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| 1 | 酞咪哌啶酮对多发性骨髓瘤细胞系血管新生抑制作用的研究显示文摘目的 研究多发性骨髓瘤 (MM)细胞系培养上清液对人骨髓来源的内皮细胞系(HBMEC)的增殖、迁移、血管新生的促进作用及酞咪哌啶酮对其抑制作用。方法 用MM细胞系 (IM9、XG1、U2 6 6和MOLP 5 )培养上清液培养HBMEC ,检测其对HBMEC的增殖、迁移作用。在纤维蛋白胶及基质胶 (matrigel)中观察此上清液对血管新生的影响 ,并研究酞咪哌啶酮对这些作用的抑制。用酶联免疫吸附实验 (ELISA)测定此上清液中血管内皮生长因子 (VEGF)含量。结果 MM培养上清液明显促进HBMEC的增殖及迁移。在纤维蛋白胶及基质胶 (matrigel)中 ,促进微血管的生长。这些作用均可被酞咪哌啶酮抑制。所有这些作用与MM细胞系产生的VEGF无相关性。结论 MM细胞系通过分泌VEGF或其他某些细胞因子促进HBMEC的增殖、迁移及微血管形成 ;酞咪哌啶酮可抑制这些作用 。 | 陈文明 朱嘉芷 F Mirshahi J Soria M Mirshahi C Soria | 2002 | 中华血液学杂志2002，23，10： | 5 |
| 2 | Antifeedant effects and chemical composition of essential oils from different populations of Lavandula luisieri L.显示文摘 | Azucena González-Coloma Darío Martín-Benito Nagla Mohamed M a Concepción García-Vallejo Ana Cristina Soria | 2006 | Biochemical Systematics and Ecology2006，，8： | 2 |
| 3 | Regulation of mitochondrial function and endoplasmic reticulum stress by nitric oxide in pluripotent stem cells显示文摘Mitochondrial dysfunction and endoplasmic reticulum stress(ERS) are global processes that are interrelated and regulated by several stress factors. Nitric oxide(NO) is a multifunctional biomolecule with many varieties of physiological and pathological functions, such as the regulation of cytochrome c inhibition and activation of the immune response, ERS and DNA damage; these actions are dose-dependent. It has been reported that in embryonic stem cells, NO has a dual role, controlling differentiation, survival and pluripotency, but the molecular mechanisms by which it modulates these functions are not yet known. Low levels of NO maintain pluripotency and induce mitochondrial biogenesis. It is well established that NO disrupts the mitochondrial respiratory chain and causes changes in mitochondrial Ca^(2+) flux that induce ERS. Thus, at high concentrations, NO becomes a potential differentiation agent due to the relationship between ERS and the unfolded protein response in many differentiated cell lines. Nevertheless, many studies have demonstratedthe need for physiological levels of NO for a proper ERS response. In this review, we stress the importance of the relationships between NO levels, ERS and mitochondrial dysfunction that control stem cell fate as a new approach to possible cell therapy strategies. | Estefania Caballano-Infantes José Terron-Bautista Amparo Beltrán-Povea Gladys M Cahuana Bernat Soria Hajji Nabil Francisco J Bedoya Juan R Tejedo | 2017 | World Journal of Stem Cells2017，9，2： | 2 |
| 4 | Study of photodegradation of the pefticide ethiofencarb in aqueous and non - aqueous media, by gas chromatograghy - mass spectrometry 显示文摘 | J Sanze - Asensio M Plaza - Medina M T Martinez - Soria M Perez -Clavijo | 1999 | Journal of Chromatograghy A1999，84，： | 2 |
| 5 | Regulation of fibrinogen biosynthesis by cytokines, conse- quences on the vascular risk 显示文摘 | VASSE M PAYSANT J SORIA J COLLET JP VANNIER JP SO- RIA C | 1996 | Haemostasis1996，26，： | 1 |
| 6 | Val66Met BDNFGenotypes in melancholic depression: effects on brain struc-ture and treatment outcome显示文摘 | Cardoner N Soria V Gratacos M | 2013 | Depress Anxiety2013，30，3： | 1 |
| 7 | Development of high power VRLA batteries using novel materials and processes 显示文摘 | Soria M L Valenciano J Ojeda A | 2003 | Journal of power sources2003，116，1： | 1 |
| 8 | Preparation and characterization of nibium oxide for the catalytic aldol condensation of acetone 显示文摘 | PAULIS M MARTIN M SORIA D B | 1999 | Applied Catalysis A:General1999，180，12： | 1 |
| 9 | Radio and X--ray Properties of Relativistic Beaming Models for U1- traluminous X--Ray Sources显示文摘 | FREELAND M KUNCIC Z SORIA R | 2006 | MNRAS2006，372，： | 1 |
| 10 | Metal hydride electrodes and Ni/MH batteries for automotive high power applications显示文摘 | SORIA M L CHACON J HEMANDEZ J C | 2001 | J Power Sources2001，102，12： | 1 |
| 11 | Architecture analysis of a river flood-dominated delta during an overall sea-level rise (early Pliocene, SE Spain) 显示文摘 | GARCfA-GARCA F CORBI H SORIA J M | 2011 | Sedimentary Geology2011，237，12： | 1 |
| 12 | Inflammatory mediators inbreast cancer: coordinated expression of TNF a & IL-1 /3 withCCL2 & CCL5 and effects on epithelial-to-mesenchymal transition显示文摘 | Soria G Ofri-Shahak M Haas I | 2011 | BMC Cancer2011，11，： | 1 |
| 13 | Effects of isolated obesity on systolic and diastolic left ventricular function显示文摘 | Pascual M Pascul DA Soria F | 2003 | Heart2003，89，： | 1 |
| 14 | Soft-sediment deformation structures induced by earthquakes(seismites)in Pliocene lacustrine deposits(Guadix-Baza Basin,Central Betic Cordillera)显示文摘 | Alfaro P Moretti M Soria J M | 1997 | Ecological Geologicae Helvetiae1997，90，： | 1 |
| 15 | Detection of undegraded fibrin and tumor necrosis factor-alpha in venous leg ulcers显示文摘 | Claudy AL Mirshahim M Soria C | 1991 | J Am Acad Dermatol1991，25，4： | 1 |
| 16 | 查看详情显示文摘 | Querini C A Ulla M A Requejo F Soria J Sedran U A Miro E E | | 0，，： | 1 |
| 17 | The organization of near-wall turbulence: a comparison between boundary layer SPIV data and channel flow DNS data显示文摘 | Herpin S Stanislas M Soria J | 2010 | Journal of Turbulence2010，11，47： | 1 |
| 18 | Expression of elastase and fibrin in venous leg ulcer biopsies: a pilot study of pentoxifylline versus placebo显示文摘 | Mirshahi S Soria J Mirshahi M | 1995 | J Cardiovasc Pharmacol1995，25，2： | 1 |
| 19 | IEPR study of CO and O2 interaction with supported Au catalysts 显示文摘 | Okumura M CoronadoJ M Soria J | 2001 | Journal of Catalysis2001，203，： | 1 |
| 20 | Straw- berry production in mild climates of the world: A review of current cultivar use 显示文摘 | L6pez-Aranda J M Soria C Santos B M | 2011 | International Journal of Fruit Science2011，11，3： | 1 |
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