giant panda (Ailuropoda melanoleuca) 显示文摘 | Zhu L Ruan X D Ge Y F | 2007 | BMC Genet2007，8，： | 1 |
| 10 | Customized Products:A Competitive Analysis显示文摘 | Syam N B Ruan R Hess J D | 2005 | Marketing Science2005，24，4： | 1 |
| 11 | ct-Resolution principle based on lattice-valued first-order logic LF(X)显示文摘 | Xu Y Ruan D Kerre E E | 2001 | Infor- mation Sciences2001，132，： | 1 |
| 12 | Central neck lymph node dissection for papillary thyroid cancer:Comparison of complication and recurrence rates in 295 initial dissections and reoperations显示文摘 | Shen WT Ogawa L Ruan D | 2010 | Archives of Surgery2010，145，3： | 1 |
| 13 | Stability of Steady States and Existence of Travelling Waves in a Vector-disease Model 显示文摘 | RUAN S XIAO D | 2004 | Proc Roy Soc Edinburgh Sect A2004，，134： | 1 |
| 14 | Self-tuning of fuzzy belief rule bases for engineering system safety analysis显示文摘 | Liu J Yang J B Ruan D | 2008 | Annals Operational Research2008，163，： | 1 |
| 15 | A current gain model of SiGe HBT for low temperature and various Ge fraction profiles 显示文摘 | WANG D Q RUAN G XUE L C | 1999 | Resear & Progress Sol Sta Elee1999，19，2： | 1 |
| 16 | Observation of enhanced raman scattering for molecules adsorbed on TiO2 nanoparticles:charge-transfer contribution显示文摘 | YANG L B JIANG X RUAN W D | | 0，，50： | 1 |
| 17 | PRM1 variant rs35576928 (Arg > Ser) is associated with defective spermatogenesis in the Chinese Han population 显示文摘 | He X J Ruan J Du W D | 2012 | Reprod B iomed Online2012，25，6： | 1 |
| 18 | Pesttranslafional elevation of cell wall in- vertase activity by silencing its inhibitor in tomato delays leaf senes- cence and increases seed weight and fruit bexese level 显示文摘 | Jin Y Ni D A Ruan Y L | 2009 | Plant Cell2009，21，7： | 1 |
| 19 | Relationship between syphilis and HIV infections among men who have sex with men in Beijing, China 显示文摘 | Ruan Y Li D Li X | 2007 | Sex Transm Dis2007，34，8： | 1 |
| 20 | Age-related morphological impairments in the rat hippocampus following developmental lead exposure: An MRI, LM and EM study显示文摘 | Meng X M Ruan D Y Kang L L | 2003 | Envir Toxicol Pharmacol2003，13，： | 1 |
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