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| 1 | Silent diabetic nephropathy显示文摘AIM: To examine the risk of renal events in patients with biopsy-proven diabetic nephropathy(DN) and its possible associated factors.METHODS: Clinical and histological data of 60 patients diagnosed with diabetic nephropathy were retrospectively collected. Patients with evidence or suspicion of other nephropathies were excluded from the study. The final event was defined as renal replacement therapy(RRT) initiation or progression of chronic kidney disease(CKD), according to the KDIGO 2012 definition of a decrease in CKD category and a decrease in GFR of 25% or more. RESULTS: A total of 45 patients with a follow-up of at least 3 mo were included. Most of the patients presented type 2 DM, with a median age of 58.3 years old. The time of evolution of DM was 9.6 ± 7.8 years, although in 13 patients, it was less than 5 years. A total of 62% of patients reached the final event in a mean period of 3.4 years(95%CI: 2.1-4.7), with 21 of them requiring dialysis. The factors that were independently associated with renal survival were estimated glomerular filtration rate(e GFR) at the time of biopsy, cardiovascular disease(CVD) history and Hb A1 c less than 7%. Therefore, for each 10 m L/min per 1.73 m2 reduction in e GFR, we obtained a DN progression risk of HR = 2(1.3-3.0)(P = 0.001); patients with CVD were at greater risk for DN progression(HR = 2.8, 1.1-7.1, P = 0.032), and CKD patients with Hb A1 c < 7% demonstrated greater renal risk than patients with Hb A1 c ≥ 7%, with an HR of 2.9(1.0-8.4)(P = 0.054).CONCLUSION: A past history of CVD is a risk factor for DN progression. Levels of Hb A1 c less than 7% could favor an e GFR decrease in these patients. | Katia López-Revuelta Patricia Pea Galdo Ramona Stanescu Leticia Parejo Carmen Guerrero Elia Pérez-Fernández | 2014 | World Journal of Nephrology2014，3，1： | 2 |
| 2 | The Optimal Spacing Between Horizontal Cylinders in a Fixed Volume Cooled by Natural Convection 显示文摘 | Bejan A Fowler A J Stanescu G | 1995 | International Journal of Heat and Mass Transfer1995，38，11： | 1 |
| 3 | Risk HLA -DQAI and PLA(2) R1 alleles in idiopathic membranous ne phropathy显示文摘 | Stanescu HC Arcos - Burgos M Medlar A | 2011 | N Engl J Med2011，364，7： | 1 |
| 4 | Airways obstruc- tion, chronic expecto - ration, and rapid decline of FEV1 in smokers are associated with increased levels of sputum neu- trophils显示文摘 | Stanescu D Sanna A Veriter C | 1996 | Thorax1996，1，3： | 1 |
| 5 | Airways obstruction, chronic ex-pectoration and rapid decline of FEV 1 in smokers are associated with in-creased levels of sputum neutrophils显示文摘 | Stanescu D Sanna A Venter C | 1996 | Thorax1996，51，1： | 1 |
| 6 | Constitutive overexpression of human erythropoietin protects the mouse retina against induced but not inherited retinal degeneration显示文摘 | Grimm C Wenzel A Stanescu D | 2004 | J Neurosci2004，24，： | 1 |
| 7 | Preparation and properties of novel slow-release NPK agroehemical formulations based on poly (acrylic acid ) hydrogels and liquid fertilizers 显示文摘 | Teodorescu M Lungu A Stanescu P O Neamt C | 2009 | Industrial Engineering Chemistry Research2009，48，14： | 1 |
| 8 | Risk HLA- DQA1 and PLA (2)R I alleles in idiopathic membranous ne- phropathy显示文摘 | Stanescu HC ArcoBurgos M Medlar A | 2011 | N Engl J Med2011，364，61： | 1 |
| 9 | Chronic erosive gastritis - a therapeutic approach with bismuth显示文摘 | Malfertheiner P Stanescu A Baczakod | 1988 | Scand J Gastroenterol1988，142，： | 1 |
| 10 | The optimal spacing between horizontal cylinders in a fixed volume cooled by natural convection 显示文摘 | FOWLER A J Stanescu G | 1995 | Int J Heat Mass Trans1995，38，3： | 1 |
| 11 | Diagnostic errors inpolytrauma: a structured review of the recent literature 显示文摘 | Stanescu L Talner L B Mann F A | 2006 | Emerg Radiol2006，12，3： | 1 |
| 12 | Preparation and prop- erties of novel slow-release NPK agrochemical formulations based on poly( acrylic acid)hydrogels and liquid fertilizers显示文摘 | Teodorescu M Lungu A Stanescu P O | 2009 | Ind Eng Chem Res2009，48，14： | 1 |
| 13 | Airwayobstruc-tion,chronic expectoration,and rapid decline of FEV1in smokers are associated with increased levelsof spu-tum neutrophils显示文摘 | Stanescu D Sanna A Veriter C | 1996 | Thorax1996，51，3： | 1 |
| 14 | Risk HLA-DQA1 and PLA (2) RI alleles in idiopathic membranous nephropathy 显示文摘 | Stanescu HC Areos-Burgos M Medlar A | 2011 | N Engl J Med2011，364，7： | 1 |
| 15 | Constitutive overexpression of human erythropoietin protects the mouse retina against induced but not inherited retinal degeneration显示文摘 | Wenzel A Stanescu D | 2004 | J Neurosci2004，24，： | 1 |
| 16 | Constitutive overexpression of human erythropoietin protects the mouse retina against induced but not inherited retinal degeneration显示文摘 | Grimm C Wenzel A Stanescu D Samardzija M Hotop S Groszer M | 2004 | J Neurosci2004，24，25： | 1 |
| 17 | On Hopf-Galois extensions of linear categories 显示文摘 | Stanescu A | 2012 | Analele Universitatii 'Ovidius' Constanta-Seria Mathematica2012，20，3： | 1 |
| 18 | Airways obstruction, chronic expectoration, and rapid decline of FEV1 in smokers are associated with increased levels of sputum neutrophils 显示文摘 | Stanescu D Sanna A Veriter C | 1996 | Thorax1996，51，3： | 1 |
| 19 | Constitutive over expression of human erythropoietin protects the mouse retina against induced but not inherited retinal degene- ration显示文摘 | Grimm C Wenzel A Stanescu D | 2004 | J Neurosei2004，24，25： | 1 |
| 20 | Anatomic relationships of the cervicothoracic junction 显示文摘 | Bailey A Stanescu S Yeasting R Ebraheim N Jackson T | 1995 | Spine1995，20，： | 1 |
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