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| 1 | Impact of body composition on survival and morbidity after liver resection in hepatocellular carcinoma patients显示文摘Background: Hepatocellular carcinoma is the most common innate liver tumor. Due to improved surgical techniques, even extended resections are feasible, and more patients can be treated with curative intent. As the liver is the central metabolic organ, preoperative metabolic assessment is crucial for risk stratification. Sarcopenia, obesity and sarcopenic obesity characterize body composition and metabolic status. Here we present the impact of body composition on survival after liver resection in patients with hepatocellular carcinoma. Methods: A retrospective database analysis of 70 patients who were assigned for liver resection due to hepatocellular carcinoma was conducted. For assessment of sarcopenia and obesity, skeletal muscle surface area was measured at lumbar vertebra 3 level(L3) in preoperative four-phase contrast enhanced abdominal CT scans, and L3 muscle index and body fat percentage were calculated. Results: Univariate analysis comparing the survival curves using the score test demonstrated superior postoperative overall survival for sarcopenic( P = 0.035) and sarcopenic obese( P = 0.048) patients as well as a trend favoring obese( P = 0.130) subjects. Whereas multivariate analysis could not identify significant difference in postoperative survival regarding sarcopenia, obesity or sarcopenic obesity. Only large tumor size, multifocal disease and male gender were risk factors for long-term survival. Conclusions: Sarcopenia, obesity and sarcopenic obesity are indeed no risk factors for poor postoperative survival in this study. Our data do not support the evaluation of sarcopenia, obesity and sarcopenic obesity before liver resection in hepatocellular carcinoma patients. | Andreas Kroh Diane Uschner Toine Lodewick Roman M Eickhoff Wenzel Sch?ning Florian T Ulmer Ulf P Neumann Marcel Binneb?sel | 2019 | Hepatobiliary & Pancreatic Diseases International2019，18，1： | 5 |
| 2 | 肠道菌群促进血管紧张素Ⅱ诱导的高血压和血管功能障碍显示文摘肠道微生物对宿主生理反应及对免疫功能的发展来说必不可少。肠道菌群对血压和全身血管功能等这些由免疫细胞功能决定的生理过程的影响知之甚少。方法:与常规饲养的小鼠(conventionally raised rats,CONV-R)比较,未受任何细菌影响的无菌小鼠(GF)表现出较为严重的全身性辅助性T细胞1型滞后。 | 刘莉 叶鹏 Karbach SH Schnfelder T Brandao I Wilms E Hrmann N Jckel S Schüler R Finger S Knorr M Lagrange J Brandt M Waisman A Kossmann S Schüfer K Münzel T Reinhardt C Wenzel P | 2016 | 中华高血压杂志2016，24，10： | 5 |
| 3 | Seed dormancy in Carex canescens, regional differences and ecological consequences显示文摘 | Sch T W Milberg P | 1997 | Oikos1997，78，： | 1 |
| 4 | Validierung einer deutsehsprachigen Version des Body Image Avoidance Questionnaire BIAQ显示文摘 | LEGENBAUER T VOCKS S SCH?TT-STR?MEL S | | Diagnostiea0，20，53： | 1 |
| 5 | Loss-ofFunction mutations in the filaggrin gene and allergic contact sensitization to nickel显示文摘 | Novak N Baurecht H Schfer T | 2008 | J Invest Dermatol2008，128，： | 1 |
| 6 | Biological background and role of adiponectin as marker for insulin resistance and cardiovascular risk显示文摘 | Schndorf T Maiworm A Emmison N | 2005 | Clin Lab2005，51，910： | 1 |
| 7 | Intravenous brainderived neurotrophic factor enhances poststroke sensorimotor recovery and stimulates neurogenesis显示文摘 | Sch bitz WR Steigleder T Cooper-Kuhn CM | 2007 | Stroke2007，38，： | 1 |
| 8 | The optimal carrier for BMP-2 a comparison of collagen versus fibrin ma-trix显示文摘 | Schützenberger S Schultz A Hausner T | 2012 | Arch Orthop Trauma Surg2012，132，9： | 1 |
| 9 | 查看详情显示文摘 | Gindl W Sch(o)berl T Jeronimidis G | | 0，，04： | 1 |
| 10 | Cloning,sequencing,and characterization of a heat-and alkali-stable type Ⅰ pullulanase from Anaerobranca gottschalkii显示文摘 | Bertoldo C Armbrecht M Becker F Sch(a)fer T Antranikian G Liebl W | | 0，，06： | 1 |
| 11 | Marginalized particle filters for mixed linear/nonlinear state-space models显示文摘 | SCH?N T GUSTAFSSON F NORDLUND P | 2005 | IEEE Transactions on Signal Processing2005，53，7： | 1 |
| 12 | Use of Saccharomyces cerevisiae cells immobilized on orange peel as biocatalyst for alcoholic fermentation显示文摘 | Sch B S Coleraine B T | 2007 | Bioresource Technology2007，98，4： | 1 |
| 13 | Quantum Dot in the Kondo Regime Coupled to Superconductors显示文摘 | BUITELAAR M R NUSSBAUMER T SCH O¨NENBERGER C | 2002 | Phys Rev Lett2002，89，25： | 1 |
| 14 | Variation in seed dormancy of the wetland sedge, Carex elongata, between populations and individuals in two consecutive years显示文摘 | Sch T W Rave G | 2003 | Seed Science Research2003，13，： | 1 |
| 15 | Bcl-2/Bcl-xl bispecific antisence treatment sensitizes breast cancinoma cells to doxorubicin,paclitaxel and cyclophosphamide显示文摘 | Simes-Wüst AP Schürpf T Hall J | 2002 | Breast Cancer Res Treat2002，76，2： | 1 |
| 16 | Cadmium-induced changes in antioxidant systems,hydrogen peroxide content,and differentiation in scots pine roots显示文摘 | Schützendübel A Schwanz P Teichmann T | 2001 | Plant Physiol2001，127，： | 1 |
| 17 | Towards safer reoperations:special aspects in aortic dissection显示文摘 | Schfers HJ Kunihara T | 2008 | Eur J Cardiothorac Surg2008，33，4： | 1 |
| 18 | Botox, dilation, or myotomy? Clinical outcome of interventional and surgical therapies for achalasia显示文摘 | Christian Alexander Gutschow Ulrich T?x Jessica Leers Hartmut Sch?fer Klaus Ludwig Prenzel Arnulf H. H?lscher | 2010 | Langenbeck’s Archives of Surgery2010，，8： | 1 |
| 19 | System identification of nonlinear state-space models显示文摘 | SCH(O)N T B WILLS A NINNESS B | | 0，，01： | 1 |
| 20 | Management of esophageal perforations显示文摘 | Schmidt SC Strauch S R(o)sch T | | 0，，11： | 1 |
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