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| 1 | Effectiveness of probiotic therapy for the prevention of relapse in patients with inactive ulcerative colitis显示文摘AIM: to evaluate the effectiveness of probiotic therapy for suppressing relapse in patients with inactive ulcerative colitis(UC).METHODS: Bio-Three tablets, each containing 2 mg of lactomin(Streptococcus faecalis T-110), 10 mg of Clostridium butyricum TO-A, and 10 mg of Bacillus mesentericus TO-A, were used as probiotic therapy.Sixty outpatients with UC in remission were randomly assigned to receive 9 Bio-Three tablets/day(BioThree group) or 9 placebo tablets/day(placebo group)for 12 mo in addition to their ongoing medications.Clinical symptoms were evaluated monthly or on the exacerbation of symptoms or need for additional medication. Fecal samples were collected to analyze bacterial DNA at baseline and 3-mo intervals. Terminal restriction fragment length polymorphism and cluster analyses were done to examine bacterial components of the fecal microflora.RESULTS: Forty-six patients, 23 in each group,completed the study, and 14 were excluded. The relapse rates in the Bio-Three and placebo groups were respectively 0.0% vs 17.4% at 3 mo(P = 0.036), 8.7%vs 26.1% at 6 mo(P = 0.119), and 21.7% vs 34.8%(P = 0.326) at 9 mo. At 12 mo, the remission rate was 69.5% in the Bio-Three group and 56.6% in the placebo group(P = 0.248). On cluster analysis of fecal flora, 7 patients belonged to cluster Ⅰ, 32 to cluster Ⅱ,and 7 to cluster Ⅲ.CONCLUSION: Probiotics may be effective formaintaining clinical remission in patients with quiescent UC, especially those who belong to cluster Ⅰ on fecal bacterial analysis. | Yasushi Yoshimatsu Akihiro Yamada Ryuichi Furukawa Koji Sono Aisaku Osamura Kentaro Nakamura Hiroshi Aoki Yukiko Tsuda Nobuo Hosoe Nobuo Takada Yasuo Suzuki | 2015 | World Journal of Gastroenterology2015，21，19： | 21 |
| 2 | Implications of fine water mist environment on the post-detonation processes of a PE4 explosive charge in a semi-confined blast chamber显示文摘The effects of a fine water mist environment in a semi-confined blast chamber on the chemical and thermodynamic processes following detonation of a 20 g PE4 explosive charge have been investigated.The effects were quantified by the analysis of pressure profiles recorded where several parameters including arrival time of the shock at the sensors, peak overpressures, specific impulse of the positive phase, period of the negative phase and the specific impulse of the multiple reflections were quantified.The effect of the fine water mist on the arrival time, peak pressures and the specific impulse of the positive phase agrees with previous findings in literature. In this paper, the focus is on the implications of the fine water mist on the negative phase and the impulse of multiple pressure reflections. The period of the negative phase was found to have increased by 40% and with higher negative peak pressure in the mist condition compared to the atmospheric condition. The activities of the multiple pressure reflections were found to have decreased considerably, both in number and in amplitude leading to lower impulses(by about 60%) for the water mist conditions. | Zetu Jiba Tleyane Jonas Sono Frederik Johannes Mostert | 2018 | Defence Technology(防务技术)2018，14，5： | 3 |
| 3 | Detection of myeloperoxidase gene expression by in situ hybridization in a case of granulocytic sarcoma associated with AML-M0显示文摘 | Miyazato H Sono H Naiki Y | 2001 | Leukemia2001，15，11： | 1 |
| 4 | Revision of diagnostic guidelines for Kawasaki disease显示文摘 | Ayusawa M Sono T Uemura S | 2005 | Pediatr Int2005，47，2： | 1 |
| 5 | Eremophilane-type sesquiterpenes from fresh rhizomes of Petasites japonicus显示文摘 | Tori M Kawahara M Sono M | 1998 | Phytochemistry1998，47，： | 1 |
| 6 | Immunohistochemical localization of indoIeamine 2,3-dioxygenase in the argyrophilic cells of rabbit duodenum and thyroid gland 显示文摘 | Watanabe Y Yoshida R Sono M | 1981 | J Histochem Cytochem1981，29，： | 1 |
| 7 | Improvement of Emission Characteristics Uniformity of Carbon Nanotube Field Emission Display By Surface Treatment显示文摘 | Shiroishi T Hosono A Sono A | 2006 | Journal of Vacuum Science & Technology B2006，24，2： | 1 |
| 8 | Regulation of mitochondrial biogenesis by lipoprotein lipase in muscle of insulin-resistant offspring of parents with type 2 diabetes显示文摘 | Morino K Petersen KF Sono S | 2012 | Diabetes2012，61，4： | 1 |
| 9 | Nine new clerodane diterpenoids from rhizomes of Solidago altissima显示文摘 | Tori M Katto A Sono M | 1999 | Phytochemistry1999，52，3： | 1 |
| 10 | 1-Methyl-DL-tryptophan, beta-(3-benzo- furanyl)-DL-alanine (the oxygen analog of tryptophan) , and be- ta- -DL-alanine ( the sulfur analog of trypto- phan) are competitive inhibitors for indoleamine 2,3-dioxygenase 显示文摘 | CADY SG SONO M | 1991 | Arch Biochem Biophys1991，291，2： | 1 |
| 11 | Detection of myeloperoxidase gene expression by in situ hybridization in a case of granulocytic sarcoma associated with AML-M0 显示文摘 | Miyazato H Sono H Naiki Y | 2001 | Leukemia2001，15，11： | 1 |
| 12 | Liquid-liquid extraction of manganese(Ⅱ), copper(Ⅱ) and zinc(Ⅱ) with acyclic and maerocyelic Schiff bases containing bisohenol A subunits显示文摘 | ABE S FUJII K SONO T | 1994 | Analytica Chimica Acta1994，293，： | 1 |
| 13 | Heat deteriora- tion of phospholipids I: decomposition of soybean lecithin and formation of new products by heating显示文摘 | SONO R BAN N SAKAMOTO S | 2001 | J Oleo Sci2001，50，11： | 1 |
| 14 | In vitro evaluation of plant-derived agents to preserve dentin collagen 显示文摘 | Hiraishi N Sono R Sofiqul I | 2013 | Dent Ma- ter2013，29，10： | 1 |
| 15 | Mass transfer coefficient for suspending particles in agitated vessel and bubble columns显示文摘 | Yamaguchi N Adachi T | 1974 | J Chem Eng Japan1974，，7： | 1 |
| 16 | 1-Methyl-DL-tryptophan, beta-(3- benzofuranyl)-DL-alanine (the oxygen analog of tryptophan), and beta--DL-alanine (the sulfur analog of tryptophan) are competitive inhibitors for indoleamine 2, 3-dioxygenase 显示文摘 | Cady SG Sono M | 1991 | Arch Biochem Biophys1991，291，2： | 1 |
| 17 | 1 Methyl-DL tryptophan, beta-(3 benzofuranyl ) DE alanine ( the oxygen analog of tryptophan) , and beta DL-alanine ( the sulfur analog of tryptophan) are competitive inhibitors for indoleamine 2, 3 dioxygenase 显示文摘 | CADY SG SONO M | 1991 | Arch Biochelr 13iopk) s1991，291，2： | 1 |
| 18 | The effect of active immuno2neutralization of inhibin in ewes during the early luteal phase of the oestrous cycle on ovarian hormone secretion and follicular development显示文摘 | Compbell B K Gordon B M T sonos C G | 1995 | J Endocrino 11995，145，47： | 1 |
| 19 | Periodic DNA methylation in maize nucleosomes and demethylation by environmental stress显示文摘 | Steward N Ito M Yamaguchi Y Koizumi N Sono H | 2002 | J Biol Chem2002，277，37： | 1 |
| 20 | , Ono K: Desilification of kraft liquors high in sili- ca显示文摘 | sono Z | 1968 | Chemical Abstract1968，42，1： | 1 |
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