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| 1 | The Chromosome-Level Reference Genome of Tea Tree Unveils Recent Bursts of Nonautonomous LTR Retrotransposons in Driving Genome Size Evolution显示文摘Dear Editor,The tea tree Camellia sinensis,a member of the genus Camellia in the Theaceae family,includes two major cultivated varieties,C.sinensis var.assamica(CSA\Assam type)and C.sinensis var.sinensis(CSS;Chinese type)(Ming and Bartholomew,2007).Due to the high economic importance of the tea tree,considerable efforts have been made to explore genetic basis of the biosynthesis of natural metabolites that determine health benefits and diverse tea flavors(Shi et al.,2011;Li et al.,2011;Li et al.,2015;Xia et aL,2017;Liu et al.,2019). | Qun-Jie Zhang Wei L i Kui Li Hong Nan Cong Shi Yun Zhang Zhang-Yan Dai Yang-Lei Lin Xiao-Lan Yang Yan Tong Dan Zhang Cui Lu Li-Ying Feng Chen-Feng Wang Xiao-Xin Liu Jian-An Huang Wen-Kai Jiang Xing-Hua Wang Xing-Cai Zhang Evan E.Eichler Zhong-Hua Liu and Li-Zhi Gao | 2020 | Molecular Plant2020，13，7： | 27 |
| 2 | Granulocyte-macrophage colony-stimulating factor (GM-CSF) and T-cell responses: what we do and don't know显示文摘Granulocyte 巨噬细胞刺激殖民地的因素(GM-CSF ) 是一个重要造血的生长因素和有免疫力的调节的人。GM-CSF 也在各种各样的传播白血球的功能的活动有深刻效果。它被许多房间类型在收到有免疫力的刺激之上包括 T 房间,巨噬细胞, endothelial 房间和成纤维细胞生产。尽管 GM-CSF 局部地被生产,它能以一种 paracrine 方式行动到在主人防卫提高他们的功能的成员传播 neutrophils,单核白血球和淋巴细胞。最近的集中的调查为它增加树枝状的房间(DC ) 成熟和功能以及巨噬细胞活动的能力作为一个有免疫力的助手在 GM-CSF 的应用程序上被集中。在经历化疗的癌症病人对待嗜中性白血球减少症临床上被使用,在在治疗期间的爱滋病病人,并且在在骨髓移植以后的病人。有趣地, GM-CSF-deficient 老鼠的造血的系统看起来正常;最重要的变化在一些特定的 T 房间回答。尽管 GM-CSF 的分子的克隆用 T 房间的 cDNA 图书馆被执行, T 房间在激活以后生产 GM-CSF,是众所周知的,在 T 房间功能上有在由 T 房间和它的效果的生产的这 cytokine 的系统的调查的缺乏。在这篇文章,我们将在 T 房间主要集中于 GM-CSF 的免疫生物学。 | Yufang Shi Catherine H Liu Arthur I Roberts Jyoti Das Guangwu Xu Guangwen Ren Yingyu Zhang Liying Zhang Zeng Rong Yuan Hung Sheng William Tan Gobardhan Das Satish Devadas | 2006 | Cell Research2006，16，2： | 22 |
| 3 | Risk factors of intrahepatic cholangiocarcinoma in patients with hepatolithiasis:a case-control study显示文摘BACKGROUND:Why 3.3% to 10% of all patients with hepatolithiasis develop intrahepatic cholangiocarcinoma (ICC) remains unknown.We carried out a hospital-based case-control study to identify risk factors for the development of ICC in patients with hepatolithiasis in China.METHODS:Eighty-seven patients with pathologically diagnosed hepatolithiasis associated with ICC and 228 with hepatolithiasis alone matched by sex,age (±2 years),hospital admittance and place of residence were interviewed during the period of 2000-2008.Odds ratios (OR) and 95% confidence intervals (CI) were calculated for each risk factor.RESULTS:Among the patients with hepatolithiasis associated with ICC,the mean age was 57.7 years and 61.0% were female Univariate analysis showed that the significant risk factors for ICC development in hepatolithiasis were smoking,family history of cancer,appendectomy during childhood (under age 20),and duration of symptoms >10 years.In multivariate stepwise logistic regression analysis,smoking (OR=1.931,95% CI:1.000-3.731),family history of cancer (OR=5.175,95% CI:1.216-22.022),and duration of symptoms >10 years (OR=2.348 95% CI:1.394-3.952) were independent factors.CONCLUSION:Smoking,family history of cancer and duration of symptoms >10 years may be risk factors for ICC in patients with hepatolithiasis. | Zhen-Yu Liu,Yan-Ming Zhou,Le-Hua Shi and Zheng-Feng YinAuthor Affiliations:Molecular Oncology Laboratory and Department of Comprehensive Treatment I,Eastern Hepatobiliary Surgery Hospital,Second Military Medical University,Shanghai 200438,China Department of Hepato-Biliary-Pancreato-Vascular Surgery,First Affiliated Hospital,Xiamen University,Xiamen 361003,China | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，6： | 21 |
| 4 | Structural insights into SUN-KASH complexes across the nuclear envelope显示文摘nucleoskeleton 和细胞骨架(LINC ) 的连接器建筑群由阳光和 KASH 包含域的蛋白质组成并且衔接原子信封的内部、外部的膜。LINC 建筑群在原子放,房间极化和细胞的僵硬起关键作用。以前,我们报导了人的 SUN2 的 homotrimeric 结构。我们现在决定了人的 SUN2-KASH 建筑群的水晶结构。在复杂结构, SUN 领域 homotrimer 绑在三独立 “ hook”相似 KASH 肽。在建筑群的 SUN 领域的全面符合构造非常处于它的 apo 状态类似于 SUN 领域。一个主要 conformational 变化包含 KASH 固定的阳光领域的 AA'-loop,它重排形成微型 β与 KASH 肽交往的表。KASH 领域的磅主题在 SUN 领域的 homotrimeric 接口上紧适合进一个恐水病的衣袋,我们它称为双性人衣袋。而且, SUN 领域 homotrimer 三明治的二邻近的 protomers 由结合的恐水病的相互作用和氢的 KASH 领域。这些有约束力的地点的变化在 vitro 破坏或减少在 SUN 和 KASH 域之间的协会。另外, transfection 野类型,然而并非变异, SUN2 在 Ovcar-3 房间支持房间移植。这些结果提供 LINC 建筑群的一个结构的模型,它为另外的学习是必要的物理、功能在细胞质和核质之间联合。 | Wenjia Wang Zhubing Shi Shi Jiao Cuicui Chen Huizhen Wang Guoguang Liu Qiang Wang Yun Zhao Mark I Greene Zhaocai Zhou | 2012 | Cell Research2012，22，10： | 3 |
| 5 | Regulation of macrophage inflam matory protein-2 gene ex pression by oxidative stress in rat alveolar macrophagec显示文摘 | SHI MM Chong I Godleski JJ | 1999 | Im munology1999，97，： | 1 |
| 6 | Random flow genera- tion technique for large eddy simulations and particle-dy- namics modeling显示文摘 | SMIRNOV A SHI S CELIK I | 2001 | Journal of Fluids Engineering2001，123，2： | 1 |
| 7 | Direct mapping of hippocampal surfaces with intrinsic shape context显示文摘 | Shi Y G Thompson P M de Zubicaray G I | | 0，，03： | 1 |
| 8 | Coal liquefaction technoln- gies--development in China and challenges in chemical reaction engineering显示文摘 | I IU Z Y SHI S D LI Y W | 2010 | Chemical Engineering Science2010，65，1： | 1 |
| 9 | Anthocyanin pigments of sweet potatoes-Ipomoea batatas显示文摘 | Shi Z Bassa I A Gabriel S L | 1992 | Journal of Food Science1992，57，75： | 1 |
| 10 | Expression and antigenicity of survivin, an inhibitor of apoptosis family member, in bladder cancer: implications for specific immunotherapy显示文摘 | Kitamura H Torigoe T Honma I Asanuma H Nakazawa E Shi mozawa K | 2006 | Urology2006，67，： | 1 |
| 11 | Random flow generation technique for large eddy simulations and particle-dynamics modeling显示文摘 | Smirnov R Shi S Celik I | 2001 | Journal of Fluids Engineering2001，123，： | 1 |
| 12 | The influence of NF-kappaB signal-transduction pathways on the murine inner ear by acoustic overstimulation显示文摘 | Yamamoto H Omelchenko I Shi X | 2009 | J Neurosci Res2009，87，8： | 1 |
| 13 | The interfacial characterization of oxidized SiC(p)/2014Al composites显示文摘 | SHI Zhong-liang YANG J M LEE J C ZHANG Di LEE H I WU Ren-jie | 2001 | Materials Science and Engineering A2001，303，： | 1 |
| 14 | Material properties and fabrication parameters in selective laser sintering process显示文摘 | Gibson I Shi D P | 1997 | Rapid Prototyping Journal1997，3，4： | 1 |
| 15 | LES of bubble dynamics in wake flows显示文摘 | Smirnov A Celik I Shi S | 2005 | Computers and Fluids2005，34，： | 1 |
| 16 | Production of antifungal compounds from chitin by Bacillus subtilis显示文摘 | Wang S L Shi I L Wang C H Tseng K C Chang W T Twu Y K Ro J J Wang C L | 2002 | Enzyme and Microbial Technology2002，31，3： | 1 |
| 17 | The genomic sequence of the accidental pathogen Legionella pne umophila显示文摘 | Chien M Morozova I Shi S | 2004 | Science2004，305，： | 1 |
| 18 | Straight wing vertical axis wind turbines a flow analysis 显示文摘 | Horiuchi K U shi Yama I Seki K | 2005 | Wind Engineering2005，，29： | 1 |
| 19 | Proteomic analysis of saliva from patients withoral chronic graft-versus-host disease显示文摘 | DEVIC I SHI M SCHUBERT M M | 2014 | BiolBlood Marrow Transplant2014，20，10： | 1 |
| 20 | Upregulated iNOS and oxidative damage to the cochlear stria vascularis due to noise stress 显示文摘 | Shi X Nuttall A I | 2003 | Brain Res2003，967，12： | 1 |
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