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1Endoscopic ultrasonography for gastric submucosal lesions显示文摘Gastric submucosal tumors(SMTs) are a rather frequent finding,occurring in about 0.36%of routine upper GIendoscopies.Endoscopic ultrasonography(EUS) has emerged as a reliable investigative procedure for evaluation of these lesions.Diagnostic EUS has the ability to differentiate intramural tumors from extraluminal compressions and can also show the layer of origin of gastric SMTs.Tumors can be further characterized by their layer of origin,echo pattern and margin.EUS-risk criteria of their malignant potential are presented,although the emergence of EUS-FNA has opened new indications for transmural tissue diagnosis and expanded the possibilities of EUS in SMTs of the stomach.Tissue diagnosis should address whether the SMT is a Gastrointestinal stromal tumour(GIST) or another tumor type and evaluate the malignant potential of a given GIST.However,there seems to be a lack of data on the optimal strategy in SMTs suspected to be GISTs with a negative EUS-FNA tissue diagnosis.The current management strategies,as well as open questions regarding their treatment are also presented.Ioannis S Papanikolaou Konstantinos Triantafyllou Anastasia Kourikou Thomas Rsch 2011World Journal of Gastrointestinal Endoscopy2011,3,5:44
2肠道菌群促进血管紧张素Ⅱ诱导的高血压和血管功能障碍显示文摘肠道微生物对宿主生理反应及对免疫功能的发展来说必不可少。肠道菌群对血压和全身血管功能等这些由免疫细胞功能决定的生理过程的影响知之甚少。方法:与常规饲养的小鼠(conventionally raised rats,CONV-R)比较,未受任何细菌影响的无菌小鼠(GF)表现出较为严重的全身性辅助性T细胞1型滞后。刘莉 叶鹏 Karbach SH Schnfelder T Brandao I Wilms E Hrmann N Jckel S Schüler R Finger S Knorr M Lagrange J Brandt M Waisman A Kossmann S Schüfer K Münzel T Reinhardt C Wenzel P 2016中华高血压杂志2016,24,10:5
3Adiponectin and its receptors in rodent models of fatty liver disease and liver cirrhosis显示文摘AIM: To determine circulating and hepatic adiponectin in rodents with fatty liver disease or liver cirrhosis and investigate expression of the adiponectin receptors AdipoR1 on the mRNA and protein level and AdipoR2 on the mRNA level. METHODS: Fat fed rats were used as a model for fatty liver disease and bile duct ligation in mice to investigate cirrhotic liver. Expression of AdipoR1 and AdipoR2 mRNA was determined by real time RT-PCR. AdipoR1 protein was analysed by immunoblot. Adiponectin was measured by ELISA. RESULTS: Systemic adiponectin is reduced in fat- fed rats but is elevated in mice after bile duct ligation (BDL). Hepatic adiponectin protein is lower in steatotic liver but not in the liver of BDL-mice when compared to controls. Adiponectin mRNA was not detected in human liver samples or primary human hepatocytes nor in rat liver but recombinant adiponectin is taken up by isolated hepatocytes in-vitro. AdipoR1 mRNA and AdipoR1 protein levels are similar in the liver tissue of control and fat fed animals whereas AdipoR2 mRNA is induced. AdipoR2 mRNA and AdipoR1 mRNA and protein is suppressed in the liver of BDL-mice. CONCLUSION: Our studies show reduced circulating adiponectin in a rat model of fatty liver disease whereas circulating adiponectin is elevated in a mouse model of cirrhosis and similar fi ndings have been described in humans. Diminished hepatic expression of adiponectinreceptors was only found in liver cirrhosis.Markus Neumeier Claus Hellerbrand Erwin Gbele Roland Buettner Cornelius Bollheimer Johanna Weigert Andreas Schffler Thomas S Weiss Monika Lichtenauer Jürgen Schlmerich Christa Buechler 2006World Journal of Gastroenterology2006,12,34:4
4Production and stability of 3-hydroxypropionaldehyde in Lactobacillus reuteri显示文摘Lü thi-Peng Q Schrer S Puhan Z 2002Appl Microbiol Biotechnol2002,60,:2
5脑卒中血栓切除术后血压与短期和长期功能转归的相关性显示文摘缺血性脑卒中机械性血栓切除术后的转归可能受血压的影响。该研究旨在评估全身麻醉期间和清醒镇静期间血压变化与机械性血栓切除术后功能性转归的关系。血管内治疗脑卒中的镇静与气管插管研究是一项涉及血压目标值的,比较在全身麻醉与在清醒镇静的条件下行机械血栓切除疗效的单中心随机试验。刘青 叶鹏 Schnenberger S Uhlmann L Ungerer M Pfaff J Nagel S Klose C Bendszus M Wick W Ringleb PA Kieser M Mhlenbruch MA Bsel J 2018中华高血压杂志2018,26,7:2
6Syndromes of Vibrio vulnificus infection clinical and epidemiologic features in Florida cases, 1981 1987 显示文摘Klontz K C L ieb S Sch reiber M 1988Ann Intern Med1988,,:1
7Validierung einer deutsehsprachigen Version des Body Image Avoidance Questionnaire BIAQ显示文摘LEGENBAUER T VOCKS S SCH?TT-STR?MEL S Diagnostiea0,20,53:1
8Interleukin-6 gene knockout influences energy balance regulating peptides in the hypothalamic paraventriculaR and supraoptic nuclei显示文摘Benrick A Schéle E Pinnock S B 2009J Neuroendocrinol2009,21,7:1
9Connexin 50,a gap junction protein of macroglia in the mammalian retina and visual pathway显示文摘Schütte M Chen S Buku A 1998Exp Eye Res1998,66,:1
10Transjugular intrahepatic portosystemic shunt:present status,comparison with endoscopic therapy and shunt surgery,and future prospectives显示文摘J R(O)SCH M D FREDERCK S KELLER M D 2001World J Surg2001,25,:1
11Interaction of the herbicide glyphosate with its target enzyme 5-enolpyruvylshikimate 3-phosphate synthase in atomic detail显示文摘Sch?nbrunn E Eschenburg S Shuttleworth W A 2001PNAS2001,98,4:1
12Revolution in plate osteosynthesis: new internal fixator systems显示文摘Michael Schütz Norbert P. Südkamp 2003Journal of Orthopaedic Science2003,,2:1
13REDIA-impacts of DRG introduction in the acute sector on medical rehabih'tation显示文摘von Eif W Sch ii ring S Greitemann B 2011Die Rehabilitation2011,50,4:1
14The optimal carrier for BMP-2 a comparison of collagen versus fibrin ma-trix显示文摘Schützenberger S Schultz A Hausner T 2012Arch Orthop Trauma Surg2012,132,9:1
15Use of Saccharomyces cerevisiae cells immobilized on orange peel as biocatalyst for alcoholic fermentation显示文摘 Sch B S Coleraine B T 2007Bioresource Technology2007,98,4:1
16Photoactivated phytochrome induces rapid PIF3 phosphorylation prior to proteasome-mediated degradation显示文摘Al-Sady B Ni W Kircher S Sch?fer E Quail P H 2006Molecular cell2006,23,3:1
17Clinical characteristics and time trends in etiology of hepatocellular cancer in Germany显示文摘Schütte K Kipper M Kahl S 0,,:1
18Chain length-specific properties of ceramides显示文摘Gr?sch S Schiffmann S Geisslinger G 2012Prog Lipid Res2012,51,1:1
19Fast determination of histamine in cheese by nuclear magnetic resonance (NMR) 显示文摘Sch ievano E Guardini K Mammi S 2009J Agr Food Chem2009,57,7:1
20HDAC2 mediates therapeutic resistance of pancreatic cancer cells via the BH3-only protein NOXA显示文摘Fritsche P Seidler B Schüler S 2009Gut2009,58,10:1
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