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143篇 您的检索式:作者名="Simon F N"
    题名 作者 年代 出处 被引量
1血浆游离DNA水平增高可作为预测重型颅脑损伤患者死亡率的独立指标(英文)显示文摘Trauma is the leading cause of death under 45 years worldwide and up to 50% of trauma fatalities are due to brain injury.Prediction of outcome is one of the major problems associated with severe TBI and research efforts have focused on the investigation of biomarkers with prognostic value following TBI. Therefore,our aim was to investigate whether cell-free DNA concentrations correlated to short-term primary outcome( survivor or death) and GCS scores following severe TBI. A total of 188 victims of severe TBI were enrolled in this prospective study,outcome variables comprised: survival and neurological assessment using the GCS at ICU discharge. Control blood samples were obtained from 25 healthy volunteers. Peripheral venous blood was collected at admission in the ICU. Plasma DNA was measured using a real-time quantitative PCR assay for the β-globin gene. There was correlation between higher DNA levels and both fatal outcome and lower hospital admission GCS scores. Plasma DNA concentrations at the chosen cut- off point( ≥171,381 kilogenomesequivalents /L) predicted mortality with a specificity of 90% and a sensitivity of 43%. Logistic regression analysis showed that elevated plasma DNA levels were independently associated with death( P < 0. 001). In conclusion,high cell-free DNA concentration was a predictor of short-term mortality following severe TBI.Rodrigues Filho EM1 Simon D Ikuta N Klovan C Dannebrock F de Oliveira CO Regner A 2014中华神经外科疾病研究杂志2014,13,3:6
2查看详情显示文摘Mijatovic T De Nève N Bruyère C Simon G Dewelle J Van Quaquebeke E Van Der A.E Van Vynckt F Lefranc F Kiss R 0,,:1
3Resistin regulates human cho cell invasive behaviour and en dothelial cell angiogenic processes显示文摘Di Simone N Di Nicuolo F Sanguinetti M 2006J Endocrinol2006,189,3:1
4A study of the effect of acetylation and propionylation surface treatments on natural fibres 显示文摘Tserki V Zafeiropoulos N E Simon F 2005Composites Part A: Applied Science and Manufacturing2005,36,8:1
5Error-related psychophysiology and negative affect显示文摘Hajcak G McDonald N Simons R F 2004Brain and Cognition2004,56,:1
6A QTL affecting milk yield and composition maps to bovine chromosome 20: A confirmation 显示文摘Arranz J J Coppieters W Berzi P Cambisano N Grisart B Karim L Marcq F Moreau L Mezer C Riquet J Simon P Vanmanshoven P Wagenaar D and Georges M 1998Animal Genetics1998,29,:1
7Decision framing:Moderating effects of individual differences and cognitive processing显示文摘Simon A F Fagley N S Halleran J G 2004Journal of Behavioral Decision Making2004,,17:1
8A single step process for the simultaneous purification and opening of multiwalled carbon nanotubes显示文摘Raymundo-Pi(n)ero E Cacciaguerra T Simon P Béguin F 0,,1:1
9Resistin regulates human choriocarcinoma cell invasive behaviour and endothelial cell angiogenic processes 显示文摘Di Simone N Di Nicuolo F Sanguinetti M 2006Endocrinol2006,189,3:1
10Deregulation of the platelet-derived growth factor B-chain gene (PDGBF) via its fusion with the collagen gene (COL1A1) in dermatoflbrosarcoma protuberans and giant-cell flbroblastoma显示文摘Simon MP Pedeutour F Sirvent N 1997Nat Genet1997,15,:1
11Hypoglycemic effects of sesquiterpene glycosides and polyhydroxylated triterpenoids of Eriobotrya japonica显示文摘de Tommasi N de Simone F Cirino G 1991Planta Med1991,57,5:1
12Resistin regulates human choriocareinoma cell invasive behaviour and endothelial cell angiogenic processes显示文摘Di Simone N Di Nicuolo F Sanguinetti M 2006J Endocrinol2006,189,69:1
13Low molecular weight heparininduces in vitro trophablast invasiveness :role of matrix metalloproteinases and tissue inhibitors显示文摘Di Simone N DiNicuolo F Sannguinetti M 2007Placenta2007,28,:1
14Constituents of Eriobotrya japonica,a study of their antiviral properties显示文摘de Tommasi N de Simone F Pizza C 1992J Nat Prod1992,55,8:1
15Deregulation of the platelet derived growth factor B-chain gene via fusion with collagen gene COL1 A1 in cell fibmblastoma显示文摘Simon MP Pedeutour F Sirvent N 1997Nat Genet1997,15,1:1
16Resistin regulates human choriocarcinoma cell invasive behaviour and endothelial cell angiogenie processes显示文摘Di Simone N Di Nicuolo F Sanguinetti M 2006J Endocrinol2006,189,3:1
17Bibliography on load management 显示文摘ISAKSEN L MA F SIMONS N 1981IEEE Trans Power App Syst1981,100,5:1
18A highly efficient low temperature modification of the classical ullmann reaction显示文摘Leroux F R Simon R Nicod N 2006Letters in Organic Chemistry2006,10,3:1
19Constitu- ents of Eriobotrya japonica : A study of their antiviral properties显示文摘De TOMMASI N De SIMONE F PIZZA C 1992Journal of Natural Products1992,55,8:1
20Hypoglycemic Effects of Sesquiterpene Glycosides and Polyhydroxylated Triterpenoids of Efio- botrya japonica显示文摘De Tommasi N De Simone F Cirino G 1991Planta medica1991,57,05:1
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