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| 1 | Beneficial effects of nutritional supplements on intestinal epithelial barrier functions in experimental colitis models in vivo显示文摘Acute and chronic colitis affect a huge proportion of the population world-wide.The etiology of colitis cases can be manifold,and diet can significantly affect onset and outcome of colitis.While many forms of acute colitis are easily treatable,chronic forms of colitis such as ulcerative colitis and Crohn’s disease(summarized as inflammatory bowel diseases)are multifactorial with poorly understood pathogenesis.Inflammatory bowel diseases are characterized by exacerbated immune responses causing epithelial dysfunction and bacterial translocation.There is no cure and therapies aim at reducing inflammation and restoring intestinal barrier function.Unfortunately,most drugs can have severe side effects.Changes in diet and inclusion of nutritional supplements have been extensively studied in cell culture and animal models,and some supplements have shown promising results in clinical studies.Most of these nutritional supplements including vitamins,fatty acids and phytochemicals reduce oxidative stress and inflammation and have shown beneficial effects during experimental colitis in rodents induced by dextran sulphate sodium or 2,4,6-trinitrobenzene sulfonic acid,which remain the gold standard in pre-clinical colitis research.Here,we summarize the mechanisms through which such nutritional supplements contribute to epithelial barrier stabilization. | Hilda Vargas-Robles Karla Fabiola Castro-Ochoa Alí Francisco Citalán-Madrid Michael Schnoor | 2019 | World Journal of Gastroenterology2019，25，30： | 5 |
| 2 | Lattice basis reduction improved practical algorithms and solving subsets sum problems 显示文摘 | Schnoor C P Euchner M | 1994 | Mathematical Programming1994，66，2： | 1 |
| 3 | Recombinant erythropoietin for the treatment of anemia in inflammatory bowel disease显示文摘 | Schreiber S Howaldt S Schnoor M | 1996 | N Engl J Med1996，334，： | 1 |
| 4 | Advances in phytoremediation 显示文摘 | DIETZ A C SCHNOOR J L | 2001 | Environ health perspect2001，109，1： | 1 |
| 5 | Role of the TDx FLM assay in fetal lung matuity显示文摘 | Herbert WNP Chapman JF Schnoor MM | 1993 | Am J Obstet Gynecol1993，168，3： | 1 |
| 6 | Effect of root-derived substrates on the expression of nah-lux genes in Pseudomonas fluorescens HK44:implications for PAH biodegradation in the rhizosphere显示文摘 | KAMATH R SCHNOOR J L ALVAREZ P J J | 2004 | Environmental Science & Technology2004，38，6： | 1 |
| 7 | Schwarzenbach, Microbial transformations of substituted benzenes during infiltration of river water to groundwater: laboratory column studies显示文摘 | Kuhn E P Colberg P J Schnoor J L | 1985 | Environ Sci Technol1985，19，： | 1 |
| 8 | Phytoremediation of organic and nutrient contaminants显示文摘 | JERALD L SCHNOOR L A LICHT S C | 1995 | Environ Sc & Technol1995，29，7： | 1 |
| 9 | Degradation of TCE, Cr(VI), sulfate, and nitrate mixtures by granular iron in flow-through columns under different microbial conditit ns 显示文摘 | GANDHI S OH B-T SCHNOOR J L | 2002 | Water Research2002，36，8： | 1 |
| 10 | Approaches to estimate the population-based incidence of community acquired pneumonia显示文摘 | Maike Schnoor Jens Hedicke Klaus Dalhoff | 2007 | Journal of Infection2007，55，3： | 1 |
| 11 | Phytoremediation of polychlorinated biphenyls: New trends and promises显示文摘 | Aken B V Correa P A Schnoor J L | 2009 | Environmentol Science & Tech- nology2009，44，8： | 1 |
| 12 | Phytoremediation of organic and nutrient contaminants 显示文摘 | SCHNOOR J L LICHT L A MCCUTCHEON S C | 1995 | Environ Sci Technol1995，29，： | 1 |
| 13 | Phytoremediation,plant uptake of atrazine and role of root exudates显示文摘 | Burken J G Schnoor J L | 1996 | Journal of Environmental Engineering1996，122，11： | 1 |
| 14 | Phytoremediation:plant uptake of atrazine and role of root exudates显示文摘 | BURKEN J G SCHNOOR J L | 1996 | J Environ Qual1996，122，11： | 1 |
| 15 | Phytoremediation technology evaluation report,prepared for Ground-water remediation technologies analysis center显示文摘 | SCHNOOR J L | 1996 | Envi Sci1996，39，： | 1 |
| 16 | Benzopyrene co-metabolism in the presence of plant root extracts and exudates:implications for phytoremediation显示文摘 | RENTZ J A ALVAREZ P J J SCHNOOR J L | 2005 | Environmental Pollution2005，136，： | 1 |
| 17 | Effect of hybrid poplar trees on microbial populations important to hazardous waste bioremediation显示文摘 | JORDAHL J L FOSTER L SCHNOOR J L | 1997 | Environmental Toxicology and Chemistry1997，16，6： | 1 |
| 18 | Phytoremediation of organic and nutrient contaminants显示文摘 | SCHNOOR J L LICHT L A MCCUTCHEON S C | 1995 | Environmental Science and Technology1995，29，7： | 1 |
| 19 | Risk factors for community-acquired pneumonia in German adults : the im- pact of children in the household显示文摘 | Schnoor M Klante T Beckmann M | 2007 | Epidemiol Infect2007，135，8： | 1 |
| 20 | Pesticide transport and biocon- centration model 显示文摘 | SCHNOOR J J MCAVOY D C | 1981 | Journal of the Environmental Engineering Division1981，107，6： | 1 |
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