|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Risk for emerging bipolar disorder, variants, and symptoms in children with attention deficit hyperactivity disorder, now grown up显示文摘AIM: To determine the prevalence of bipolar disorder(BD) and sub-threshold symptoms in children with attention deficit hyperactivity disorder(ADHD) through 14 years' follow-up, when participants were between 21-24 years old.METHODS: First, we examined rates of BD type Ⅰ?and Ⅱ diagnoses in youth participating in the NIMH-funded Multimodal Treatment Study of ADHD(MTA). We used the diagnostic interview schedule for children(DISC), administered to both parents(DISC-P) and youth(DISCY). We compared the MTA study subjects with ADHD(n = 579) to a local normative comparison group(LNCG, n = 289) at 4 different assessment points: 6, 8, 12, and 14 years of follow-ups. To evaluate the bipolar variants, we compared total symptom counts(TSC) of DSM manic and hypomanic symptoms that were generated by DISC in ADHD and LNCG subjects. Then we sub-divided the TSC into pathognomonic manic(PM) and non-specific manic(NSM) symptoms. We compared the PM and NSM in ADHD and LNCG at each assessment point and over time. We also evaluated the irritability as category A2 manic symptom in both groups and over time. Finally, we studied the irritability symptom in correlation with PM and NSM in ADHD and LNCG subjects.RESULTS: DISC-generated BD diagnosis did not differ significantly in rates between ADHD(1.89%) and LNCG 1.38%). Interestingly, no participant met BD diagnosis more than once in the 4 assessment points in 14 years. However, on the symptom level, ADHD subjects reported significantly higher mean TSC scores: ADHD 3.0; LNCG 1.7; P < 0.001. ADHD status was associated with higher mean NSM: ADHD 2.0 vs LNCG 1.1; P < 0.0001. Also, ADHD subjects had higher PM symptoms than LNCG, with PM means over all time points of 1.3 ADHD; 0.9 LNCG; P = 0.0001. Examining both NSM and PM, ADHD status associated with greater NSM than PM. However, Over 14 years, the NSM symptoms declined and changed to PM over time(df 3, 2523; F = 20.1; P < 0.0001). Finally, Irritability(BD DSM criterion-A2) rates were significantly higher in ADHD than LNCG(χ2 = 122.2, P < 0.0001), but irritability was associated more strongly with NSM than PM(df 3, 2538; F = 43.2; P < 0.0001).CONCLUSION: Individuals with ADHD do not appear to be at significantly greater risk for developing BD, but do show higher rates of BD symptoms, especially NSM. The greater linkage of irritability to NSM than to PM suggests caution when making BD diagnoses based on irritability alone as one of 2(A-level) symptoms for BD diagnosis, particularly in view of its frequent presentation with other psychopathologies. | Ahmed Z Elmaadawi Peter S Jensen L Eugene Arnold Brooke SG Molina Lily Hechtman Howard B Abikoff Stephen P Hinshaw Jeffrey H Newcorn Laurence Lee Greenhill James M Swanson Cathryn A Galanter | 2015 | World Journal of Psychiatry2015，5，4： | 3 |
| 2 | 失眠在创伤后应激障碍与高血压关系中的作用显示文摘创伤后应激障碍(posttraumatic stress disorder,PTSD)与高血压发病相关。PTSD还与失眠症相关,尽管对两者关系知之甚少,但它会增加高血压患病风险。失眠是否会增加PTSD相关的高血压风险目前仍是未知的。方法:研究者检索了1109名女性退伍军人队列研究(women veterans cohort study)参与者[平均年龄为(43.8±10.9)岁;52%为女性,81%为白人]的问卷调查和电子健康记录数据,评估其PTSD症状严重程度、近期失眠症状与高血压的横断面关系。 | 周卫(译) 袁源(审校) Gaffey AE Redeker NS Rosman L Mullington MJ Brandt CA Haskell SG Burg MM | 2020 | 中华高血压杂志2020，28，9： | 3 |
| 3 | 低浓度胰岛素样生长因子Ⅱ可以预报正常体重2型糖尿病患者的体重增加显示文摘 | Heald AH Karvestedt L Anderson SG 菅鑫妍 | 2006 | 中国处方药2006，5，6： | 3 |
| 4 | Comparative screening for thyroid disorders in old age in areas of iodine deficiency, long‐term iodine prophylaxis and abundant iodine intake显示文摘 | IstvánSzabolcs JanPodoba JoachimFeldkamp OrsolyaDohán IldikóFarkas MihálynéSajgó Krisztina I.Takáts MiklósGóth LászlóKovács KatalinKressinszky PeterHnilica GézaSzilágyi | 2003 | Clinical Endocrinology2003，，1： | 2 |
| 5 | QRS duration and shortening to predict clinical response to cardiac resynchronization therapy in patients with end-stage heart failure显示文摘 | Molhoek SG Van Erven L Bootsma M | 2004 | Pacing Clin Eleetrophysiol2004，27，3： | 1 |
| 6 | Astrocyte elevated gene-1 activates cell survival pathways through PI3K-Akt signaling显示文摘 | Lee SG Su ZZ Emdad L | 2008 | Oncogene2008，27，8： | 1 |
| 7 | Hepatic enzymes, the metabolic syndrome, and the risk of type 2 diabetes in older men 显示文摘 | Wannamethee SG Shaper AG Lennon L | 2005 | Diabetes Care2005，28，12： | 1 |
| 8 | Angiotensin Ⅱ contributes to arterial compliance in congestive heart failure显示文摘 | Lage SG Kopel L Medeiros CC | 2002 | Am J Physiol Heart Circ Physiol2002，283，4： | 1 |
| 9 | Virulence factors of porphyromonas gingivalis显示文摘 | Holt SC Kesavalu L Walker SG | 2000 | Periodontology2000，20，6： | 1 |
| 10 | Astroeyte elevated gene - 1 : a no- vel target for human glioma therapy 显示文摘 | Emdad L Sarkar D Lee SG | 2010 | Mol Cancer Ther2010，9，1： | 1 |
| 11 | Oxygen toxicity显示文摘 | Bn an ('L Jenkinson SG | 1988 | Cliu Chest Med1988，9，1： | 1 |
| 12 | Reliability of the penetration aspiration scale with flexible endoscopic evaluation of swallowing显示文摘 | Butler SG Markley L Sanders B | 2015 | Ann Otol Rhinol Laryngol2015，124，6： | 1 |
| 13 | Molecular characterization of the low-affinity IgE receptor Fc epsilonRII/ CD23 expressed by human eosinophils 显示文摘 | Abdelilah SG Bouchaib L Morita M | 1998 | Int Immunol1998，10，： | 1 |
| 14 | Prostaglandins as modulators of immunity显示文摘 | Harris SG Padilla J Koumas L | 2002 | Trends Immunol2002，23，： | 1 |
| 15 | Effects of intensive blood pressure lowering and low-dose aspirin in patients with hypertension: principal results of the hypertension optimal treatment (HOT) randomised trial显示文摘 | Hansson L Zanchetti A Carruthers SG | 1998 | Lancet1998，351，： | 1 |
| 16 | Effect of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the hypertension optimal treatment (HOT) ransomised trial显示文摘 | Hansson L Zanchetti A Carruthers SG Dahlof B Elmfeldt D Julius S MenardJ Rahn KH Wedel H Westerling S | 1998 | Lancet1998，351，21： | 1 |
| 17 | Effects of methylenetetrahydrofolate reductase gene polymorphisms on toxicities during consolidation therapy in pediatric acute lymphoblastic leukemia in a Chinese population显示文摘 | Liu SG Li ZG Cui L | | 0，，06： | 1 |
| 18 | Effects of intensive blood- pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial显示文摘 | Hansson L Zanchetti A Carruthers SG | 1998 | Lancet1998，351，： | 1 |
| 19 | Trunk injection : an alternative technique for pesticide deliveryin apples 显示文摘 | VANWOERKOM A H ACIMOVIC SG SUNDIN GW et a l 2014 | 2014 | Orig Res Art Crop Prot2014，65，： | 1 |
| 20 | Idiopathic iso- sexual central precocious puberty:magnetic resonance findings in 30 patients 显示文摘 | Robben SG Oostdijk W Drop S L | 1995 | Br J Radiol1995，68，805： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员