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| 1 | B lymphocytes regulate airway granulocytic inflammation and cytokine production in a murine model of fungal allergic asthma显示文摘到真菌的促进感受性经常导致是特别地困难的临床上设法的气喘的一种严重形式,导致在这些病人的增加的病态和住院。尽管 B 淋巴细胞可能通过 IgE 的生产加重气喘症状,这些房间可能也在对吸入的真菌的保护的反应是重要的。通过 cytokine 版本和 T 房间相互作用,这些淋巴细胞可能也影响航线墙纤维变性的发展和维护。J H −/− 老鼠为抗体的重链部件缺乏 JH 基因,它为 B 房间功能和幸存是批评的。这些动物在很多有免疫力的回答便于 B 淋巴细胞的角色的说明;然而, J H −/− 老鼠没被用来学习真菌的过敏症。在这研究,我们用曲霉属菌 fumigatus 检验了 B 淋巴细胞的角色模仿被环境真菌的暴露触发的人的航线疾病的鼠科的真菌的高空过敏症模型。我们在敏化的野类型的 BALB/c 和 J 暴露于的 H −/− 老鼠重复了真菌的暴露并且没在大航线附近在航线 hyperresponsiveness,全面肺的发炎或骨胶原免职发现差别。然而, Th2 类型 cytokines IL-4 和 IL-13 的层次显著地在 J 相对 BALB/c 控制的 H −/− 鼠标。由对比,煽动性的 cytokines IL-17A 和 IL-6 的层次显著地在 J H −/− 动物,并且有显著地更柔韧的航线嗜曙红血球过多和 neutrophilia 比在控制动物。一起拿,这些调查结果表明淋巴细胞帮助在肺的分隔空间调整 granulocytic 回答到真菌的暴露的那 B。 | Sumit Ghosh Scott A Hoselton Scott V Asbach Breanne N Steffan Steve B Wanjara Glenn P Dorsam Jane M Schuh | 2015 | Cellular & Molecular Immunology2015，12，2： | 2 |
| 2 | Whole brain radiation therapy with or without stereotactic radiosurgery boost for patients with one to three brain metastases: phase III results of the RTOG 9508 randomised trial显示文摘 | David W Andrews Charles B Scott Paul W Sperduto Adam E Flanders Laurie E Gaspar Michael C Schell Maria Werner-Wasik William Demas Janice Ryu Jean-Paul Bahary Luis Souhami Marvin Rotman Minesh P Mehta Walter J Curran | 2004 | The Lancet . 2004 (9422)2004，，9422： | 2 |
| 3 | Gold and trace element zonation in pyrite using a laser imaging technique: Implications for the timing of gold in orogenic and Carlin- style sediment- hosted deposits 显示文摘 | R R Large L Danyushevsky C Hollit V Maslennikov S Meffer S Gilbert S Bull R Scott P Emsbo H Thomas B Singh J Foster | 2009 | Economic Geology2009，104，5： | 1 |
| 4 | Calcium anidotrihydroborate:a hydrogen storage material显示文摘 | Diyabalanage H V K Shrestha R P Semelsberger TA Scott B L Bowden M E Davis B L Burrell A K | | 0，，47： | 1 |
| 5 | Disappearance of patulin from apple juice fermented by Saccharomyces spp显示文摘 | HARWIG J SCOTT P M KENNEDY B P C | | 0，，01： | 1 |
| 6 | Field N2O, CO2 and CH4 fluxes in relation to tillage, compaction and soil quality in Scotland显示文摘 | Ball B C Scott A Parker J P | 1999 | Soil Tillage Res1999，53，： | 1 |
| 7 | Thymic major histocompatibility complex antigens and the alpha beta T-cell receptor determine the CD4/CD8 phenotype of T cells显示文摘 | Teh HS Kisielow P Scott B | 1988 | Nature1988，335，： | 1 |
| 8 | Features and development of Coot 显示文摘 | Emsley P Lohkamp B Scott W G | 2010 | Acta Crystallogr D Biol Crystallogr2010，66，4： | 1 |
| 9 | The mechanism of intergranular stress corrosion cracking of sensitised austenitic stainless steel in dilute thiosulphate solution 显示文摘 | Stewart J Wells D B Scott P M | 1992 | Corros Sci1992，33，1： | 1 |
| 10 | Field N2O, CO2 and CH4 fluxes in relation to tillage, compaction and soil quality in Scotland 显示文摘 | Ball B C Scott A Parker J P | 1999 | Soil & Tillage Research1999，53，： | 1 |
| 11 | Electrochemical noise measurements of stress corrosion cracking of sensitised austenitic stainless steel in high-purity oxygenated water at 288 °C显示文摘 | STEWART J WELLS D B SCOTT P M WILLIAMS D E | 1992 | Corros Sci1992，33，1： | 1 |
| 12 | Procedural justice, and task performance: The mediating role of intrinsic motivation显示文摘 | ZAPATA-PHELAN C P COLQUITT J A SCOTT B A | 2009 | Organ- izational Behavior and Human Decision Processes2009，108，1： | 1 |
| 13 | Organizational Citizenship Behaviors:A Critical Review of the Theoretical and Empirical Literature and Suggestions for Future Research显示文摘 | Podsakoff P Scott B Paine J Bachrach D | 2000 | Journal of Management2000，26，3： | 1 |
| 14 | Refinement of the 12q14 microdeletion syndrome: primordial dwarfism and developmental delay with or without ostenpoikilosis 显示文摘 | Marl F Hermanns P Maria L Galluzzi F Scott D Lee B | 2009 | EuropJHumanGenet2009，17，10： | 1 |
| 15 | Irradiation of municipal sludge for pathogen control:why or why not?显示文摘 | SCOTT B AHLSTROM P E | 1988 | International Journal of Radiation Applications and Instrumentation Part C Radiation Physics and Chemistry1988，31，13： | 1 |
| 16 | Carbon dioxide transfer over a Central Amazonian rain forest显示文摘 | Malhi Y Nobre A D Grace J Knfijt B Pereira M G P Cull A Scott S | 1998 | Journal of Geophysical Research1998，130，31： | 1 |
| 17 | The relationships between stocking density and welfare in farmed rainbow troul 显示文摘 | Ellis T North B Scott A P | 2002 | Journal of Fish Biology2002，61，： | 1 |
| 18 | Centrifuge study of faulting effects on tunnel显示文摘 | BURRIDGE P B SCOTT R F Hall J F | 1989 | Journal of Geotechnical Engineering1989，115，7： | 1 |
| 19 | Electrorheological damper with annular ducts for seismic protection application 显示文摘 | Makris N Scott A B Douglas P T | 1996 | Smart Materials and Structures1996，5，55： | 1 |
| 20 | p53 protein expression in ductal carcinoma in situ (DCIS) of the breast 显示文摘 | Rajan P B Scott D J Perry R H | 1997 | Breast Cancer Rea Treat1997，42，3： | 1 |
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