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1IL 28 B genotype is not useful for predicting treatment outcome in A sian chronic hepatitis B patients treated with pegylated interferon‐α显示文摘Jacinta A Holmes Tin Nguyen Dilip Ratnam Neel M Heerasing Jane V Tehan Sara Bonanzinga Anouk Dev Sally Bell Stephen Pianko Robert Chen Kumar Visvanathan Rachel Hammond David Iser Ferry Rusli William Sievert Paul V Desmond D Scott Bowden Alexander J Thomps 2013J Gastroenterol Hepatol2013,,5:2
2Chronic pancreatitis and the heart disease:Still terra incognita?显示文摘BACKGROUND It has been suggested that chronic pancreatitis(CP)may be an independent risk factor for development of cardiovascular disease(CVD).At the same time,it seems that congestive heart failure(CHF)and CP share the responsibility for the development of important clinical conditions such as sarcopenia,cachexia and malnutrition due to development of cardiac cachexia and pancreatic exocrine insufficiency(PEI),respectively.AIM To explore the evidence regarding the association of CP and heart disease,more specifically CVD and CHF.METHODS A systematic search of MEDLINE,Web of Science and Google Scholar was performed by two independent investigators to identify eligible studies where the connection between CP and CVD was investigated.The search was limited to articles in the English language.The last search was run on the 1st of May 2019.The primary outcomes were:(1)Incidence of cardiovascular event[acute coronary syndrome(ACS),chronic coronary disease,peripheral arterial lesions]in patients with established CP;and(2)Incidence of PEI in patients with CHF.RESULTS Out of 1166 studies,only 8 were eligible for this review.Studies regarding PEI and CHF showed an important incidence of PEI as well as associated malabsorption of nutritional markers(vitamin D,selenium,phosphorus,zinc,folic acid,and prealbumin)in patients with CHF.However,after substitution of pancreatic enzymes,it seems that,at least,loss of appetite was attenuated.On the other side,studies investigating cardiovascular events in patients with CP showed that,in CP cohort,there was a 2.5-fold higher incidence of ACS.In another study,patients with alcohol–induced CP with concomitant type 3c diabetes had statistically significant higher incidence of carotid atherosclerotic plaques in comparison to patients with diabetes mellitus of other etiologies.Earlier studies demonstrated a marked correlation between the clinical symptoms in CP and chronic coronary insufficiency.Also,statistically significant higher incidence of arterial lesions was found in patients with CP compared to the control group with the same risk factors for atherosclerosis(hypertension,smoking,dyslipidemia).Moreover,one recent study showed that PEI is significantly associated with the risk of cardiovascular events in patients with CP.CONCLUSION Current evidence implicates a possible association between PEI and malnutrition in patients with CHF.Chronic pancreatic tissue hypoxic injury driven by prolonged splanchnic hypoperfusion is likely to contribute to malnutrition and cachexia in patients with CHF.On the other hand,CP and PEI seem to be an independent risk factor associated with an increased risk of cardiovascular events.Sara Nikolic Ana Dugic Corinna Steiner Apostolos V Tsolakis Ida Marie Haugen Lofman J-Matthias Lohr Miroslav Vujasinovic 2019World Journal of Gastroenterology2019,25,44:2
3Somatomedins in aging and in dementia of the Alzheimer type显示文摘SARA V R HALL K ENZELL K 1982Neurobiol Aging1982,3,2:1
4Biological recycling of used baby diapers in a small-scale composting system显示文摘Rosa M. Espinosa-Valdemar Perla X. Sotelo-Navarro Xochitl Quecholac-Pi?a Mariel A. García-Rivera Margarita Beltrán-Villavicencio Sara Ojeda-Benítez Alethia Vázquez-Morillas 2014Resources, Conservation & Recycling2014,,:1
5Combination of multiplex PCR and PCR-denaturing gradient gel electrophoresis for monitoring common sourdough-associated Lactobacillus species显示文摘Luca S Sara V Douwe van S 2006Appl Environ Microbiol2006,72,5:1
6Chemical routes for the transformation of biomass into chemicals 显示文摘Avelino C Sara I Alexandra V 2007Chem Rev2007,107,6:1
7Role of alpha/beta interferons in the attenuation and immunogenicity of recombi nant bovine respiratory syncytial viruses lacking NS proteins显示文摘Jean F V Julie F Sara W 2003Virolology2003,77,15:1
8A review of Maillard reaction in food and implications to kinetic modeling显示文摘Sara I M Wim M J Martinus A V B 2000Trends in Food Science and Technology2000,11,9:1
9Vanilloid re- ceptor agonists and antagonists are mitochondrial inhibitors: How vanilloids cause nonvanilloid re- ceptor mediated cell death 显示文摘Andriani A Paul AS Sara V 2007Biochem Biophys Res Commun2007,354,1:1
10Determination of anions in rainwater by capillary electrophoresis with conductivity detection显示文摘Sara V Gianni T Stefano P 1997J Chromatogr A1997,760,2:1
11Ara h 2peptides containing dominant CD4+T-cell epitopes:Candidates for a peanut allergy therapeutic显示文摘Sara R P Astrid L V April D H Karen S 2011J Allergy Clin Immunol2011,127,:1
12Chemical routes for the transformation of biomass into chemicals 显示文摘AVELINO C SARA I ALEXANDRA V 2007ChemRev2007,46,38:1
13Chemical routes for the transformation of biomass into chemicals显示文摘Avelino C Sara I Alexandra V 2007Chem Rev2007,107,:1
14Activin a induces Langerha-ns cell differentiation in vitro and in human skin explants显示文摘Tiziana M Sara S William V 2008PLoS ONE2008,3,9:1
15Composition Dependence of the Electrical Conductivity of Se(85-x)Te(15)Sbx(x=2,4,6,8 and 10)Glass at Room Temperature显示文摘Sara swat V K Singh K Saxena N S 2006Current Applied Physics2006,6,:1
16Hollow capsules formed in a single stage via interfacial hydrogenonded complexation of methylcellulose with poly (acrylic acid) and tannicacid显示文摘Krystie Driver Sara Baco Vitaliy V Khutoryans- kiy 2013European Polymer Journal2013,49,12:1
17Comparison of chest to- mosynthesis and chest radiography for detection of pulmonary nodules:human observer study of clinical cases显示文摘Jenny V Sara Z Angelica S 2008Radi- ology2008,249,3:1
18Bovine ineteferon agenes structure and expression显示文摘Baruch V Sara C Haim G 1985The Journal of Biological chemistry1985,260,9:1
19Synthesis and inhibitory activity of thymidine analogues targeting mycobacterium tuberculosis thymidine monophosphate kinase显示文摘Sara V P Helene M L Olivier H 0,,19:1
20Advanced superplastic forming and diffusion bonding of titanium alloy显示文摘KAIBYSHEV 0 A SAFIULLIN R V LUTFULLIN R Y VALIAKHMETOV 0 R GALEYEV R M DUTTA A RAGHU T SARA G G 2006Materials Science and Technology2006,22,3:1
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