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| 1 | Beneficial effect of sulphate-bicarbonate-calcium water on gallstone risk and weight control显示文摘AIM:To investigate the effect of drinking sulphate-bicarbonate-calcium thermal water (TW) on risk factors for atherosclerosis and cholesterol gallstone disease.METHODS:Postmenopausal women with functional dy-spepsia and/or constipation underwent a 12 d cycle of thermal (n=20) or tap (n=20) water controlled drinking.Gallbladder fasting volume at ultrasound,blood vitamin E,oxysterols (7-β-hydroxycholesterol and 7-ketocholesterol),bile acid (BA),triglycerides,total/low density lipoprotein and high density lipoprotein cholesterol were measured at baseline and at the end of the study.Food consumption,stool frequency and body weight were recorded daily.RESULTS:Blood lipids,oxysterols and vitamin E were not affected by either thermal or tap water consumption.Fasting gallbladder volume was significantly (P<0.005) smaller at the end of the study than at baseline in the TW (15.7±1.1 mL vs 20.1±1.7 mL) but not in the tap water group (19.0±1.4 mL vs 19.4±1.5 mL).Total serum BA concentration was significantly (P<0.05) higher at the end of the study than at baseline in the TW (5.83±1.24μmol vs 4.25±1.00μmol) but not in the tap water group (3.41±0.46μmol vs 2.91±0.56μmol).The increased BA concentration after TW consumption was mainly accounted for by glycochenodeoxycholic acid.The number of pasta (P<0.001),meat (P<0.001) and vegetable (P<0.005) portions consumed during the study and of bowel movements per day (P<0.05) were significantly higher in the TW than in the tap water group.Body weight did not change at the end of the study as compared to baseline in both groups.CONCLUSION:Sulphate-bicarbonate-calcium water consumption has a positive effect on lithogenic risk and intestinal transit and allows maintenance of a stable body weight despite a high food intake. | Stefano Ginanni Corradini Flaminia Ferri Michela Mordenti Luigi Iuliano Maria Siciliano Maria Antonella Burza Bruno Sordi Barbara Caciotti Maria Pacini Edoardo Poli Adriano De Santis Aldo Roda Carolina Colliva Patrizia Simoni Adolfo Francesco Attili | 2012 | World Journal of Gastroenterology2012，18，9： | 3 |
| 2 | Titanium-coated polypropylene mesh as innovative bioactive material in conservatives mastectomies and pre-pectoral breast reconstruction显示文摘Breast reconstruction is rapidly evolving,thanks to the growing acceptance of synthetic meshes as innovative biomaterials.276 patients undergoing mastectomy(total of 328 mastectomies)were analyzed in a retrospective observational study to evaluate the pre-pectoral immediate breast reconstruction(IBR)using an implant wrapped with Titanium-Coated Polypropylene Mesh(TCPM)vs.patients treated with tissue expander(TE),equally placed pre-pectorally(and wrapped with the same TCPM in 74.3%of the control group’breasts).163 patients,of the study group(SG),underwent mastectomy and pre-pectoral IBR with implant wrapped with TCPM,in a one-step surgery,called direct-to-implant technique(DTI),while 113 patients control group(CG)underwent mastectomy and TE.DTI technique has been performed in 192 breasts of the SG while TE procedure in 136 breasts of the CG.The BREAST-Q questionnaire has been provided before the treatment and 2 years later.Baker scale has been used to evaluate capsular contracture.Oncologic,surgical,and aesthetic outcomes along with BREAST-Q scores were analyzed.Additionally,a histologic evaluation was conducted in 11 capsules’samples randomly chosen(6 derived from SG patients and 5 derived from CG).Complications were recorded in 43 cases(29SG-14CG):8 skin-nipple necrosis(5SG-3CG),8 wound dehiscence(6SG-2CG),3 hematomas(1SG-2CG),and 24 infections(8SG-16CG).Grade IV capsular contracture was detected in 9 breasts(1SG-8CG),whereas 254 breasts were grade I(110SG-144CG),33(10SG-23CG)grade II,and 32(4SG-28CG)grade III.Implant wrinkling was detected in 18 cases(10SG-8CG)after 30 months.The local tumor recurrence rate was 5.8%.Three recurrences were on the nipple-areola complex(1.9%).SG patients showed significantly higher rates in the BREAST-Q overall Satisfaction with Outcome(74.1),overall Satisfaction with Breasts(69.1),Psychosocial Well-being(81.9),and Sexual Well-being(63.1),versus CG’s patients(p<0.05).Histological analysis showed a process of normal tissue repair with a complete mesh integration and normal healing.Conservative mastectomies with pre-pectoral IBR assisted by TCPM proved themselves oncologically safe,biologically integrated into native tissues,and highly accepted in terms of quality of life guaranteeing a more natural and aesthetic breast appearance.Core tip:This retrospective observational study provided clinical and histological outcomes of the pre-pectoral IBR using an implant wrapped with TCPM vs.patients treated with TE,equally placed pre-pectorally.The efficacy of IBR using an implant wrapped with TCPM was confirmed by the cosmetic results obtained and by a rate of side effects comparable to TE.All the histological analyses performed confirmed the TCPM mesh complete integration with the physiological aspects of healing:The Collagen 1 and 3 expressions did not differ,between TCPM and NO TCPM samples to confirm a process of healing overlapping to perfect device incorporation and normal healing. | Pietro Gentile Marco Bernini Lorenzo Orzalesi Silvia Sordi Icro Meattini Francesca Lessi Ashutosh Kothari Claudio Calabrese | 2021 | Bioactive Materials2021，6，12： | 2 |
| 3 | Al−Mg−Si合金在低温下的流变行为和断裂显示文摘研究AA6061合金的拉伸和断裂行为,为该合金在低温范围内的拉伸和断裂行为提供定量数据。在298 K、173 K和77 K下对铝合金进行固溶处理,然后在应变速率为0.1~0.0001 s^(−1)条件下进行拉伸试验。结果表明,77 K时Portevin−Le Chatelier(PLC)效应和动态应变时效(DSA)被抑制。相反,298 K时,观察到PLC效应的特征,即明显的锯齿状流变。77 K固溶处理后样品的拉伸性能与173 K和298 K处理的样品拉伸性能相比,强度、伸长率、韧性模量、应变硬化指数和应变速率敏感性同时提高,这与低温下动态回复速率的降低有关。与之相对应,断口形貌结果显示,77 K处理的样品韧窝尺寸减小,而韧窝覆盖的面积增加。173 K和77 K处理的样品中DSA被抑制,其实验结果与Johnson−Cook模型模拟结果吻合较好。 | Danielle Cristina Camilo MAGALHAES Andrea Madeira KLIAUGA Vitor Luiz SORDI | 2021 | Transactions of Nonferrous Metals Society of China2021，31，3： | 2 |
| 4 | Relative efficiencies of the maximum parsimony and disentance matrix methods in obtaining the correct phylogenetic tree显示文摘 | SORDIS J NEI M | 1988 | Molecular Biology and evolution1988，5，： | 1 |
| 5 | Early potassium channel blockade improves sepsis-induced organ damage and cardiovascular dysfunction显示文摘 | Sordi R Fernandes D Heckert BT | 2011 | Br J Pharmaco12011，163，6： | 1 |
| 6 | The presence,type and role of N-acyl homoserine lactone quorum sensing infiuorescent Pseudomonas originally isolated from rice rhizospheres are unpredictable显示文摘 | STEINDLER L BERTANI I DE SORDI L | 2008 | FEMS Microbiol Lett2008，288，1： | 1 |
| 7 | Bone mar row mesenchymal stem cells Express a restricted set of func- tionally active chemokine receptors capable of promoting mi- gration to pancreatic islets显示文摘 | SORDI V MALOSIO M L MARCHESI F | 2005 | Blood2005，106，2： | 1 |
| 8 | Bone marrow mesenchy- real stem cells express a restricted set of functionally active chemokine receptors capable of promoting migration to pan- creaticislets显示文摘 | Sordi V Malosio ML Marchesi F | 2005 | Blood2005，106，2： | 1 |
| 9 | A preclinical evaluation of pemetrexed and irinotocan combination as second-line chemotherapy in pancreatic cancer显示文摘 | Mercalli A Sordi V Formicola R | 2007 | BrJ Cancer2007，96，5： | 1 |
| 10 | Bone marrow mesenchymal stem cells express a restricted set of functionally active chemokine receptors capable of promoting migration to pancreatic islets 显示文摘 | SORDI V MALOSIO M L MARCHESI F | 2005 | Blood2005，106，2： | 1 |
| 11 | Late, but not early, inhibition of soluble guanylate cyclase decreases mortality in a rat sepsis model显示文摘 | Fernandes D Sordi R Pacheco LK | 2009 | J Pharmacol Exp Ther2009，328，3： | 1 |
| 12 | Early potassium channelblockade improves sepsis-induced organ damage and cardiovasculardysfunction 显示文摘 | Sordi R Fernandes D He<-kert BT | 2011 | Br J Pharmacol2011，163，6： | 1 |
| 13 | A preclinical evaluation of pemetrexed and irinotecan combination as second-line chemotherapy in pancreatic cancer 显示文摘 | Mercalli A Sordi V Formicola R | | Br J Cancer0，96，9： | 1 |
| 14 | mesenchymal stem cell homing capacity显示文摘 | Sordi V | 2009 | Transplantation2009，87，9： | 1 |
| 15 | Mesenchymal cells appearing in pancreatic tissue culture are bone marrow-derived stem cells with the capacity to improve transplanted islet function显示文摘 | Sordi V Melzi R Mercalli A | 2010 | Stem Cells2010，28，1： | 1 |
| 16 | Mesenchymal stem cell homing capacity 显示文摘 | Sordi V | 2009 | Transplantation2009，87，9： | 1 |
| 17 | Bone marrow mesenchyma stem cells express a restricted set of functionally active chemokine receptors capable of promoting migration to pancreatic islets显示文摘 | SORDI V MALOSIO M L MARCHESI F | 2005 | Blood2005，106，2： | 1 |
| 18 | Bone marrow mesencbymal stem cells express a restricted set of func- tionally active chemokine receptors capable of promoting migration to pancreatic islets 显示文摘 | Sordi V Malosio M L Marchesi F | 2005 | Blood2005，106，2： | 1 |
| 19 | Aromatic compounds produced by Periconia atropur purea ,an endophytic fungus associated with Xylopia aromatica显示文摘 | Teles H L Sordi R Silva G H Castro-Gamboa I Bolzani V S Pfen ing L H | 2006 | Phytochemistry2006，67，： | 1 |
| 20 | Bone marrow mesenchymal stem cells express a restricted set of functionally active chemokine receptors capable of promoting migration to pancreatic islets 显示文摘 | Sordi V Malosio ML Marchesi F | 2005 | Blood2005，106，2： | 1 |
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