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| 1 | Smashing Tissue Extraction and HPLC Determination of Active Saponins from Different Parts of Panax notoginseng显示文摘Objective To optimize the extraction technology used for extracting active saponins from the roots,fibrous roots,basal part of stems,root verrucae,fruits,flowers,stems,and leaves of Panax notoginseng based on the contents of ginsengsides Rg1,Rb1,and notoginsengside R1 as evaluation indexes.Methods Different parts of P.notoginseng were extracted by smashing tissue extraction(STE),ultrasound extraction,and reflux extraction.The contents of ginsengsides Rg1,Rb1,and notoginsengside R1 in 24 kinds of extracts were determined by HPLC-UV.Hypersil C18 column(200 mm × 4.6 mm,5 μm) and acetonitrile-warter(20:80 for 30 min→45:55 for 18 min→70:30 for 2 min→80:20 for 10 min→100:0) were used;UV detector was set at 203 nm;The flow rate was set at 1.0 mL/min.Results STE was the most efficient technology with the highest yield of active saponins among the three tested extraction technologies.Conclusion STE is a fast,effective,and economical method to extract the active saponins from different parts of P.notoginseng.It could significantly shorten the extraction time and simplify the determination of the pre-processing work on identifying P.notoginseng.Such quick and effective extraction provides a powerful tool for analyzing P.notoginseng in the future. | Sheng-ming SHI Yan-ze LIU Wen TAI Chang-qing CHEN Yu-qing ZHAO | 2012 | Chinese Herbal Medicines2012，4，4： | 24 |
| 2 | Transduction of Fas gene or Bcl-2 antisense RNA sensitizes cultured drug resistant gastric cancer cells to chemotherapeutic drugs显示文摘INTRODUCTIONChemotherapyisoneofthemajormethodsintumortreatment,butitoftendoesnotworkduetomultidrugresistance(MDR).Recentstudi... | XIAO Bing, SHI Yong Quan, ZHAO Yan Qiu, YOU Han, WANG Zuo You, LIU Xian Ling, YIN Fang, QIAO Tai Dong and FAN Dai Ming | 1998 | World Journal of Gastroenterology1998，4，5： | 24 |
| 3 | Shear-wave splitting in the crust:Regional compressive stress from polarizations of fast shear-waves显示文摘When propagating through anisotropic rocks in the crust,shear-waves split into faster and slower components with almost orthogonal polarizations.For nearly vertical propagation the polarization of fast shear-wave(PFS)is parallel to both the strike of the cracks and the direction of maximum horizontal stress,therefore it is possible to use PFS to study stress in the crust.This study discusses several examples in which PFS is applied to deduce the compressive stress in North China,Longmenshan fault zone of east edge of Tibetan plateau and Yunnan zone of southeast edge of Tibetan plateau,also discusses temporal variations of PFS orientations of 1999 Xiuyan earthquake sequences of northeastern China.The results are consistent to those of other independent traditional stress measurements.There is a bridge between crustal PFS and the crustal principal compressive stress although there are many unclear disturbance sources.This study suggests the PFS results could be used to deduce regional and in situ principal compressive stress in the crust only if there are enough seismic stations and enough data.At least,PFS is a useful choice in the zone where there are a large number of dense seismic stations. | Yuan Gao Yutao Shi Jing Wu Lingxue Tai | 2012 | Earthquake Science2012，25，1： | 20 |
| 4 | Genetic aberration in primary hepatocellular carcinoma:correlation between p53 gene mutation and loss-of-heterozygosity on chromosome 16q21-q23 and 9p21-p23显示文摘To elucidate the molecular pathology underlying the development of hepatocellular carcinoma (HCC), we used 41 highly polymorphic microsatellite markers to examine 55 HCC and corresponding non-tumor liver tissues on chromosome 9, 16 and 17. Loss-of-heterozygosity (LOH) is observed with high frequency on chromosomal region 17p13 (36/55, 65%), 9p21-p23 (28/55, 51%), 16q21-q23 (27/55, 49%) in tumors. Meanwhile, microsatellite instability is rarely found in these microsatellite loci. Direct sequencing was performed to detect the tentative mutation of tumor suppressor genes in these regions: p53, MTS1/p16, and CDH1/E-cadherin. Within exon 5-9 of p53 gene, 14 out of 55 HCC specimens (24%) have somatic mutations, and nucleotide deletion of this gene is reported in HCC for the first time. Mutation in MTS1/pl6 is found only in one tumor case. We do not find mutations in CDH1/E-cadherin. Furthermore, a statistically significant correlation is present between p53 gene mutation and loss of chromosome region 16q21q23 and 9p21-p23, which indicates that synergism between p53 inactivation and deletion of 16q21-q23 and 9p21-p23 may play a role in the pathogenesis of HCC. Genetic aberration in hepatocellular | WANG GANG CHANG HUI HUANG YAN ZHAO LING CAI YING WANG SHI JIN XIU ZHENG WEN JIANG SHUANG YANG XIN TAI ZHAO WEI HUANG JIAN REN GU | 2000 | Cell Research2000，10，4： | 7 |
| 5 | A novel receptor-binding domain (RBD)-based mRNA vaccine against SARS-CoV-2显示文摘Dear Editor,The pandemic of coronavirus disease 2019(COVID-19)caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)highlights the need to develop effective and safe vaccines.Similar to SARS-CoV,SARS-CoV-2 recognizes angiotensin-converting enzyme 2(ACE2)as receptor for host cell entry.1,2 SARS-CoV-2 spike(S)protein consists of S1,including receptor-binding domain(RBD),and S2 subunits.3,4 We previously demonstrated that RBDs of SARS-CoV and MERS-CoV serve as important targets for the development of effective vaccines. | Wanbo Tai Xiujuan Zhang Aleksandra Drelich Juan Shi Jason CHsu Larry Luchsinger Christopher D.Hillyer Chien-Te KTseng Shibo Jiang Lanying Du | 2020 | Cell Research2020，30，10： | 5 |
| 6 | Cross-neutralization of SARS coronavirus-specific antibodies against bat SARS-like coronaviruses显示文摘Dear Editor,The 2002–2003 global pandemic caused by severe acute respiratory syndrome coronavirus(SARS-CoV)infected around 8,000 people with 10%mortality(http://www.who.int/csr/sars/en/).The virus has a positivestranded RNA genome that encodes a large polyprotein(1a and 1ab),four structural proteins,including spike(S), | Lei-Ping Zeng Xing-Yi Ge Cheng Peng Wanbo Tai Shibo Jiang Lanying Du Zheng-Li Shi | 2017 | Science China(Life Sciences)2017，60，12： | 4 |
| 7 | Keggin type heteropolyacids-catalyzed synthesis of quinoxaline derivatives in water显示文摘Keggin 类型 heteropolyacids 被发现是为从有在水里的优秀收益的 1,2-dicarbonyl 混合物的 1,2 肼的冷凝作用的生物学上活跃的 quinoxaline 衍生物的合成的有效、可重用的催化剂。这个方法以催化剂,底层的一个宽范围,和简单病情的检查过程的小数量提供一个新、有效的协议。 | Tai Kun Huang Lin Shi Rui Wang Xing Zhou Guo Xiao Xia Lu | 2009 | Chinese Chemical Letters2009，20，2： | 4 |
| 8 | Effects of nano-sized Ag reinforcing particulates on the microstructure of Sn-0.7Cu solder joints显示文摘Composite solders were prepared by mechanically dispersing different volumes of nano-sized Ag particles into the Sn-0.7Cu eutectic solder. The effects of Ag particle addition on the microstructure of Sn-0.7Cu solder joints were investigated. Besides, the effects of isothermal aging on the microstructural evolution in the interfacial intermetallic compound (IMC) layer of the Sn-0.7Cu solder and the composite solder reinforced with 1vol% Ag particles were analyzed, respectively. Experimental results indicate that the growth rate of the interfacial IMC layer in the Ag particles reinforced composite solder joint is much lower than that in the Sn-0.7Cu solder joint during isothermal aging. The Ag particles reinforced composite solder joint exhibits much lower layer-growth coefficient for the growth of the IMC layer than the corresponding solder joint. | Feng Tai Fu Guo Zhi-dong Xia Yong-ping Lei Yao-wu Shi | 2009 | International Journal of Minerals,Metallurgy and Materials2009，16，6： | 4 |
| 9 | One-bath synthesis of hydrophilic molecularly imprinted quantum dots for selective recognition of chlorophenol显示文摘简单一个洗澡策略被开发了综合新奇 CdTe@SiO2@MIP (分子地印了并且 silica-functionalized CdTe 量点, MISFQD ),在哪个硅石壳在 CdTe 量点( CdTe@SiO2 QD )的表面上是涂的然后为 4-chlorophenol ( 4-CP )的选择识别的聚合物作为 stabilizer 用 mercaptoacetic 酸在 CdTe@SiO2 QD 的表面上被构造, 3-aminopropyl-trimethoxysilane ( APTES )同样功能的单体和 tetraethoxysilane ( TEOS )作为交叉连接一CdTe@SiO2@MIP 的结构被 ultravioletvisible 吸收,荧光,英尺红外光谱和粉末 X 光检查衍射分析。CdTe@SiO2@MIP 的应用程序和描述被实验调查。所有结果显示 CdTe@SiO2@MIP 罐头有选择地认出 4-chlorophenol。 | Tai Ye Shi Yan Lu Qin Qin Hu Xin Jiang Guo Fen Wei Jing Jing Wang Jian Quan Lu | 2011 | Chinese Chemical Letters2011，22，10： | 2 |
| 10 | Ultra-light and flexible pencil-trace anode for high performance potassium-ion and lithium-ion batteries显示文摘Engineering design of battery configurations and new battery system development are alternative approaches to achieve high performance batteries. A novel flexible and ultra-light graphite anode is fabricated by simple friction drawing on filter paper with a commercial 8 B pencil.Compared with the traditional anode using copper foil as current collector, this innovative current-collector-free design presents capacity improvement of over 200% by reducing the inert weight of the electrode. The as-prepared pencil-trace electrode exhibits excellent rate performance in potassium-ion batteries(KIBs), significantly better than in lithium-ion batteries(LIBs), with capacity retention of 66% for the KIB vs. 28% for the LIB from 0.1 to 0.5 A g^(-1). It also shows a high reversible capacity of ~230 mAh g^(-1) at 0.2 A g^(-1), 75% capacity retention over350 cycles at 0.4 A g^(-1)and the highest rate performance(based on the total electrode weight) among graphite electrodes for K+ storage reported so far. | Zhixin Tai Yajie Liu Qing Zhang Tengfei Zhou Zaiping Guo Hua Kun Liu Shi Xue Dou | 2017 | Green Energy & Environment2017，2，3： | 2 |
| 11 | Dovitinib demonstrates antitumor and antimetastatic activities in xenograft models of hepatocellular carcinoma显示文摘 | Hung Huynh Pierce Kah Hoe Chow Wai Ming Tai Su Pin Choo Alexander Yaw Fui Chung Hock Soo Ong Khee Chee Soo Richard Ong Ronald Linnartz Michael Ming Shi | 2011 | Journal of Hepatology2011，，3： | 2 |
| 12 | Graph cuts for curvature based image denoising显示文摘 | Bae E Shi J Tai X C | | 0，，5： | 1 |
| 13 | Facile preparation of UiO 66 nanoparticles with tunable sizes in a continuous flow microreactor and its application in drug deliv- ery显示文摘 | TAI Shi jun ZHANG Wei-quan ZHANG Jin-sheng | 2016 | Mieroporous and Mesoporous Materials2016，220，： | 1 |
| 14 | Deposition and properties of highly(100)-oriented barium titanate thin films on LaNiO3 electrode显示文摘 | WU Tai Bor SHY Hsiou Jeng | 2000 | Ceram Int2000，26，： | 1 |
| 15 | The comparison of biological character- istics and multilineage differentiation of bone marrow and adipose derived mesenchymal stem ceils 显示文摘 | Zhu X Shi W Tai W | 2012 | Cell Tissue Res2012，350，2： | 1 |
| 16 | The comparition of biological characteristics and multilineage differentiation of bone marrow and adipose derived Mesenchymal stem cells显示文摘 | Xishan Zhu Wei Shi Weiping Tai Fuquan Liu | 2012 | Cell and Tissue Research2012，，2： | 1 |
| 17 | Overexpression of galectin‐1 is associated with poor prognosis in human hepatocellular carcinoma following resection显示文摘 | Han Wu Pei Chen Rui Liao Yi‐Wei Li Yong Yi Jia‐Xing Wang Tai‐Wei Sun Jian Zhou Ying‐Hong Shi Xin‐Rong Yang Jian‐Jun Jin Yun‐Feng Cheng Jia Fan Shuang‐Jian Qiu | 2012 | Journal of Gastroenterology and Hepatology2012，，8： | 1 |
| 18 | Lack of association between transforming growth factor - β1 gene polymorphisms and mitral valve prolapse in Taiwan Chinese显示文摘 | Hsiang - Tai Chou Yi - Ru Shi Yuan Hsu | 2002 | Journal Heart Valve Dis2002，11，： | 1 |
| 19 | Diabetes abolishes the cardioprotection induced by sevoflurane postconditioning in the rat heart in vivo: roles of glycogen synthase kinase-3β and its upstream pathways 显示文摘 | Tai W Shi E | 2012 | J Surg Res2012，178，1： | 1 |
| 20 | Nanosecond dynamics of the mouse acetylcholinesterase Cys-Cys omega loop 显示文摘 | Shi JX Tai KH Cammon AM | 2003 | J Biol Chem2003，278，30： | 1 |
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