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61篇 您的检索式：作者名="Sepp K"

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	题名	作者	年代	出处	被引量
1	Intestinal microbiota and immunoglobulin E responses in 5-year-old Estonian children 显示文摘	Sepp E Julge K Mikelsaar M	2005	Clin Exp Allergy2005，35，：	1
2	Effect of catalyst and polymerization conditions on the preparation of low molecular weight lactic acid polymers显示文摘	Hiltunen K Seppǎlǎ J V Hǎrkǎnen M	1997	Macromolecules1997，30，：	1
3	Metabolomic changes in fatty liver can be modified by dietary protein and calcium during energy restriction显示文摘AIM: To characterise the effect of energy restriction (ER) on liver lipid and primary metabolite profile by using metabolomic approach. We also investigated whether the effect of energy restriction can be further enhanced by modif ication of dietary protein source and calcium. METHODS: Liver metabolomic profile of lean and obese C57Bl/6J mice (n = 10/group) were compared with two groups of weight-reduced mice. ER was performed on control diet and whey protein-based high-calcium diet (whey + Ca). The metabolomicanalyses were performed using the UPLC/MS based lipidomic platform and the HPLC/MS/MS based primary metabolite platform. RESULTS: ER on both diets significantly reduced hepatic lipid accumulation and lipid droplet size, while only whey + Ca diet significantly decreased blood glucose (P < 0.001) and serum insulin (P < 0.01). In hepatic lipid species the biggest reduction was in the level of triacylglycerols and ceramides while the level of cholesterol esters was significantly increased during ER. Interestingly, diacylglycerol to phospholipid ratio, an indicator of relative amount of diabetogenic diglyceride species, was increased in the control ER group, but decreased in the whey + Ca ER group (P < 0.001, vs obese). ER on whey + Ca diet also totally reversed the obesity induced increase in the relative level of lipotoxic ceramides (P < 0.001, vs obese; P > 0.05, vs lean). These changes were accompanied with up-regulated TCA cycle and pentose phosphate pathway metabolites. CONCLUSION: ER-induced changes on hepatic metabolomic profile can be significantly affected by dietary protein source. The therapeutic potential of whey protein and calcium should be further studied.	Taru K Pilvi Tuulikki Seppnen-Laakso Helena Simolin Piet Finckenberg Anne Huotari Karl-Heinz Herzig Riitta Korpela Matej Orei Eero M Mervaala	2008	World Journal of Gastroenterology2008，14，28：	1
4	Immunohistochemical demonstration of carbonic anhydrase isoenzyme VI (CA VI) expression in rat lower airways and lung显示文摘	LEINONEN J S SAARI K A SEPP(A)NEN J M	2004	J Histochem Cytochem2004，52，8：	1
5	Quaternary pollen analysis: recent progress in palaeoecology and palaeoclimatology显示文摘	Sepp H Bennett K D	2003	Progress in Physical Geography2003，27，4：	1
6	Recent primary Toxoplama infection indicated by a low avidity of specific IgG显示文摘	Hedman K Lappalainen M Sepp(a)i(a) I	1989	J Infect Dis1989，159，4：	1
7	Allergy development and the intestinal microflora during the first year of life显示文摘	Bjorksten B Sepp E Julge K	2001	J Allergy Clin Immunnl2001，108，：	1
8	Complement C3 variant and the risk of age-related macular degeneration显示文摘	Yates J R Sepp T Matharu B K	2007	N Engl J Med2007，357，6：	1
9	Intestinal microflora of Estonian and Swedish infants显示文摘	Sepp E Julge K Vasar M	1997	Acta Paediatr1997，86，9：	1
10	Intestinal microflora of Estonian and Swedish infants显示文摘	Sepp E Julge K Vasar M	1997	Acta Paediatr1997，6，9：	1
11	The comparison of susceptibility patterns of Gram-negativeinvasive and non-invasive pathogens in Estonian hospitals显示文摘	Loivukene K Kermes K Sepp E Adamson V Mitt P Jurna M	2006	An-tonie Van Leeuwenhoek2006，89，34：	1
12	Simultaneous determination of fluoroquinolones,sulfonamides andtetracyclines in sewage sludge by pressurized liquid extraction and liquid chromatography electrospray ionization-masss pectrometry显示文摘	LILLENBERG M YURCHENKOS KIPPER K HERODES K PIHLV SEPP K LHMU R NEI L	2009	J Chromatogr:A2009，1216，32：	1
13	Quaternary pollen analysis: recent progress in palaeoeeology and palaeoclimatology显示文摘	Sepp H Bennett K D	2003	Progress in Physical Geogra- phy2003，27，4：	1
14	Intestinal microflora of Estonian and Swedish infants显示文摘	Sepp E Julge K Vasar M	1997	Acta Paediatr1997，86，9：	1
15	Intestinal microflora of Estonian and Swedish infants显示文摘	SEPP E JULGE K VASAR M		0，，09：	1
16	Allergy development and the intestinal microflora during the first year of life显示文摘	Bjorkstén B Sepp E Julge K	2001	J Al- lergy & Clin Immunol2001，108，4：	1
17	Allergy development and the intestinal microflora during the first year of life显示文摘	Bjorksten B Sepp E Julge K	2001	J Aller- gy Clin Immunol2001，108，4：	1
18	Allergy development and intestinal microflora during the first year of life显示文摘	Bj(o)rkstén B Sepp E Julge K	2001	J Allergy Clin Immunol2001，1084，4：	1
19	Allergy development and the intestinal microflora during the first year of life 显示文摘	Bjorksten B Sepp E Julge K	2001	JAllergy Clin lmmunol2001，108，4：	1
20	Allergy development and the intestinal microflora during the first year of life显示文摘	Bjorksten B Sepp E Julge K	2001	J Al- lergy Clin Immunol2001，108，4：	1

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