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94篇 您的检索式:作者名="Schierling"
    题名 作者 年代 出处 被引量
1Observation of an α-synuclein liquid droplet state and its maturation into Lewy body-like assemblies显示文摘Misfoldedα-synudein is a major component of Lewy bodies,which are a hallmark of Parkinson's disease(PD).A large body of evidence shows thatα-synuclein can aggregate into amyloid fibrils,but the relationship between a-synuclein self-assembly and Lewy body formation remains unclear.Here,we show,both in vitro and in a Caenorhabditis elegans model of PD,thatα-synuclein undergoes liquid-liquid phase separation by forming a liquid droplet state,which converts into an amyloid-rich hydrogel with Lewy-body-like properties.This maturation process towards the amyloid state is delayed in the presence of model synaptic vesicles in vitro.Taken together,these results suggest that the formation of Lewy bodies may be linked to the arrested maturation ofα-synuclein condensates in the presence of lipids and other cellular components.Maarten C.Hardenberg Tessa Sinnige Sam Casford Samuel T.Dada Chetan Poudel Elizabeth A.Robinson Monika Fuxreiter Clemens F.Kaminksi Gabriele S.Kaminski Schierle Ellen A.A.Nollen Christopher M.Dobson Michele Vendruscolo 2021Journal of Molecular Cell Biology2021,13,4:3
2Determinants of endotoxin levels in living environments of farmers' children and their peers from rural areas显示文摘Waser M Schierl R von Mutius E 2004Clin Exp Allergy2004,34,:1
3Human cytomegalovirustegument protein ppUL35 is important for viral replication andparticle formation 显示文摘Schierling K Buser C Mertens T 2005J Virol2005,79,5:1
4The CMT-process-a revolution in welding technology显示文摘SCHIERL A 2005Welding in the World2005,49,9:1
5Human cytomegalovirus tegument proteins ppUL82 (pp71) and ppUL35 interact and cooperatively activate the major immediate-early enhancer显示文摘Schierling K Stamminger T Mertens T 2004J Virol2004,78,17:1
6Oxygen overvoltage at insoluble anodes in the system Pb-Ag-Ca (German) 显示文摘HEIN K SCHIERLE T 1992Erzmetall1992,44,:1
7Chemical vapor deposition of smooth α-Al203 films on nickel base superalloy as diffusion harriers 显示文摘MULLER J SCHIERLING M ZIMMERMANN E 1999Surface and Coatings Technology1999,12,:1
8Content and Isometic ratio lycopene in food and human blood plasma显示文摘Joseph Schierle 1997Food Technology1997,59,3:1
9Study on the Prevention of Allergy in Children in Europe (SPACE):Allergic sensitization at 1 year of age in a controlled trial of allergen avoidance from birth显示文摘 Gartner C Schierl M 2003Pediatr Allergy Immunol2003,14,:1
10Staphylococcial hiofilms impair wound healing by delaying reepithelialization in amurine cutaneous wound model显示文摘Schierle CF De la Garza M Mustoe TA 2009Wound Repair Iiegen2009,17,3:1
11Impact of singular exces- sive computer game and television exposure on sleep patterns and memory performance of school - aged children 显示文摘Dworak M Schierl T Bruns T 2007Pediatrics2007,120,5:1
12Transport and signaling of SVC in IP networks显示文摘Wenger S Wang Ye-Kui Schierl T 2007IEEE Transactions on circuits and systems for video technology2007,17,9:1
13Staphylococcal bio- films impair wound healing by delaying reepithelization in a murine cutaneous wound model 显示文摘Schierle CF Dela Garza M Mustoe TA 2009Wound Rep Regen2009,17,3:1
14Improving the survival of grafted dopaminer gic neuronsa review over current approaches显示文摘Brundin P Karlsson J Emgfird M Schierle G S Hansson O Petersn A 2000Cell Trans plant2000,9,:1
15Increased intravascular flow rate triggers cerebral arteriogenesis 显示文摘Schierling W Troidl K Mueller C 2009Cereb Blood Flow Metab2009,29,4:1
16Improving outcomes of the distally based hemisoleus flap: principles of angiosomes in flap design 显示文摘Schierle CF Rawlani V Galiano RD 2009Plast Reconstr Surg2009,123,6:1
17Experimental application of a biomaterial in bifocal transport osteogenesis for craniofacial reconstruction显示文摘Franz-Josef Kramer Branko Sinikovic Michal Mueller Meike Rahmstorf Hannes Schierle 2008Journal of Cranio-Maxillofacial Surgery2008,,4:1
18PGC-la and PGC-II3 have both similar and distinct effects on myofiber switching toward an oxidative phenotype显示文摘Mortensen O H Frandsen L Schierling P 2006Am J Physiol Endo- crinol Metab2006,291,4:1
19Staphylococcal biofilms impair wound healing by delaying reepithelization in a murine cutane- ous wound modd显示文摘Schierle CF Dela Garza M Mustoe TA 2009Wound Rep Regen2009,17,3:1
20Ortho- and heterotopic bone grafts in bifocal transport osteogenesis for craniofacial reconstruction—an experimental study in sheep显示文摘F.-J. Kramer M. Mueller M. Rahmstorf G.R.J. Swennen R. Dempf H. Schierle 2004International Journal of Oral & Maxillofacial Surgery2004,,6:1
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