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| 1 | Broadband THz Sources from Gases to Liquids显示文摘Matters are generally classified within four states:solid,liquid,gas,and plasma.Three of the four states of matter(solid,gas,and plasma)have been used for THz wave generation with short laser pulse excitation for decades,including the recent vigorous development of THz photonics in gases(air plasma).However,the demonstration of THz generation from liquids was conspicuously absent.It is well known that water,the most common liquid,is a strong absorber in the far infrared range.Therefore,liquid water has historically been sworn off as a source for THz radiation.Recently,broadband THz wave generation from a flowing liquid target has been experimentally demonstrated through laser-induced microplasma.The liquid target as the THz source presents unique properties.Specifically,liquids have the comparable material density to that of solids,meaning that laser pulses over a certain area will interact with three orders more molecules than an equivalent cross-section of gases.In contrast with solid targets,the fluidity of liquid allows every laser pulse to interact with a fresh area on the target,meaning that material damage or degradation is not an issue with the high-repetition rate intense laser pulses.These make liquids very promising candidates for the investigation of high-energy-density plasma,as well as the possibility of being the next generation of THz sources. | Yiwen E Liangliang Zhang Anton Tcypkin Sergey Kozlov Cunlin Zhang X.-C.Zhang | 2021 | Ultrafast Science2021，，1： | 3 |
| 2 | Linagliptin alleviates fatty liver disease in diabetic db/db mice显示文摘AIM To study the effects of linagliptin on the structural signs of non-alcoholic fatty liver disease(NAFLD) in db/db mice. METHODS Male diabetic db /db mice(BKS.Cg-Dock7m+/+Leprdb/J) aged 10 wk received the dipeptidyl peptidase 4(DPP4) inhibitor linagliptin(10 mg/kg) or saline as a placebo once per day by gavage for 8 wk. Intact db/db mice served as controls. Structural changes in the liver were analyzed from light and electron microscopic images of sections from intact, placebo-treated and linagliptin-treated animals. We estimated the changes in hepatocytes, sinusoidal cells, liver microvasculature and lymphatic roots. Hepatic staining for lymphatic vessel endothelial hyaluronan receptor-1(LYVE-1) was assessed by immunohistochemistry. RESULTS In 18-wk-old diabetic mice, liver steatosis(predominantly microvesicular and mediovesicular steatosis) was accompanied by dilation of the roots of the lymphatic system, interlobular blood vessels and bile canaliculi. Compared to saline-treated mice, linagliptin-treated mice exhibited a reduction in the mean numeral densities of hepatocytes with lipid droplets(92.4% ± 1.7% vs 64.9% ± 5.8% per field of view, P = 0.0002) and a lower proportion of hepatocytes with a high density of lipid droplets(20.7% ± 3.6% vs 50.4% ± 3.1%, P = 0.0007). We observed heterogeneous hepatocytes and relatively preserved cell structures in the linagliptin group. Dilation of blood and lymphatic vessels, as well as ultrastructural changes in the hepatocyte endoplasmic reticulum and mitochondria, were alleviated by linagliptin treatment. In intact and placebo-treated mice, immunohistochemical staining for LYVE-1 was observed in the endothelial cells of interlobular lymphatic vessels and on the membranes of some endothelial sinusoidal cells. We observed an enlarged LYVE-1 reaction area in linagliptin-treated mice compared to intact and placebo-treated mice. The improvement in the structural parameters of the liver in linagliptin-treated mice was independent to changes in the plasma glucose levels. CONCLUSION The DPP4 inhibitor linagliptin alleviates liver steatosis and structural changes in the hepatic microvasculature and lymphatic roots in a model of NAFLD in diabetic db/db mice. | Svetlana V Michurina Irina Ju Ishenko Vadim V Klimontov Sergey A Archipov Natalia E Myakina Marina A Cherepanova Eugenii L Zavjalov Galina V Koncevaya Vladimir I Konenkov | 2016 | World Journal of Diabetes2016，7，19： | 2 |
| 3 | 日地物理学在生物周期研究中的应用(英文)显示文摘在过去的半个世纪中,对于感光生物的近日、近年周期的研究已深入到了基因层面。而在近二十年中,大量的研究主要集中在处于某些太阳周期和地理区域的非感光生物的周期中。生物圈的空间天气在时间和空间上的差别变得越加明显,这一发现指出了日-地-月相互作用生物学中非常重要的物理标记,对于物理学家来说极有意义。通过望远镜的观测记录,这一生物学迹象首次向我们描述了地磁场与精确的七日周期不同的接近七日的周期,以及太阳风和太阳磁场的近年周期。因此,目前需要对以前的和现在新发现的理论、机制进行重新定位,将以前单独的生物和环境节律合并为一个交叉系统,使每一条途径都进一步完善,在适当措施下可同时适用于感光和非感光条件。这些都是值得我们每一个研究者来认真思索的问题。我们也相信不管是关于物理学还是生物圈的研究,随着更多的研究者的努力,都将取得巨大的进步。 | Franz Halberg Germaine Cornélissen George Katinas Sergey Chibisov Dan Holley Jerzy Czaplicki Kuniaki Otsuka Earl E Bakken | 2007 | 西部医学2007，19，2： | 2 |
| 4 | Computer simulations of electrokinetic injection techniques in microfluidic devices 显示文摘 | Sergey V E Stephen C J Ramsey J M | 2000 | Anal Chem2000，72，15： | 1 |
| 5 | Nonlinear control of servo-systems actuated by permanent magnet synchronous motors显示文摘 | SERGEY E L | 1998 | Automation1998，34，10： | 1 |
| 6 | Production of LAPO4 coatings using a novel ultrasonically-assisted plating technique显示文摘 | Komarov Sergey V Romankov Sergey E Son Sang Han | 2008 | Surface & Coatings Technology2008，202，21： | 1 |
| 7 | Conductometric tyrosinase biosensor for the detection of diuron,atrazine and its main metabolites显示文摘 | Tuan M E Sergei V D Minh C V | 2004 | Talanta2004，63，： | 1 |
| 8 | Control of high performance induction motors: theory and practice 显示文摘 | SERGEY E L | 2001 | Energy Conversion and Management2001，42，7： | 1 |
| 9 | FOG-2: A novel GATA-family cofactor related to multitype Zinc-finger proteins Friend of GATA-1 and U-shaped显示文摘 | G TEVOSIAN ANNE E | 1999 | Proc Natl Acad Sci USA1999，96，： | 1 |
| 10 | Nonlinear optimization framework for image-based modeling on programmable graphics hardware显示文摘 | Hillesland Karl E Molinov Sergey Grzeszczuk Radek | 2003 | ACM Transactions on Graphics2003，22，3： | 1 |
| 11 | Electromechanical flight actuators for advanced flight vehicles显示文摘 | Sergey E L | 1999 | IEEE Trans AES1999，35，2： | 1 |
| 12 | The oxidation of heterocyclic amines to nitro compounds using dinitrogen pentoxide 显示文摘 | Aleksandr M Churakov Sergei E Semenov | 1995 | Mendeleeve communication1995，，： | 1 |
| 13 | Measurement of the concentration ratio for <SUP>13</SUP>? and <SUP>12</SUP>? isotopes at atmospheric pressure by carbon dioxide absorption of diode laser radiation at ~2 μm显示文摘 | E S Mironchuk I V Nikolaev Vladimir N Ochkin S S Rodionova Maksim V Spiridonov Sergei N Tskhai | 2009 | Quantum Electronics2009，，4： | 1 |
| 14 | Water quality and ecology of water bodies in urban territories: St, Petersburg as a case study显示文摘 | Sergei K Ludmila E | 1998 | Regulated Rivers: Research & Management1998，14，： | 1 |
| 15 | Biological and medical significance of calcium phosphates显示文摘 | Sergey V Dorozhkin M E | 2002 | Angew Chem Int Ed2002，41，： | 1 |
| 16 | Development ofChemiluminescent ELISAs to DDT and It s Metabolites ir Food and Environmental Samples显示文摘 | Alexandra E Botchkareva Sergei A Eremin Angel Montoya el al | 2003 | Journal of Immunological Methods2003，283，： | 1 |
| 17 | The identi- fication and characterization of IbpA, a novel ct-crystallin- type heat shock protein from mycoplasma显示文摘 | Innokentii E V Sergei A L Valentin A M | 2012 | Cell Stress Chap- erones2012，17，： | 1 |
| 18 | Recent progress indevelopment of non-ATP competitive small-molecule inhibitors of protein kinases 显示文摘 | KISELYOV A BALAKIN K V SERGEY E | 2006 | Mini Review in Medicinal Chemistry2006，6，6： | 1 |
| 19 | Review overview of recent developments in the flame retardancy of polycarbonates 显示文摘 | SERGEI V LEVCHIK WEIL E D | 2005 | Polymer2005，54，3： | 1 |
| 20 | Control of high performance induction motors: theory and practice显示文摘 | SERGEY E L | 2001 | Energy Conversion and Management2001，42，7： | 1 |
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