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| 1 | Isolation of the mucilages from Hibiscus rosasinensis linn.and Okra(Abelmoschus esculentus linn.) and studies of the binding effects of the mucilages显示文摘Objective:To isolate and evaluate comparatively the binding efficacy of the mucilages obtained from the plants of Hibiscus rosasinensis and Okra(Abelmoschus esculentus).Methods:Extraction of mucilages from the leaves of Hibiscus and pods of Okra(Ladies finger) was carried out by a cold maceration process.The extracted mucilages were subjected to various physicochemical properties for its suitability as an excipient in the formulation of tablet dosage form.Different concentrations(10,8,5,2 and 1%w/v) of binder solutions of Hibiscus and Okra were used for the formulation of tablets and the formulated tablets were evaluated by studying the standard parameters like diameter,thickness,weight variation,hardness,friability,disintegration and in vitro dissolution.Stability studies of the formulated tablets were conducted for four weeks. Results:The formulated tablets prepared using the mucilages of both Hibiscus and Okra had good appearance.The in vitro drug release profile of the tablets prepared using Okra mucilage had an optimum of 90%at a mucilage concentration of 1%w/v concentration mucilage itself within 4 h.Conclusions:According to the observations,the lower concentration levels of Okra can be used as an alternative binder to starch.The higher concentration levels of Okra mucilage show a slow and sustained release,and can be considered as an alternative natural excipient in the modified drug delivery systems.At the same time,the above natural excipient of Hibiscus mucilage could be used as a platform for prolonged release if its binder concentrations are increased. | Ameena K Dilip C Saraswathi R Krishnan PN Sankar C Simi SP | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，7： | 8 |
| 2 | A gene for hereditary pancreatitis maps to chromosome 7q35显示文摘 | DC Whitcomb RA Preston CE Aston MJ Sossenheimer PS Barua Y Zhang A Wong- Chong GJ White PG Wood LK Gates C Ulrich SP Martin JC Post GD Ehrlich | 1996 | Gastroenterology1996，，6： | 2 |
| 3 | B- type natriuretic peptide limits infarct size in rat isolated hearts via KATP channel opening 显示文摘 | D'Souza SP Yellon DM Martin C | 2003 | Am J Physiol Heart Circ Physiol2003，284，5： | 1 |
| 4 | Lost in Translation: Ob- stacles to Translational Medicine 显示文摘 | Mankoff SP Brander C Fetxone S | 2004 | J Transl Med2004，2，1： | 1 |
| 5 | Living, autologous pulmonary artery conduits tissue engineered from human umbilical cord cells显示文摘 | Hoerstrup SP Kadner A Breymann C | 2002 | Ann Thorac Surg2002，74，1： | 1 |
| 6 | Independent validation of the 2010 American Joint Committee on Cancer TNM classification for renal cell carcinoma: results from a large, single institution co- hort 显示文摘 | Kim SP Alt AL Weight C J | 2011 | J Urol2011，185，： | 1 |
| 7 | Exhaled nitric oxide reflects asthma severity and asthma control 显示文摘 | Delgado-Coreoran C Kissoon N Murphy SP | 2004 | Pediatr Crit Care Med2004，5，1： | 1 |
| 8 | A prospective evaluation of anterior transposition of the inferior oblique muscle,with and without resection,in the treatment of dissociated vertical deviation显示文摘 | Quinn AG Kraft SP Day C | 2000 | J AAPOS2000，4，6： | 1 |
| 9 | Estrogen increases mitoehondrial efficiency and reduces oxidative stress in cerebral blood vessels显示文摘 | Stirone C Duckles SP Krause DN | 2005 | Mol Pharmacol2005，68，4： | 1 |
| 10 | A retrospective study of combined fixed-removable reconstruction with their analysis of failures显示文摘 | Studer SP Mader C Stahel W | 1998 | J Oral Rehabil1998，25，： | 1 |
| 11 | Proteomic analysis of Arabidopsis seed germination and priming显示文摘 | Gallardo K Job C Groot SP | 2001 | Plant Physiology2001，126，： | 1 |
| 12 | Rapid prenatal diagnosis of aneuploidy using quantitative fluorescence PCR (QF-PCR)显示文摘 | Ogilvie CM Donaghue C Fox SP | 2005 | J Histochem Cytochem2005，53，3： | 1 |
| 13 | Evaluation and treat- ment of Chagas disease in the United States: a systematic review 显示文摘 | Bern C Montgomery SP Herwaldt BL | 2007 | JAMA2007，298，18： | 1 |
| 14 | The diagnostic accuracy of 256-row computer t omography angiography compared with invasive coronary angiography in patients with suspected coronary artery disease 显示文摘 | Chao SP Law WY Kuo C J | 2010 | Eur Heater J2010，31，15： | 1 |
| 15 | Epidural Ster- oids, Etanercept, or Saline in Subacute Sciatica: A Mul- ticenter, Randomized Trial显示文摘 | Cohen SP White RL Kurihara C | 2012 | Ann Intern Med2012，156，8： | 1 |
| 16 | Immune recovery uveitis and uveitis in AIDS: Clinical predictors, sequelae and treatment outcome 显示文摘 | Karavellas MP Azen SP Macdonald C | 2001 | Retina2001，21，： | 1 |
| 17 | Intention-to-treat analysis of pulmonary artery banding in conditions with a morphological right ventricle in the systemic circulation with a view to anatomic biventric- ular repair显示文摘 | Winlaw DS McGuirk SP Balmer C | 2005 | Circulation2005，111，4： | 1 |
| 18 | A prospective evaluation of anterior transposition of the inferior oblique musele,with and without resection,in the treatment of dissociated vertical deviation显示文摘 | Quinn AG Kraft SP Day C | 2000 | J AAPOS2000，4，6： | 1 |
| 19 | Strategies for the rapid prenatal diagnosis of chromosome aneuploidy 显示文摘 | Mann K Donaghue C Fox SP | 2004 | Eur J Hum Genet2004，12，： | 1 |
| 20 | Tumor-associated macrophages and survival in classic Hodgkin's lymphoma显示文摘 | Steidl C Lee T Shah SP | 2010 | N Engl J Med2010，362，： | 1 |
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