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    题名 作者 年代 出处 被引量
1蛋白酶激活受体2在载脂蛋白E缺陷小鼠的血管炎症和动脉粥样硬化中发挥关键作用显示文摘凝血系统与血管炎症密切相关,尽管其潜在机制仍不清楚。最近的研究结果表明,蛋白酶激活受体(protease-activated receptor,PAR)2——活化因子X(activated factor X,FXa)的主要受体之一——在血管细胞和白细胞中均有表达,这提示PAR-2可能参与炎症性疾病的发病机制。Hara T Phuong PT Fukuda D Yamaguchi K Murata C Nishimoto S Yagi S Kusunose K Yamada H Soeki T Wakatsuki T Imoto I Shimabukuro M Sata M 刘青 叶鹏 2018中华高血压杂志2018,26,6:11
2Transformation:how do nematode sperm become activated and crawl?显示文摘Nematode sperm undergo a drastic physiological change during spermiogenesis(sperm activation).Unlike mammalian flagellated sperm,nematode sperm are amoeboid cells and their motility is driven by the dynamics of a cytoskeleton composed of major sperm protein(MSP)rather than actin found in other crawling cells.This review focuses on sperm from Caenorhabditis elegans and Ascaris suum to address the roles of external and internal factors that trigger sperm activation and power sperm motility.Nematode sperm can be activated in vitro by several factors,including Pronase and ionophores,and in vivo through the TRY-5 and SPE-8 pathways.Moreover,protease and protease inhibitors are crucial regulators of sperm maturation.MSP-based sperm motility involves a coupled process of protrusion and retraction,both of which have been reconstituted in vitro.Sperm motility is mediated by phosphorylation signals,as illustrated by identification of several key components(MPOP,MFPs and MPAK)in Ascaris and the characterization of GSP-3/4 in C.elegans.Xuan Ma Yanmei Zhao Wei Sun Katsuya Shimabukuro Long Miao 2012Protein & Cell2012,3,10:4
3Increased oxidative stress in obesity and its impact on metabolic syndrome显示文摘Furukawa S Fujita T Shimabukuro M 2004JClinlnves2004,114,12:1
4Evaluation of Compositing Algorithms over the Brazilian Amazon Using SPOT-4 VEGETATION Data显示文摘Carreiras J Pereira J Shimabukuro Y 2003International Journal of Remote Sensing2003,24,17:1
5Direct interaction between gingival fibroblasts and lymphoid cells induces inflammatory cytokine mRNA expression in gingival fibroblasts显示文摘Murakami S Hino E Shimabukuro Y 1999J Dent Res1999,78,:1
6Comparison of selection pressures on the HA gene of pandemic (2009) and seasonal human and swine influenza A H1 subtype viruses显示文摘Furuse Y Shimabukuro K Odagiri T 2010Virology2010,405,2:1
7Role of nitric oxide in obesity-induced beta cell disease 显示文摘Shimabukuro M Ohneda M Lee Y 1997J Clinical Iavestlg1997,100,2:1
8Hypoadiponectinemia is closely linked to endothelial dysfunction in human显示文摘Shimabukuro M Higa N Asahi T 2003J Clin Endocrinol Metab2003,88,:1
9Vascular lipotoxicity : endothelial dysfunction via fatty-acid-induced reactive oxygen species over production in obese Zucker diabetic fatty rats 显示文摘Chinen I Shimabukuro M Yamakawa K 2007Endocrinology2007,148,1:1
10A fast technique for unit commitment problem by extended priority list显示文摘Senjyu T Shimabukuro K Uezato K 2003IEEE Trans on Power Systems2003,18,2:1
11Induction of heat shock response:effect on the rat liver with carbon tetrachlorize-induced fibrosis from ischemia-reperfusion injury显示文摘Shimabukuro T Yamamoto Y Kume M 1998World J Surg1998,22,5:1
12Linear Mixing Model Applied to Coarse Spatial Resolution Data from Multispectral Satellite Sensors显示文摘Holben B N Shimabukuro Y E 1993International Journal of Remote Sensing1993,14,11:1
13Peptide inhibitors of angiontensin-converting enzyme in digests of gelatin by bacterial collagenase显示文摘Oshima G Shimabukuro H Nagasawa K 1979Biochimica et Biophysica Acta1979,566,1:1
14Ob-Rb gene transfer to leptin-resistant islets reverses diabetogenic phenotype 显示文摘Wang MY Koyama K Shimabukuro M 1998Proc Natl Acad Sci USA1998,95,:1
15Glutathione conjuga-tion:atrazine detoxication mechanism in com显示文摘Shimabukuro R H Swanson H R Walsh W C 1970Plant Physiology1970,46,1:1
16Airway management with dexmedetomidine for difficult airway 显示文摘Shimabukuro A Satoh K 2007Masui2007,56,6:1
17Increased oxi- dative stress in obesity and its impact on metabolic syndrome 显示文摘Furukawa S Fujita T Shimabukuro M 2004J Clin Invest2004,114,12:1
18Troglitazone lowers islet fat and restores beta cell function of Zucker diabetic fatty rats显示文摘Shimabukuro M Zhou YT Lee Y 1998J Biol Chem1998,273,:1
19Cardioprotective effects of troglitazone in streptozotocin-induced diabetic rats显示文摘Shimabukuro M Higa S Shinzato T 1996Metabolism1996,45,9:1
20Cardiac adiposity and global cardiometabolic risk: new concept and clinical implication显示文摘Shimabukuro M 2009Circ J2009,73,1:1
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