|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 柯柯牙城郊防护林主要造林类型土壤改良效应研究显示文摘城郊防护林作为城市的生态基础设施为城市及其居民持续获得自然生态服务提供保障.本文对新疆南部典型绿洲城市——阿克苏市郊柯柯牙人工防护林工程的土壤修复与改良效应进行定量研究,以该地区4种不同造林类型(红枣林、香梨林、苹果林和杨树林)土壤为研究对象,实测观察其土壤理化性质及其垂直分布变化,对比分析4种林型下土壤不同因子的差异及各因子间的相关性,揭示了人工防护林建设对裸露沙地土壤的综合改良效应.结果表明:(1)人工造林使原沙地土壤物理结构得以改善、土壤水分大幅提升、p H值和可溶性盐含量有效降低、土壤有机质和养分含量显著提高;(2)红枣林地土壤物理改良效果最为明显,对于可溶性盐而言,杨树林地土壤含盐量最低,经济(果园)林地呈现中层土壤(10~30 cm)高于表层和底层土壤的规律,体现了人工漫灌的'压盐'作用;(3)各林型对土壤化学因子改良效果存在差异,土壤各因子之间存在着较为显著的相关性;改良后的土壤质量优劣程度排序为:苹果林地>红枣林地>香梨林地>杨树林地. | 玉米提.哈力克 塔依尔江.艾山 张利霞 阿布都拉.阿不力孜 Martin Welp Siegmund Missall | 2015 | 新疆大学学报(自然科学版)2015，32，3： | 9 |
| 2 | Innate and adaptive immunity in inflammatory bowel disease显示文摘Inflammatory bowel diseases are the consequence of a dysregulated mucosal immune system. The mucosal immune system consists of two arms, innate and adaptive immunity, that have been studied separately for a long time. Functional studies from in vivo models of intestinal inflammation as well as results from genome-wide association studies strongly suggest a crossregulation of both arms. The present review will illustrate this interaction by selecting examples from innate immunity and adaptive immunity, and their direct impact on each other. Broadening our view by focusing on the cross-regulated areas of the mucosal immune system will not only facilitate our understanding of disease, but furthermore will allow identification of future therapeutic targets. | Britta Siegmund Martin Zeitz | 2011 | World Journal of Gastroenterology2011，17，27： | 9 |
| 3 | Enhanced expression of interleukin-18 in serum and pancreas of patients with chronic pancreatitis显示文摘AIM: To investigate interleukin-18 (IL-18) in patients with chronic panreatitis (CP). METHODS: We studied 29 patients with CP and 30 healthy controls. Peripheral blood mononuclear cells (PBMC) were isolated and incubated with 50 mmol/L ethanol, lipopolysaccharide (LPS) (doses 25 g/L, 250 g/L, 2500 g/L) and both agents for 24 h. Levels of IL-18 in the supernatants, and levels of IL-18, IL-12, interferon (IFN)-γ and soluble CD14 in the serum were analysed by ELISA technique. Expression of IL-18 in PBMC was investigated by reverse-transcription (RT)-PCR. IL-18 protein levels in CP tissue and in normal pancreas were studied by ELISA technique. IL-18 levels in PBMC and pancreatic tissue were determined by Westernblot. Im-munohistochemistry for pancreatic IL-18 expression was performed. RESULTS: In patients, IL-18 serum levels were signifi-cantly enhanced by 76% (mean: 289.9 ± 167.7 ng/L) compared with controls (mean: 165.2 ± 43.6 ng/L; P < 0.0005). IL-12 levels were enhanced by 25% in patients (18.3 ± 7.3 ng/L) compared with controls (14.7 ± 6.8ng/L, P = 0.0576) although not reaching the statistical significance. IFN-γ and soluble CD14 levels were not in-creased. In vitro, LPS stimulated significantly and dose-dependently IL-18 secretion from PBMC. Incubation with ethanol reduced LPS-stimulated IL-18 secretion by about 50%. The mRNA expression of IL-18 in PBMC and the response of PBMC to ethanol and LPS was similar in CP patients and controls. In PBMC, no significant differences in IL-18 protein levels were detected between patients and controls. IL-18 protein levels were increased in CP tissues compared to normal pancreatic tissues. IL-18 was expressed by pancreatic acinar cells and by infiltrating inflammatory cells within the pancreas. CONCLUSION: IL-18 originates from the chronically inflammed pancreas and appears to be involved in the fibrotic destruction of the organ. | Alexander Schneider Stephan L Haas Ralf Hildenbrand Sren Siegmund Iris Reinhard Helmut Nakovics Manfred V Singer Peter Feick | 2006 | World Journal of Gastroenterology2006，12，40： | 4 |
| 4 | Extraluminal factors contributing to inflammatory bowel disease显示文摘Many identified and yet unknown factors contribute to the pathogenesis of inflammatory bowel disease(IBD).The genome-wide association studies clearly support the earlier developed concept that IBD occurs in genetically predisposed individuals who are exposed to distinct environmental factors,which together result in dysregulation of the mucosal immune system.Thus,the majority of previous studies have focused on the immune response within the intestinal wall.The present review aims to emphasize the contribution of three extraluminal structures to this inflammatory process,namely the mesenteric fat tissue,the lymphatics and the microvasculature.Broadening our view across the intestinal wall will not only facilitate our understanding of the disease,but will also us to identify future therapeutic targets. | Arvind Batra Thorsten Stroh Britta Siegmund | 2011 | World Journal of Gastroenterology2011，17，5： | 3 |
| 5 | 胰岛素笔薄壁针头与常规针头的实用性及患者的使用偏好比较显示文摘一项多中心、开放标签、无对照研究纳入了97名使用胰岛素笔注射治疗的糖尿病患者,旨在评估患者对胰岛素笔的使用习惯以及患者对31号薄壁针头和常规针头的评价。患者进行2次为期2周的治疗,第一次使用常规针头,第二次用薄壁针头,而后填写调查问卷。97名患者(女性占48%,年龄20~70岁,平均56岁)全部完成问卷调查。 | Siegmund T Blankenfeld H Schumm-Draeger PM | 2009 | 药品评价2009，6，10： | 2 |
| 6 | 统计学:二十一世纪的挑战和机遇(Ⅲ)显示文摘 | Bruce Lindsay Jon Kettenring David Siegmund 缪柏其 | 2005 | 数理统计与管理2005，24，5： | 2 |
| 7 | 统计学:二十一世纪的挑战和机遇(Ⅳ)显示文摘 | Bruce Lindsay Jon Kettenring David Siegmund 缪柏其 | 2005 | 数理统计与管理2005，24，6： | 2 |
| 8 | HLA-DMA and HLA-DMB alleles in German patients with type I diabetes mellitus显示文摘 | Siegmund T Donner H Braun J | 1999 | Tissue Antigens1999，54，3： | 1 |
| 9 | Correlation of heavy-truck driver fatigue with vehicle-based control measures显示文摘 | SIEGMUND G P KING D J MUMFORD D K | 1995 | SAE Paper 9525941995，，： | 1 |
| 10 | Cervical muscle response during whiplash: evidence of a lengthening muscle contraction显示文摘 | BRAULT JR SIEGMUND GP WHEELER JB | 2000 | Clin Biomech(Bristol Avon)2000，15，： | 1 |
| 11 | CpG island methylator phenotype underlies sporadic mi- crosatellite instability and is tightly associated with BRAF mu- tation in colorectal cancer显示文摘 | WEISENBERGER D J SIEGMUND K D CAMPAN M | 2006 | Nature Genetics2006，38，7： | 1 |
| 12 | Memory impairment correlates with increased S100B serum concentrations in patients with chronic schizophrenia显示文摘 | Anya Pedersen Markus Diedrich Florian Kaestner Katja Koelkebeck Patricia Ohrmann Gerald Ponath Frank Kipp Simone Abel Ansgar Siegmund Thomas Suslow Christof von Eiff Volker Arolt Matthias Rothermundt | 2008 | Progress in Neuropsychopharmacology & Biological Psychiatry2008，，： | 1 |
| 13 | Neutrophil-independent mechanisms of caspase-1-and IL-18-mediated ischemic acute tubular necrosis in mice显示文摘 | Melnikov VY Faubel S Siegmund B | 2002 | J Clin Inves2002，110，8： | 1 |
| 14 | Die diagnostische Validit?t nichtinvasiver Pankreasfunktionstests - Eine Metaanalyse显示文摘 | E Siegmund J L?hr P Schuff-Werner | 2004 | Z Gastroenterol2004，，10： | 1 |
| 15 | Chemical and sensory effects of glass and laminated carton packages on fruit juice products- still a controversial topic 显示文摘 | Siegmund B Derler K Pfannhauser W | 2004 | LWT- Food Science and Technology2004，37，： | 1 |
| 16 | Odor thresholds of microbially induced off-flavor compounds in apple juice显示文摘 | Siegmund B Pfillinger-zierler B | 2006 | J Agric Food Chem2006，54，： | 1 |
| 17 | Residue levels of ethyl carbamate in wines and spirits by gas chromatography and mass spectrometry/mass spectrometry显示文摘 | Cairns T Siegmund EG Luke MA | 1987 | Analytical Chemistry1987，59，17： | 1 |
| 18 | DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons显示文摘 | Siegmund K D Connor C M Campan M | 2007 | PLoS One2007，2，9： | 1 |
| 19 | Longevity of adult ventricular rat heart muscle cells in serum-free primary culture显示文摘 | Piper HM Siegmund B | 1991 | J Mol Cell Cardiol1991，23，： | 1 |
| 20 | Biological anphiphiles(microbial biosurfactants)显示文摘 | Siegmund Lang | 2002 | Current Opinion in Colloid & Interface Science2002，，7： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员