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| 1 | Efficacy of intramuscular diclofenac and fluid replacement in prevention of post-ERCP pancreatitis显示文摘AIM:To assess the efficacy of intramuscular diclofenac and fluid replacement for prevention of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis.METHODS: A prospective, placebo-controlled study was conducted in 80 patients who underwent ERCP. Patients were randomized to receive parenteral diclofenac at a loading dose of 75 mg followed by the infusion of 5-10 mL/kg per hour isotonic saline over 4 h after the procedure, or the infusion of 500 mL isotonic saline as placebo. Patients were evaluated clinically, and serum amylase levels were measured 4, 8 and 24 h after the procedure.RESULTS: The two groups were matched for age, sex, underlying disease, ERCP findings, and type of treatment. The overall incidence of pancreatitis was 7.5% in the diclofenac group and 17.5% in the placebo group (12.5% in total). There were no significant differences in the incidence of pancreatitis and other variables between the two groups. In the subgroup analysis, the frequency of pancreatitis in the patients without sphincter of Oddi dysfunction (SOD) was significantly lower in the diclofenac group than in the control group (P=0.047).CONCLUSION: Intramuscular diclofenac and fluid replacement lowered the rate of pancreatitis in patients without SOD. | Altug Senol Ulku Saritas Halil Demirkan | 2009 | World Journal of Gastroenterology2009，15，32： | 20 |
| 2 | Precut sphincterotomy:A reliable salvage for difficult biliary cannulation显示文摘Even experienced endoscopists have 90% success in achieving deep biliary cannulation with standard methods. Biliary cannulation may become difficult in 10%-15% of patients with biliary obstruction and pre- cut (access) sphincterotomy is frequently chosen as a rescue treatment in these cases. Generally, precut sphincterotomy ensures a rate of 90%-100% success- ful deep biliary cannulation. The precut technique has been performed as either a fistulotomy with a needle knife sphincterotome or as a transpapillary septotomy with a standard sphincterotome. Both methods have similar efficacy and complication rates when adminis- tered to the proper patient. Although precut sphincter- otomy ensures over 90% success of biliary cannula- tion, it has been characterized as an independent risk factor for pancreatitis. The complications of the precut technique are not limited to pancreatitis. Two more important ones, bleeding and perforation, are also re- ported in some publications as being observed more commonly than during standard sphincterotomy. It is also reported that precut sphincterotomy increases morbidity when performed in patients without dilata- tion of their biliary tract. Nevertheless, precut sphinc- terotomy is a good alternative as a rescue method in the setting of a failed standard cannulation method. This paper discusses the technical details, timing, ef- ficacy and potential complications of precut sphincter- otomy. | Ulku Saritas Yucel Ustundag Ferda Harmandar | 2013 | World Journal of Gastroenterology2013，19，1： | 13 |
| 3 | Multicomponent One-pot Diastereoselective Synthesis of Biologically Important Scaffold under Microwaves显示文摘生物学上重要的 spiro 支架 4 的简单、快的三部件的 diastereoselective 合成在合理纯净从容易地可得到的 1H-indole-2,3-dione 开始被执行 1,乙醇 cyanoacetate 2 并且 3 在在高度的微波下面产出的 4-hydroxycoumarin (88%92%) 并且突然时间。 | DANDIA, Anshu SINGH, Ruby SARAWGI, Pritima KHATURIA, Sarita | 2006 | Chinese Journal of Chemistry2006，24，7： | 9 |
| 4 | Novel applications of statins for bone regeneration显示文摘The use of statins for bone regeneration is a promising and growing area of research. Statins, originally developed to treat high cholesterol, are inhibitors of the enzyme 3-hydroxy-3-methylglutaryl, the rate-limiting enzyme of the mevalonate pathway. Because the mevalonate pathway is responsible for the synthesis of a wide variety of important biochemical molecules, including cholesterol and other isoprenoids,the efects of statins are pleiotropic. In particular, statins can greatly afect the process of bone turnover and regeneration via efects on important cell types, including mesenchymal stem cells, osteoblasts, endothelial cells, and osteoclasts. Statins have also been shown to have anti-inlammatory and antimicrobial properties that may be useful since infection can derail normal bone healing. his review will explore the pleiotropic efects of statins, discuss the current use of statins for bone regeneration, particularly with regard to biomaterials-based controlled delivery, and ofer perspectives on the challenges and future directions of this emerging area of bone tissue engineering. | Sarita R.Shah Caroline A.Werlang F.Kurtis Kasper Antonios G.Mikos | 2015 | National Science Review2015，2，1： | 7 |
| 5 | The relationship between ischemic stroke and weather conditions in Duzce, Turkey显示文摘BACKGROUND: Weather conditions are thought to increase the risk of stroke occurrence. But their mechanism has not yet been clarified. We investigated possible relationships between ischemic stroke and weather conditions including atmospheric pressure, temperature, relative humidity, and wind speed.METHODS: One hundred and twenty-eight patients with ischemic stroke who had been admitted to our hospital between January 1 and December 31, 2010 were enrolled in this study. We investigated the relationship between daily cases and weather conditions the same day or 1, 2, and 3 days before stroke.RESULTS: A negative correlation was found between maximum wind speed and daily cases 3 days before stroke. As the relationship between daily cases and changes of weather conditions in consecutive days was evaluated, a negative correlation was found between daily cases and change of atmospheric pressure in the last 24 hours.CONCLUSIONS: The maximum wind speed 3 days before stroke and change of atmospheric pressure in the last 24 hours were found to increase the cases of ischemic stroke. We recommend that individuals at risk of ischemic stroke should pay more attention to preventive measures, especially on days with low maximum wind speed, on subsequent 3 days, and on days with low atmospheric pressure in the last 24 hours. | Harun Gunes Hayati Kandis Ayhan Saritas Suber Dikici Ramazan Buyukkaya | 2015 | World Journal of Emergency Medicine2015，6，3： | 6 |
| 6 | Bioefficacy of Mentha piperita essential oil against dengue fever mosquito Aedes aegypti L显示文摘Objective:To assess the larvicidal and repellent potential of the essential oil extracted from the leaves of peppermint plant,Mentha piperita(M.piperita)against the larval and adult stages of Aedes aegypli(Ae.Aegypti).Methods:The larvicidal potential of peppermint oil was evaluated against early fourth instar larvae of Ae.aegypli using WHO protocol.The mortality counts were made after 24 and 48 h,and LC_(50)and LC_(90)values were calculated.The efficacy of peppermint oil as mosquito repellent was assessed using the human-bait technique.The measured area of one arm of a human volunteer was applied with the oil and the other arm was applied with ethanol.The mosquito bites on both the arms were recorded for 3 rain after every 15 min.The experiment continued for 3 h and the percent protection was calculated.Results:The essential oil extracted from M.piperita possessed excellent larvicidal efficiency against dengue vector.The bioassays showed an LC_(50)and LC_(90)value of 111.9 and 295.18 ppm,respectively after 24 h of exposure.The toxicity of the oil increased 11.8%when the larvae were exposed to the oil for 48h.The remarkable repellent properties of M.piperita essential oil were established against adults Ae.aegypti.The application of oil resulted in 100%protection till 150 min.After next 30 min,only 1-2 bites were recorded as compared with 8-9 bites on the control arm.Conclusions:The peppermint essential oil is proved to be efficient larvicide and repellent against dengue vector.Further studies are needed to identify the possible role of oil as adulticide.oviposition deterrent and ovicidal agent.The isolation of active ingredient from the oil could help in formulating strategies for mosquito control. | Sarita Kumar Naim Wahab Radhika Warikoo | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，2： | 5 |
| 7 | Perspectives on the prevention and treatment of infection for orthopedic tissue engineering applications显示文摘The emergence of orthopedic tissue engineering devices as viable clinical solutions demands that the field address significant clinical complications associated with the implantation of foreign materials in the body,especially infection.While tissue engineering has focused on the development of methods to regenerate and repair,until recently there has been a relative dearth of literature regarding the intersection of tissue engineering and infection.In particular,local delivery of antimicrobials has long been of clinical interest,but only recently has that been translated into the realm of tissue engineering.In this perspective,we briefly review major modes of local delivery for infection prevention and treatment and discuss possible strategies for preventing implant-associated infections. | SHAH Sarita R KASPER F Kurtis MIKOS Antonios G | 2013 | Chinese Science Bulletin2013，58，35： | 4 |
| 8 | Rilotumumab in combination with epirubicin, cisplatin, and capecitabine as first-line treatment for gastric or oesophagogastric junction adenocarcinoma: an open-label, dose de-escalation phase 1b study and a double-blind, randomised phase 2 study显示文摘 | Timothy Iveson Ross C Donehower Irina Davidenko Sergey Tjulandin Andrzej Deptala Mark Harrison Somanath Nirni Kuntegowdanahalli Lakshmaiah Anne Thomas Yizhou Jiang Min Zhu Rui Tang Abraham Anderson Sarita Dubey Kelly S Oliner Elwyn Loh | 2014 | Lancet Oncology2014，，9： | 3 |
| 9 | Differences in parents of pediatric liver transplantation and chronic liver disease patients显示文摘BACKGROUND With advancements in the treatment of chronic liver disease(CLD),including liver transplantation(LT),quality of life and satisfaction after LT have become an important issue for pediatric patients and their parents.More evidence-based information is needed to describe and assess the impact of pediatric CLD on parents and the satisfaction of parents with treatment to better understand their needs.AIM To assess the satisfaction of parents of pediatric LT patients and that of parents of pediatric CLD patients METHODS During this survey,data were collected from parents of pediatric patients who underwent LT between January 2010 and April 2017(LT group;n=91)and parents of pediatric patients with chronic liver disease(CLD group;n=94).Group comparisons were made based on the pediatric health-related quality of life(PedsQL)health care parent satisfaction scale,impact on family scale(IFS)and demographic characteristics.The PedsQL was administered to parents during a phone interview and the results were used to assess the health carerelated satisfaction of parents.The IFS was used to assess the impact of the child’s CLD status on the family.Demographic variables such as education level(elementary vs middle vs high vs university),monthly income(low vs middle vs high),and place of residence(village vs town vs city)were compared between CLD and LT parent groups.Finally,PedsQL and IFS results were also analyzed according to demographic variables.RESULTS A total of 185 parents aged 19 to 65 years were included.There were statistically significant differences between the LT and CLD groups in terms of career(P<0.001),monthly income(P=0.016),and education level(P=0.041).According to the PedsQL results,family inclusion,communication,technical skills,emotional needs,and overall satisfaction were significantly different between the groups;the LT group had consistently higher scores(P<0.001).Additionally,scores for the IFS parameters of financial impact,familial-social impact,personal strain,and total impact were consistently higher for the LT group(P<0.001).There were statistically significant relationships between education level,monthly income,and place of residence according to the IFS results but not the PedsQL results.There were inverse relationships between the difficulties that parents experience because of their child’s health and education levels,monthly income,and place of residence.However,no relationship was found between education level,monthly income,or place of residence and satisfaction with health care services provided in the hospital according to the PedsQL results.CONCLUSION Parents of children who underwent LT were very satisfied with the health care services provided to their children.However,they had more difficulties than parents of children with CLD. | Sami Akbulut Gulsen Gunes Hasan Saritas Bahar Aslan Yunus Karipkiz Khaled Demyati Sukru Gungor Sezai Yilmaz | 2020 | World Journal of Clinical Cases2020，8，11： | 3 |
| 10 | Acute intoxication cases admitted to the emergency department of a university hospital显示文摘BACKGROUND: This study aimed to describe the clinical and socio-demographic aspects of acute poisoning in 2010 in Duzce City, Northwest Anatolian Region of Turkey.METHODS: Acute poisoning was due to the intentional ingestion of drugs in young and adult people(≥16), who were treated at the Emergency Service of Duzce University Medical Hospital, Turkey from January 1, 2010 to December 31, 2010. In this retrospective and descriptive study, 95 patients were diagnosed with intoxications and 30 of them intentionally ingested drugs to commit suicide. Records of the patients diagnosed with intoxication were obtained from the Clinical Archive of the hospital. Their diagnoses were established according to the International Statistical Classification of Diseases and Related Health Problems. Codes X60-X84 of this classification were used to classify self-infringed drug injuries and drug poisoning.RESULTS: In this series, 35(36.8%) patients were male and 60 patients(63.2%) female. The male/female ratio was 1.0/1.7. The mean age of the patients was 33.1±14.2 years; 17(17.9%) patients were below 20 years old and 9(9.5%) were older than 50 years. Of these patients, 29(30.5%) were single, 7(7.4%) divorced or separated, and 59(62.1%) married. Their mean time for admission to the emergency service after the incident was 208±180(15–660) minutes. The mean time for admission to the emergency service for patients with food intoxication after the incident was 142±160 minutes, for those with drug intoxication 173±161 minutes, for those with carbon monoxide(CO) intoxication 315±209 minutes, and for those with undefined intoxication 289±166 minutes(P=0.005). Most of the intoxication cases occurred in winter(41.1%, 39 of 95 patients). Admissions to the emergency service were most common in December and April(21 and 16 of 95 patients, respectively). Sixty-five(68.4%) cases were involved in non-deliberate poisoning, whereas 30(31.6%) were involved in deliberate poisoning. Twenty-six of the 95 patients with acute poisonings had mortality risk at admission, however only one died from CO intoxication in the emergency service(1.1%). Suicide attempts were more common in females than in males(21 of 30 patients, 70%, P<0.05). CONCLUSION: In Duzce City of Turkey, most intoxication cases occurred in winter, especially in December. They had non-deliberate poisoning, but deliberate poisoning in suicide attempts was more common in females than in males. | Ertugrul Kaya Aylin Yilmaz Ayhan Saritas Serdar Colakoglu Davut Baltaci Hayati Kandis Ismail Hamdi Kara | 2015 | World Journal of Emergency Medicine2015，6，1： | 3 |
| 11 | Larvicidal and irritant activities of hexane leaf extracts of Citrus sinensis against dengue vector Aedes aegypti L.显示文摘Objective:To assess the larvicidal and irritant activities of the hexane extracts of leaves of Citrus sinensis(C.sinensis)against the early fourth instars and female adults of Aedes aegypti(Ae.aegypti).Methods:The larvicidal potential of the prepared leaf extract was evaluated against early fourth instar larvae of Ae.aegypli using WHO protocol.The mortality counts were made after 24 h and LC_(50)and LG_(50)values were calculated.The efficacy of extract as mosquito irritant was assessed by contact irritancy assays.Extract-impregnated paper was placed on a glass plate over which a perspex funnel with a hole on the top was kept inverted.Single female adult,3-day old unfed/blood-fed,was released inside the funnel.After 3 min of acclimatization time,the time taken for the first take-off and total number of flights undertaken during 15 min were scored.Results:The citrus leaf extracts from hexane possessed moderate larvicidal efficiency against dengue vector.The bioassays resulted in an LC_(50)and LC_(90)value of 446.84 and 1370.96 ppm,respectively after 24 h of exposure.However,the extracts were proved to be remarkable irritant against adults Ae.aegypti,more pronounced effects being observed on blood-fed females than unfed females.The extract-impregnated paper was thus proved to be 7-11 times more irritable as compared with the control paper.Conclusions:The hexane extracts from C.sinensis leaves are proved to be reasonably larvicidal But remarkably irritant against dengue vector.Further studies are needed to identify the possible role of extract as adulticide,oviposition deterrent and ovicidal agent.The isolation of active ingredient from the extract could help in formulating strategies for mosquito control. | Radhika Warikoo Ankita Ray Jasdeep Kaur Sandhu Roopa Sanial Naim Wahab Sarita Kumar | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，2： | 2 |
| 12 | Factors affecting anxiety, depression, and self-care ability in patients who have undergone liver transplantation显示文摘BACKGROUND Depression,anxiety,and altered self-care ability are among the most important factors affecting the quality of life of liver transplant recipients.Depending on the severity of the underlying liver disease,signs and symptoms of anxiety and depression may become more pronounced.AIM To evaluate the factors affecting depression,anxiety and self-care abilities of liver transplant recipients.METHODS Recipients who are≥18 years and who underwent liver transplantation at Inonu University Liver Transplantation Institute were included in this descriptive and cross-sectional study.Sample size analysis showed that the minimum number of recipients should be 301(confidence level=95%,confidence interval=2.5,population=1382).Three hundred and twenty recipients were interviewed and 316 recipients that have answered the questionnaires accurately were analyzed.The dependent variables were the Beck Depression Scale,State-Trait Anxiety Scale(Form I and II),and Self-Care Agency Scale.The independent variables of the study were sociodemographic characteristics,biliary complications,hepatocellular carcinoma,recommending liver transplantation to other patients,and the interval of out-patient clinic visits.RESULTS Self-care ability scores were lower(P=0.002)and anxiety scores were higher(P=0.004)in recipients with biliary complications.On the other hand,in recipients with hepatocellular carcinoma,self-care scores were lower(P=0.006)while depression(P=0.003)and anxiety scores(P=0.009)were higher.Liver transplantation recipients with a monthly income<3000 Turkish liras had higher depression(P<0.001)and anxiety(P=0.003)scores.The recipients who stated that they would not recommend liver transplantation to others had lower self-care scores(P=0.002),higher depression(P<0.001),higher state anxiety(P=0.02),and trait anxiety(P<0.001)scores.CONCLUSION Presence of biliary complications and hepatocellular carcinoma,low income level,and an obligation for monthly visits to the outpatient clinic are factors that are found to affect self-care capability,depression,and anxiety. | Sami Akbulut Ali Ozer Hasan Saritas Sezai Yilmaz | 2021 | World Journal of Gastroenterology2021，27，40： | 2 |
| 13 | 含有0.8%精氨酸、PVM/MA共聚物、焦磷酸盐和0.05%氟化钠的新型脱敏漱口水的作用方式的研究显示文摘目的:经提出并证实,采用Pro-Argin TM漱口水工艺制成的含有0.8%精氨酸、PVM/MA共聚物、焦磷酸盐和0.05%氟化钠的精氨酸漱口水的作用方式,可利用多种体外技术产生封闭作用。方法:采用定量和定性实验室技术研究这种新型精氨酸漱口水的作用方式。利用共焦激光扫描显微镜检查(CSLM)和原子力显微镜检查(AFM)研究牙本质表面的水合层。化学分析电子光谱学(ESCA)、二次离子质谱学(SIMS)和近红外光谱学(NIR)提供了关于这种漱口水的化学性质的信息。结果:使用精氨酸漱口水后,采用CLSM观察暴露牙本质小管上的水合层的形成。经荧光研究证实,水合层可渗透到牙本质小管内壁。经AFM研究证实,精氨酸漱口水对牙本质表面具有亲合力,这与其粘合性质相一致。NIR表明,使用漱口水数次后,精氨酸会沉积下来,而ESCA/SIMS检测到磷酸基团和有机酸基团的存在,表明PVM/MA共聚物和焦磷酸盐是连同精氨酸一起沉积下来的。结论:研究表明:富含精氨酸层连同来自于含有0.8%精氨酸、PVM/MA共聚物、焦磷酸盐和0.05%氟化钠的无酒精漱口水的共聚物和磷酸盐离子一起沉积下来后,可封闭牙本质表面。 | Sarita V.Melloa Evangelia Arvanitidoua Michael A.Stranicka Ramon Santanaa Yasemin Kutesb Bryan Hueyb | 2014 | 口腔护理用品工业2014，24，6： | 2 |
| 14 | 市售长叶松油和锡兰肉桂油对登革热媒蚊埃及伊蚊的灭幼效果(英文)显示文摘松油和桂皮油由于具有芳香性气味,因而成为良好的成虫驱避剂,但是关于它们对蚊虫的杀幼虫作用研究不多。为揭示市售的长叶松Pinus longifolia油和锡兰肉桂Cinnamomum zeylanicum油对来源于印度德里的埃及伊蚊Aedes aegypti4龄幼虫的毒杀潜力,我们进行了室内研究,以幼虫死亡率及行为改变和形态改变等指标评估其杀幼虫潜力。结果表明:两种油对埃及伊蚊4龄幼虫均具有毒杀作用,且松油的灭幼效果优于桂皮油。松油的LC50和LC70值分别为0.33093mg/L和0.54476mg/L,而桂皮油的LC50和LC70值分别为0.63159mg/L和0.77736。进一步观察发现,LC90剂量下桂皮油的杀幼虫潜力强于松油,其LC90为1.11879mg/L,而松油的LC90为1.04915mg/L。在处理的幼虫中观察到行为改变,如兴奋、坐立不安、颤抖、痉挛然后瘫痪,说明这两种油可能对其神经肌肉系统产生了影响。显微观察处理幼虫的形态改变发现,与对照相比,大多数器官的外观正常,只是肛鳃略为内收缩而引起结构畸形,提示肛腮可能是这两种油的作用位点,腮的功能异常引起了幼虫死亡。这两种油品可开发用作防治蚊虫的新型杀幼虫药剂。 | Radhika WARIKOO Naim WAHAB Sarita KUMAR | 2011 | 昆虫学报2011，54，7： | 2 |
| 15 | Attitudes,awareness,and knowledge levels of the Turkish adult population toward organ donation:Study of a nationwide survey显示文摘BACKGROUND The most important factors affecting attitudes on organ donation are socioeconomic, educational, cultural, and religious factors in many countries.AIM To evaluate the attitudes, awareness, and knowledge levels of the Turkish adult population toward organ donation.METHODS This nationwide study surveyed 3000 adults(≥ 18 years) in Turkey. To ensure a representative sample, the Nomenclature of Territorial Units for Statistics-Ⅱ(modified for Turkey) was used. Turkey was divided into 26 regions based on social, economic, and geographic criteria as identified by the Turkish Statistical Institute. A stratified sampling method was used with an even distribution of adults across cities and towns based on population data. Data were collected by the PRP Research and Consultancy Company using computer-assisted personal interviews.RESULTS Out of 3000 individuals represented in the study population, 1465(48.8%) were male and 1535(51.2%) female. The results showed that most participants were under 45 years(59.0%) and married(72.1%), some had a bachelor’s degree or higher(21.9%), and very few(1.5%) had any direct experience with organ transplantation-whether in the family, or a family member on a transplantation waiting list. Most of the study population(88.3%) had not considered donating an organ, however, most(87.9%) said that they would accept an organ from a donor if they needed one. Among the individuals surveyed, 67% were willing to donate an organ to a close relative, while 26.8% would donate an organ to an unrelated person. Only 47.2% said they had adequate information about brain death, and 85.2% refused to consent to donating organs of family members declared brain dead. Only 33.9% thought they had adequate information about organ donation. The main source of information was the television. The two main reasons for refusing organ donation were that it was too soon to think about organ donation and the importance of retaining the integrity of the dead person’s body.CONCLUSION This study showed that Turkey’s adult population has inadequate knowledge about organ donation. The study advocates for public education programs to increase awareness among the general population about legislation related to organ donation. | Sami Akbulut Ali Ozer Ayse Gokce Khaled Demyati Hasan Saritas Sezai Yilmaz | 2020 | World Journal of Clinical Cases2020，8，11： | 2 |
| 16 | 土耳其粉末冶金发展现状显示文摘土耳其是一个正在实现工业化的发展中国家 ,其粉末冶金工业始创于2 0世纪 70年代。目前 ,土耳其粉末冶金的发展几乎涉及到该行业所有的应用领域 ,但主要依赖于汽车工业和石材加工工业 ,平均每辆轿车上的粉末冶金零件用量为 7kg ,汽车年产量约 1 2 0万辆。 1 988年石材产量达 2 1 0万t,继意大利、中国和西班牙之后居世界第 4位。 1 998年土耳其的粉末冶金产值达到 1亿 5千万美元。 | Suleyman SARITAS Mehmet Turker 常新春 | 2002 | 粉末冶金工业2002，12，3： | 2 |
| 17 | Putrescine alleviation of growth in salt stressed Brassica juncea by inducing antioxidative defense system显示文摘 | Sarita Verma Shyam Narayan Mishra | 2005 | Journal of Plant Physiology2005，，6： | 2 |
| 18 | Reduced field-of-view dif- fusion imaging of the human spinal cord : comparison with conven- tional single-shot echo-planar imaging 显示文摘 | Zaharchuk G Saritas EU Andre JB | 2011 | AJNR2011，32，： | 1 |
| 19 | Transthoracic echoeardiogphic guidance during transcatheter closure of atrial septal defects in children and adults 显示文摘 | Erdern A Saritas T Zeybek C | 2013 | Int J Cardiovasc Imaging2013，29，1： | 1 |
| 20 | Trace elements in the scalp hair of patients with alcohol induced psyehosis显示文摘 | Pradeep AS Nagaraju GJ Sarita P | 2012 | J Radio- anal Nucl Chem2012，294，2： | 1 |
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