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| 1 | Hybrid multi-chip assembly of optical communication engines by in situ 3D nanolithography显示文摘Three-dimensional(3D)nano-printing of freeform optical waveguides,also referred to as photonic wire bonding,allows for efficient coupling between photonic chips and can greatly simplify optical system assembly.As a key advantage,the shape and the trajectory of photonic wire bonds can be adapted to the mode-field profiles and the positions of the chips,thereby offering an attractive alternative to conventional optical assembly techniques that rely on technically complex and costly high-precision alignment.However,while the fundamental advantages of the photonic wire bonding concept have been shown in proof-of-concept experiments,it has so far been unclear whether the technique can also be leveraged for practically relevant use cases with stringent reproducibility and reliability requirements.In this paper,we demonstrate optical communication engines that rely on photonic wire bonding for connecting arrays of silicon photonic modulators to InP lasers and single-mode fibres.In a first experiment,we show an eight-channel transmitter offering an aggregate line rate of 448 Gbit/s by low-complexity intensity modulation.A second experiment is dedicated to a four-channel coherent transmitter,operating at a net data rate of 732.7 Gbit/s-a record for coherent silicon photonic transmitters with co-packaged lasers.Using dedicated test chips,we further demonstrate automated mass production of photonic wire bonds with insertion losses of(0.7±0.15)dB,and we show their resilience in environmental-stability tests and at high optical power.These results might form the basis for simplified assembly of advanced photonic multi-chip systems that combine the distinct advantages of different integration platforms. | Matthias Blaicher Muhammad Rodlin Billah Juned Kemal Tobias Hoose Pablo Marin-Palomo Andreas Hofmann Yasar Kutuvantavida Clemens Kieninger Philipp-Immanuel Dietrich Matthias Lauermann Stefan Wolf Ute Troppenz Martin Moehrle Florian Merget Sebastian Skacel Jeremy Witzens Sebastian Randel Wolfgang Freude Christian Koos | 2020 | Light(Science & Applications)2020，9，1： | 4 |
| 2 | The expression of fascin: an actin-bunding motility protein, correlates with hormone receptor-negative breast cancer and a more aggressive clinical course显示文摘 | Yoder BJ Tso E Skacel M | 2005 | Clin Cancer Res2005，11，1： | 1 |
| 3 | Multitarget fluorescence in situ hybridization assay detects transitional cell carcinoma in the majority of patients with bladder cancer and atypical or nega- tive urine cytology 显示文摘 | Skacel M Fahmy M Brainard JA etM | 2003 | JUrol2003，169，6： | 1 |
| 4 | Roles of Fascin in human carcinoma motility and signaling: prospects for a novel biomarker? 显示文摘 | Hashimoto Y Skacel M Adams J C | 2005 | Int J Biochem Cell Biol2005，37，9： | 1 |
| 5 | Roles of Fascin in human cacinoma motility and signaling : prospects for a novel biomarker 显示文摘 | Hashimoto Y Skacel M Adams JC | 2005 | Int J Bio- chem Cell Biol2005，37，9： | 1 |
| 6 | Chromosomal alterations in low - and high - grade squamous intraepithelial lesions ( LSIL and HSIL) of the uterine cervix detected by muhieolor fluorescence in situ hybridization(FISH) 显示文摘 | Fahmy M Skacel M Brainard J et 01 | 2002 | Acta Cytol2002，46，4： | 1 |
| 7 | The expression of fascin,an action-bunding motility protein,correlates with hormone receptor-negative breast cancer and a more aggressive Clinical course显示文摘 | Yoder BJ Tso E Skacel M | 2005 | Clin Cancer Res2005，11，1： | 1 |
| 8 | Prognostic significance of fascin expression in advanced colorectal cancer: an immunohistochemical study of colorectal adenomas and adenocarcinomas 显示文摘 | Hashimoto Y Skacel M Lavery IC | 2006 | BMC Cancer2006，6，4： | 1 |
| 9 | The expression of fascin,an action-bunding motility protein,correlates with hormone receptor-negative breast cancer and a more aggressive Clinical course显示文摘 | Yoder BJ Tso E Skacel M | 2005 | Clin Cancer Res2005，11，1： | 1 |
| 10 | Muhitarget fluorescence in situ hybridization assay dectects transitional cell carcinoma in the majority of patients with bladder cancer and atypical or negativurine cytology显示文摘 | Skacel M Fahmy M Brainard JA | 2003 | J Urel2003，169，6： | 1 |
| 11 | Epithelioid sarcoma: an immunohistochemical analysis evaluating the utility of cytokeratin 5/6 in distinguishing superficial epithelioid sarcoma from spindled squamous cell carcinoma 显示文摘 | Lin L Skacel M Sigel JE | 2003 | J Cutan Pathol2003，30，2： | 1 |
| 12 | Multitarget fluorescence in situ hybridization assay detects transitional cell carcinoma in the majority of patients with bladder cancer and atypical or negative urine cytology显示文摘 | Skacel M Fahmy M Brainard JA | 2003 | J Urol2003，169，6： | 1 |
| 13 | Multitarget fluorescence in situ hybridization assay detects transitional cell carcinoma in the majority of patients with bladder cancer and atypical or negative urine cytology显示文摘 | Skacel M Fahmy M Brainard JA | 2003 | J Urol2003，169，6： | 1 |
| 14 | Prognostic significance of fascin expression in advanced colorectal cancer:an immunohistochemical study of colorectal adenomas and adenocarcinomas显示文摘 | Hashimoto Y Skacel M Lavery IC | 2006 | BMC Cancer2006，6，10： | 1 |
| 15 | The diagnosis of leprosy among patient with symptoms of peripheral ncuropathy without cutaneous lesions:a follow-up study显示文摘 | Skacel M Antunes SL Rodrigues MM | 2000 | Arq Neuropsiquiatr2000，58，： | 1 |
| 16 | Reflex UroVys- ion testing of bladder cancer surveillance patients with equivo- cal or negative urine cytology: a prospective study with focus on the natural history of anticipatory positive findings 显示文摘 | Yoder B J Skacel M Hedgepeth R | 2007 | Am J Clin Pathol2007，127，2： | 1 |
| 17 | Association of loss of epithelial syndecan-1 with stage and local metastasis of colorectal adenocarcinomas: an study of clinically annotated tmnors显示文摘 | Hashimoto Y Skacel M Adams JC | 2008 | BMC Cancer2008，8，： | 1 |
| 18 | Roles of fascin in human carcinoma motility and signaling:prospects for a novel biomarker?显示文摘 | HASHIMOTO Y SKACEL M ADAMS J C | 2005 | Int J Biochem Cell Biol2005，37，9： | 1 |
| 19 | Multitarget fluorescence in situ hybridization assay detects transitional cell carcinoma in the majority of patients with bladder cancer and atypical or negative urine cytology显示文摘 | Skacel M Fahmy M Brainard JA | 2003 | J Urol2003，169，： | 1 |
| 20 | Roles of Fascin in humancacinoma motility and signaling: prospects for a novel biomarker显示文摘 | Hashimoto Y Skacel M Adams JC | 2005 | Int J Biochem Cell Biol2005，37，9： | 1 |
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