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| 1 | Liver surgery in cirrhosis and portal hypertension显示文摘The prevalence of hepatic cirrhosis in Europe and the United States, currently 250 patients per 100000 inhabitants, is steadily increasing. Thus, we observe a significant increase in patients with cirrhosis and portal hypertension needing liver resections for primary ormetastatic lesions. However, extended liver resections in patients with underlying hepatic cirrhosis and portal hypertension still represent a medical challenge in regard to perioperative morbidity, surgical management and postoperative outcome. The Barcelona Clinic Liver Cancer classification recommends to restrict curative liver resections for hepatocellular carcinoma in cirrhotic patients to early tumor stages in patients with Child A cirrhosis not showing portal hypertension. However, during the last two decades, relevant improvements in preoperative diagnostic, perioperative hepatologic and intensive care management as well as in surgical techniques during hepatic resections have rendered even extended liver resections in higher-degree cirrhotic patients with portal hypertension possible. However, there are few standard indications for hepatic resections in cirrhotic patients and risk stratifications have to be performed in an interdisciplinary setting for each individual patient. We here review the indications, the preoperative risk-stratifications, the morbidity and the mortality of extended resections for primary and metastatic lesions in cirrhotic livers. Furthermore, we provide a review of literature on perioperative management in cirrhotic patients needing extrahepatic abdominal surgery and an overview of surgical options in the treatment of hepatic cirrhosis. | Christina Hackl Hans J Schlitt Philipp Renner Sven A Lang | 2016 | World Journal of Gastroenterology2016，22，9： | 21 |
| 2 | Role of autophagy in the pathophysiology of nonalcoholic fatty liver disease:A controversial issue显示文摘Autophagy is a mechanism involved in cellular homeostasis under basal and stressed conditions delivering cytoplasmic content to the lysosomes for degradation to macronutrients.The potential role of autophagy in disease is increasingly recognised and investigated in the last decade.Nowadays it is commonly accepted that autophagy plays a role in the hepatic lipid metabolism.Hence,dysfunction of autophagy may be an underlying cause of non-alcoholic fatty liver disease.However,controversy of the exact role of autophagy in the lipid metabolism exists:some publications report a lipolytic function of autophagy,whereas others claim a lipogenic function.This review aims to give an update of the present knowledge on autophagy in the hepatic lipid metabolism,hepatic insulin resistance,steatohepatitis and hepatic fibrogenesis. | Wilhelmus J Kwanten Wim Martinet Peter P Michielsen Sven M Francque | 2014 | World Journal of Gastroenterology2014，20，23： | 17 |
| 3 | Ultrasound Doppler system for two-dimensional flow mapping in liquid metals显示文摘 | Sven Franke Lars Büttner Jürgen Czarske Dirk R?biger Sven Eckert | 2010 | Flow Measurement and Instrumentation2010，，3： | 3 |
| 4 | Ecological indicators for assessing freshwater ecosystem health显示文摘 | Fu-Liu Xu Sven Erik J?rgensen Shu Tao | 1999 | Ecological Modelling1999，，1： | 2 |
| 5 | Landscape change detection of the newly created wetland in Yellow River Delta显示文摘 | Tian Xiang Yue Ji Yuan Liu Sven Erik J?rgensen Qin Hua Ye | 2003 | Ecological Modelling2003，，1： | 1 |
| 6 | Impact of interleukin-6 classic- and trans-signaling on liver damage and regeneration显示文摘 | Claudia Drucker Jessica Gewiese Sven Malchow Jürgen Scheller Stefan Rose-John | 2009 | Journal of Autoimmunity2009，，1： | 1 |
| 7 | Acid potentiation of the capsaicin receptor determined by a key extracelluar site显示文摘 | Sven EJ Makoto T David J | 2000 | PNAS2000，97，14： | 1 |
| 8 | Both Local Anesthetics and Salbutamol Pretreatment Affect Reflex Bronchoconstriction in Volunteers with Asthma undergoing Awake Fiberoptic Intubation显示文摘 | Harald Groeben Markus Schlicht Sven Stieglitz Goran Pavlakovic Jürgen Peters | 2002 | Anesthesiology2002，，6： | 1 |
| 9 | Soil and plant C02 emission in response to variations in soil moisture and temperature and to amendment with nitrogen phosphorus and carbon in Northern Scandinavia 显示文摘 | Lontee I Sven J | 1999 | Arctic Antarctic and Alpine1999，31，3： | 1 |
| 10 | High-efficiency coal-fired power plants development and perspectives显示文摘 | J?rgen Bugge Sven Kj?r Rudolph Blum | 2005 | Energy2005，，10： | 1 |
| 11 | Potential impact of climatic change on the distribution of forest herbs in Europe显示文摘 | Skov F Svenning J C | 2004 | Ecography2004，27，： | 1 |
| 12 | Modelling of point and non-point nutrient loadings from a watershed显示文摘 | Zhang Jingjie Sven E J | 2005 | Environmental Modelling & Software2005，20，： | 1 |
| 13 | CXCR4 nanobodies (VHH-based single variable domains) potently inhibit chemotaxis and HIV-1 replication and mobilize stem cells显示文摘 | Sven J Christophe B David M | | 0，，： | 1 |
| 14 | Tissue-specific expression patterns of the RAGE receptor and its soluble forms—a result of regulated alternative splicing?显示文摘 | Claudia Schlueter Sven Hauke Aljoscha M. Flohr Piere Rogalla J?rn Bullerdiek | 2003 | BBA - Gene Structure and Expression2003，，1： | 1 |
| 15 | Effects of Whole-Body Vibration Exercise on Lower-Extremity Muscle Strength and Power in an Older Population: A Randomized Clinical Trial显示文摘 | Rees Sven S Murphy Aron J Watsford Mark L | 2008 | Physical Therapy2008，，4： | 1 |
| 16 | Sacral Neuromodulation for Neurogenic Lower Urinary Tract Dysfunction: Systematic Review and Meta-analysis显示文摘 | Thomas M. Kessler David La Framboise Sven Trelle Clare J. Fowler Gustav Kiss Jürgen Pannek Brigitte Schurch Karl-Dietrich Sievert Daniel S. Engeler | 2010 | European Urology2010，，6： | 1 |
| 17 | Genetic A nalysis Reveals That C19-GA 2-Oxidation Is a Major Gibber ellin Inactivation Pathway in Arabidopsis显示文摘 | Ivo Rieu Sven Eriksson Stephen J Powers | 2008 | The Plant Cell2008，20，： | 1 |
| 18 | Nerve growth factor and its precursor differentially regulate hair cycle progression in mice 显示文摘 | Eva M J Sven H Greta G | 2006 | J Histoehem Cytochem2006，54，3： | 1 |
| 19 | Resource allocation in relation to leaf retention time of the wintergreen Rhododendron lapponcum显示文摘 | Sven J | 1995 | Ecology1995，76，2： | 1 |
| 20 | Excision of thrombosed external hemorrhoid under local anesthesia显示文摘 | Johannes J Sebastian B Sven HS | 2003 | Dis Colon Rectum2003，46，9： | 1 |
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