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26篇 您的检索式:作者名="Rui Cruz"
    题名 作者 年代 出处 被引量
1Animal models of acute gastric mucosal injury: Macroscopic and microscopic evaluation显示文摘Acute gastric mucosal injury is a common disorder of the gastrointestinal tract and the search for new therapeutics is ongoing. The aim of this study is to update and expand the information related to the most widely used rat models of acute gastric ulcer, the ethanol‐induced ulcer and the indomethacin‐induced ulcer. These two models are compared in terms of macroscopic and microscopic features. Experimentally, ethanol was given orally in a single dose and indomethacin was subcutaneously injected into male Wistar rats. After ulcerative challenges, the stomachs were removed and visually inspected. Anti‐ulcerative drugs were used to validate the models. Histological analysis of the stomachs determined the microscopic score. The methodology used for model evaluation applied to macroscopic and microscopic gastric lesions. With these methods it was possible to induce lesions in the gastric mucosa. Microscopic evaluation permitted assessment of the inflammatory and apoptotic impact in the mucosa not observable by macroscopic evaluation. Groups of animals were treated with two standard drugs: sulcralfate suspension or lansoprazole solution. Both drugs reduced macroscopic and microscopic lesions, particularly the hemorrhagic ones. Both models induced acute gastric mucosal injury and no single evaluation method can address all the aspects of the pathology of gastric lesions. As a complement to macroscopic evaluation, microscopy appears to be a relevant tool to selectively identify specific aspects of the development of mucosal injury, quantify the extent of lesions, and contribute to an appropriate interpretation of results. The score systems established here offer a reliable method for testing antiulcer drugs.Sandra Simoes Rui Lopes Maria Celeste Dias Campos Maria Joao Marruz Maria Eugenia Meirinhos da Cruz Luisa Corvo 2019Animal Models and Experimental Medicine2019,2,2:7
2Biodiesel compatibility with carbon steel and HDPE parts显示文摘Marcia Marie Maru Marcia Maria Lucchese Cristiano Legnani Welber Gianini Quirino Andrea Balbo Isabele Bulh?es Aranha Lílian Terezinha Costa Cecília Vilani Lídia ágata de Sena Jailton Carreteiro Damasceno Talita dos Santos Cruz Leandro Reis Lidízio Rui Fer 2009Fuel Processing Technology2009,,9:1
3Experimental Behavior of End-plate Beam-to-column Composite Joints Under Monotonical Loading显示文摘 Rui D Simoes Paulo J S Cruz 2001Engineering Structures2001,23,11:1
4Effect of cold chain temperature abuses on the quality of frozen watercress显示文摘Cruz Rui M S Vieira Margarida C Silva Cristina L M 2003Journal of Food Engineering2003,60,1:1
5Effect of heat and thermosonication treatments on peroxidase inactivation kinetics in watercress (Nasturtium officinale) 显示文摘Rui M S Cruz Margarida C Vieira Cristina L M 2006Journal of Food Engineering2006,72,:1
6Effect of heat and thermosonication treatments on peroxidase inactivation kinetics in watercress (Nasturtium officinale)显示文摘Rui M S Cruz Margarida C Vieira Cristina L M Silva 0,,:1
7Impacto da idade no tratamento e resultados após enfarte agudo do miocárdio em particular nos muito idosos显示文摘Ana Teresa Timóteo Ruben Ramos Alexandra Toste Ana Lousinha José Alberto Oliveira Maria Lurdes Ferreira Rui Cruz Ferreira 2011Revista Portuguesa de Cardiologia2011,,12:1
8Effect of heat and thermosonication treatments on peroxidase inactivation kinetics in watercress (Nasturtium officinale) 显示文摘Rui M S Cruz Margarida C Vieira Cristina L M Silva 2006Journal of Food Engineering2006,72,:1
9Modeling kinetics of watercress (Nasturtium officinale) color changes due to heat and thermosonication treatments显示文摘Rui M S Cruz Margarida C Vieira Cristina L M Silva 2007Innovative Food Science & Emerging Technologies2007,,8:1
10Flexible Contracts to Cope with Uncertainty in Public-private Partnerships显示文摘Carlos Oliveira Cruz Rui Cunha Marques 2013International Journal of Project Management2013,,31:1
11Economic cost recovery in the recycling of packaging waste: the case of Portugal显示文摘Nuno Ferreira da Cruz Pedro Simoes Rui Cunha Marques 2012Journal of Cleaner Production2012,37,:1
12Experimental Behavior of End-plate Beam-to-column Composite Joints Under Monotonical Loading显示文摘Simoes da Silva L Rui D Simoes Paulo J S Cruz 2001Engineering Structures2001,23,11:1
13Flexible contracts to cope with uncertainty in public–private partnerships显示文摘Carlos Oliveira Cruz Rui Cunha Marques 2012International Journal of Project Management2012,,:1
14Flexible contracts to cope with uncertainty in Public-Private Partnerships显示文摘Carlos Oliveira Cruz A Rui Ckmha Marques 2013International Journal of Project Management2013,,7:1
15Effect of heat and thermosonication treatments on peroxidase inactivation kinetics in watercress (Nasturtium officinale) 显示文摘Rui M S Cruz Margarida C Vieira Cristina L M Silva 2006Journal of Food Engineering2006,72,:1
16Flexible contracts to cope with uncertainty in public–private partnerships显示文摘Carlos Oliveira Cruz Rui Cunha Marques 2012International Journal of Project Management2012,,:1
17Modeling kinetics of watercress (Nasturtium officinale) color changes due to heat and thermosonication treatments显示文摘Rui M S Cruz Margarida C Vieira Cristina L M Silva 2007Innovative Food Science & Emerging Technologies2007,,8:1
18Physico -mechanical properties of chitosan films with carvacroland grape seed extract 显示文摘Rubilar Javiera F Cruz Rui MS Silva Helder D 2012Journal of Food Engineering2012,115,4:1
19Effect of heat and thermosonication treatments on peroxidase inactivation kinetics in watercress (Nasturtium officinale)显示文摘Rui M S Cruz Margarida C Vieira Cristina L M Silva 2006Journal of food Engineering2006,72,:1
20Thrombus Formation on a Left Atrial Appendage Closure Device显示文摘Lorette Cardona Galrinho Ana Branco Luísa Ana Leal Fiarresga António Sousa Lídia Ferreira Rui Cruz 2011Circulation2011,,14:1
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