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68篇 您的检索式:作者名="Sir J"
    题名 作者 年代 出处 被引量
1Topotecan in the treatment of rcplased small cell lung cancer patients with poor pcrfommnce status 显示文摘Treat J Huang CH Lane SiR 2004Oncolgist2004,9,:1
2Production of recombinant HIV-1Nef(negativefactor)protein using Pichia pastoris and alow-temperature fed-batch strategy显示文摘Sirén N Weegar J Dahlbacka J 2006Biotechnol Appl Biochem2006,44,3:1
3Epidemic spreading on complex networks with community structure 显示文摘SIR Zhang J P Jin Z 2012Applied Mathematics and Computation2012,219,6:1
4Intestestinal absorption of protein in teleost fish 显示文摘Sir M F Verrier J M 1992Comp Biochem Physiol1992,,103:1
5Randomised comparison of combined step-down prednisolone, methotrexate and sulphasalazine with sulphasalazine alone in early rheumatoid arthritis显示文摘Maarten Boers Arco C Verhoeven Harry M Markusse Mart AFJ van de Laar Rene Westhovens J Christiaan van Denderen Derkjen van Zeben Ben AC Dijkmans Andre J Peeters Piet Jacobs Hans R van den Brink Hubert JA Schouten Désirée MFM van der Heijde Annelies Boonen 1997The Lancet1997,,9074:1
6The preparation of PbO2 coatings on reticulated vitreous carbon for the electro-oxidation of organic pollutants显示文摘Recio F J Herrasti P Sirés I 0,,14:1
7难治性类风湿关节炎的临床特点:一项国际问卷调查研究显示文摘目的尽管按照目前欧洲抗风湿联盟(EULAR)的推荐对类风湿关节炎(rheumatoid arthritis,RA)患者进行治疗,难治性RA患者的临床症状却仍然没有得到完全控制,目前EULAR指南主要关注的是RA的早期治疗和药物治疗。本研究的目的在于分析难治性RA患者的临床特点,以及在患者管理中需要探索然而现有EULAR指南并未涉及的问题。方法对多个国家的风湿科医生进行问卷调查,分析难治性RA的临床特点。问卷包括多选题以及开放性问题,从开放性问题的回答中发现需要进一步阐明的问题以及现有EULAR指南需要增加的内容。结果410名受访者完成了调查问卷,关于难治性RA的特点:50%受访者认为基于28个关节评估的疾病活动评分(disease activity score assessing 28 joints,DAS28)>3.2或存在疾病活动的征象;42%受访者认为疲劳是其特点;48%认为至少两种传统合成改变病情抗风湿药(DMARDs)以及使用至少两种生物制剂或靶向合成DMARDs治疗失败;89%认为糖皮质激素不能减量到5 mg/天或泼尼松不能减量到10 mg/天或同等剂量的其他激素。另外,现有EULAR指南中应增加合并症和关节外表现的干预以及多种药物联合治疗等重要内容。结论目前风湿科医生对难治性RA的定义有很大争议。难治性RA患者的很多重要问题目前EULAR指南中均没有涉及。Nadia MT Roodenrijs Maria J H de Hair Marlies C van der Goes Johannes WG Jacobs Paco MJ Welsing Désirée van der Heijde Daniel Aletaha Maxime Dougados Kimme L Hyrich Iain B McInnes Ulf Mueller-Ladner Ladislav Senolt Zoltan Szekanecz Jacob Mvan Laar Nagy Gyorgy 黄艳荣(译) 张卓莉(审校) 2019英国医学杂志中文版2019,22,2:1
8Unappreciable Myocardial Bridge Causing Anterior myocardial Infarction and Postinfarction Angina显示文摘Diaz-Widmann J Cox Sir Roongsritong C 2003South Med J2003,96,4:1
9Autophagy by hepatitis B virus and for hepatitis B virus显示文摘Sir D Ann D K Ou J H 2010Autophagy2010,6,4:1
10The preparation of PbO2 coatings on reticulated vitreous carbon for the dectro-oxidation of organic pollutants显示文摘Recio F J Herrasti P Sirés I 0,,:1
11Chemoradiothrea py after surgery compared with surgery alone for adenocarcino ma of the stomach or gastroesophageal junction显示文摘MacDonald JS Smalley SIR Benedetti J 2001N Engl J Med2001,345,10:1
12Basalin sulin therapy in type 2 diabetes: 28-week comparison of insulin glargine (HOE901) and NPH insulin 显示文摘Rosenstock J Schwartz Sir Clark CM Jr 2001Diabetes Care2001,24,4:1
13Production of recombinant HIV-1 Nef (negativefactor) protein using Pichia pastoris and a low-temperature fed-batch strategy显示文摘Sirén N Weegar J Dahlbacka J 0,,3:1
14On the injective chromatic number of graphs显示文摘Hahn G Kratochvil J Sirán J 2002Discrete Mathematics2002,256,:1
15Microsomal prostaglandin E synthase-1 is a major terminal synthase that is selectively up-regula- ted during cyclooxygenase-2-dependent prostaglandin E2 production in the rat adjuvant induced arthritis model显示文摘Claveau D Sir inyanM Guay J 2003J Immunol2003,170,:1
16Olanzapine-induced weight gain in the rat: role of 5-HT2C and histamine H1 re- ceptors 显示文摘Kirk Sir Glazebrook J Grayson B 2009Psychopharmacol2009,207,1:1
17The mechanism of smouldering in cigarette 显示文摘EGERTOM SIR A GUGAN K WEINERG F J 1963Combust Flame1963,7,:1
18Arsenic trioxide cause selective necrosis in solid murine tumors by vascular shutdown显示文摘Young Sir Stephen LB Robert J 1999Cancer Res1999,59,24:1
19Ontheinjectivechromaticnumberofgraphs显示文摘HahnG KratochvílJ SiráJ etal 2002DiscreteMath2002,256,12:1
20Hepatic fibrogenesis显示文摘Guo J Friedman Sir 2007Semin laver Dis2007,27,4:1
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