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| 1 | Cyclosporine versus tacrolimus in patients with HCV infection after liver transplantation:Effects on virus replication and recurrent hepatitis显示文摘瞄准:决定 calcineurin 禁止者, cyclosporine 和 tacrolimus 的效果,在丙肝上,在病人的周期性的丙肝的病毒(HCV ) 复制和活动张贴肝移植。方法:在我们的中心为在 1999 和 2003 之间的联系 HCV 的肝肝硬化收到了肝移植的 107 个病人的一个队的数据回顾地被分析。浆液 HCV-RNA 的水平和周期性的肝炎的活动在作为主要抑制免疫力的代理人和没在移植以后在开始的 12 瞬间以内导致胆汁的复杂并发症的不那样类似的抑制免疫力的政体收到了 cyclosporine 或 tacrolimus 的 47 个病人之间被比较。结果:HCV-RNA 在移植以后在 3 瞬间以内增加了,但是 cyclosporine 组和 tacrolimus 组之间的差别是不足道的(在 12 瞬间的 P=0.49 ) 。另外,由浆液 transaminases 决定了的周期性的肝炎并且门发炎和纤维变性的组织学的分级没在 12 瞬间(P=0.34 ) 以后显示出有效差量。结论:一个主要抑制免疫力的代理人不在肝移植以后在感染 HCV 的病人影响周期性的肝炎的正式就职或严厉的 Cyclosporine 或 tacrolimus。 | Philip Hilgard Alisan Kahraman Nils Lehmann Cornelia Seltmann Susanne Beckebaum R Stefan Ross Hideo A Baba Massimo Malago Christoph E Broelsch Guido Gerken | 2006 | World Journal of Gastroenterology2006，12，5： | 235 |
| 2 | 酒精摄入、心脏生物标志物和心房颤动风险与不良结局显示文摘酒精摄入和新发心房颤动相关性证据不一,尤其是在低剂量下。该研究评估欧洲队列在整个饮酒范围内酒精摄入、生物标志物和新发心房颤动的关系。方法和结果:在一个以社区为基础的汇集队列中,研究者随访107845人,以评估酒精摄入(酒精种类和饮酒方式)与新发心房颤动的关系。研究者收集经典心血管病危险因素和新发心力衰竭的信息,并检测生物标记物氨基末端脑钠肽前体和高敏肌钙蛋白I。 | 陈嘉睿(译) 练桂丽((审校) Csengeri D Sprünker NA Di Castelnuovo A Niiranen T Vishram-Nielsen JK Costanzo S S derberg S Jensen SM Vartiainen E Donati MB Magnussen C Camen S Gianfagna F L chen ML Kee F Kontto J Mathiesen EB Koenig W Stefan B de Gaetano G J rgensen T Kuulasmaa K Zeller T Salomaa V Iacoviello L Schnabel RB | 2021 | 中华高血压杂志2021，29，2： | 9 |
| 3 | Ultrasound-assessed non-culprit and culprit coronary vessels differ by age and gender显示文摘AIM: To investigate age-and gender-related differences in non-culprit versus culprit coronary vessels assessed with virtual histology intravascular ultrasound (VH-IVUS). METHODS: In 390 patients referred for coronary angiography to a single center (Luzerner Kantonsspital, Switzerland) between May 2007 and January 2011, 691 proximal vessel segments in left anterior descending, circumflex and/or right coronary arteries were imaged by VH-IVUS. Plaque burden and plaque composition(fibrous, fibro-fatty, necrotic core and dense calcium volumes) were analyzed in 3 age tertiles, according to gender and separated for vessels containing non-culprit or culprit lesions. To classify as vessel containing a culprit lesion, the patient had to present with an acute coronary syndrome, and the VH-IVUS had to be performed in a vessel segment containing the culprit lesion according to conventional coronary angiography. RESULTS: In non-culprit vessels the plaque burden increased significantly with aging (in men from 37% ± 12% in the lowest to 46% ± 10% in the highest age tertile, P < 0.001; in women from 30% ± 9% to 40% ± 11%, P < 0.001); men had higher plaque burden than women at any age (P < 0.001 for each of the 3 age tertiles). In culprit vessels of the lowest age tertile, plaque burden was significantly higher than that in non- culprit vessels (in men 48% ± 6%, P < 0.001 as compared to non-culprit vessels; in women 44% ± 18%, P = 0.004 as compared to non-culprit vessels). Plaque burden of culprit vessels did not significantly change during aging (plaque burden in men of the highest age tertile 51% ± 9%, P = 0.523 as compared to lowest age tertile; in women of the highest age tertile 49% ± 8%, P = 0.449 as compared to lowest age tertile). In men, plaque morphology of culprit vessels became increasingly rupture-prone during aging (increasing percentages of necrotic core and dense calcium), whereas plaque morphology in non-culprit vessels was less rupture-prone and remained constant during aging. In women, necrotic core in non-culprit vessels was very low at young age, but increased during aging resulting in a plaque morphology that was very similar to men. Plaque morphology in culprit vessels of young women and men was similar. CONCLUSION: This study provides evidence that age-and gender-related differences in plaque burden and plaque composition significantly depend on whether the vessel contained a non-culprit or culprit lesion. | Andreas W Schoenenberger Nadja Urbanek Stefan Toggweiler Andreas E Stuck Thérèse J Resink Paul Erne | 2013 | World Journal of Cardiology2013，5，3： | 7 |
| 4 | A sensitivity study of the WRF model in offshore wind modeling over the Baltic Sea显示文摘Accurate wind modeling is important for wind resources assessment and wind power forecasting. To improve the WRF model configuration for the offshore wind modeling over the Baltic Sea, this study performed a sensitivity study of the WRF model to multiple model configurations, including domain setup,grid resolution, sea surface temperature, land surface data, and atmosphere-wave coupling. The simulated offshore wind was evaluated against LiDAR observations under different wind directions, atmospheric stabilities, and sea status. Generally, the simulated wind profiles matched observations, despite systematic underestimations. Strengthening the forcing from the reanalysis data through reducing the number of nested domains played the largest role in improving wind modeling. Atmosphere-wave coupling further improved the simulated wind, especially under the growing and mature sea conditions.Increasing the vertical resolution, and updating the sea surface temperature and the land surface information only had a slight impact, mainly visible during very stable conditions. Increasing the horizontal resolution also only had a slight impact, most visible during unstable conditions. Our study can help to improve the wind resources assessment and wind power forecasting over the Baltic Sea. | Huidong Li Björn Claremar Lichuan Wu Christoffer Hallgren Heiner Körnich Stefan Ivanell Erik Sahlée | 2021 | Geoscience Frontiers2021，12，6： | 2 |
| 5 | A Short Amino-Terminal Part of Arabidopsis Phytochrome A Induces Constitutive Photomorphogenic Response显示文摘Phytochrome A (phyA ) 是在 Arabidopsis thaliana 察觉到的 far-red 光的主导的光敏电阻器。phyA 在发信号的变白的幼苗,和导致光的 phyA 的细胞质在高水平积累被一个复杂规章的网络调停。这包括光 -- 并且进在 vivo 的原子核的本国的 phyA 的 FHY1/FHL 蛋白质依赖者 translocation。phyA (PHYA406 ) 的短 N 终端碎片对 phenocopy 足够,这也被显示出在 vitro 的这个高度调整的细胞的过程。为了测试这 N 终端的生物活动,在 planta phyA 碎裂,我们生产了表示 PHYA406YFP 的转基因的 phyA-201 植物(黄荧光灯蛋白质) DD, PHYA406YFPDDNLS (原子本地化信号) ,和 PHYA406YFPDDNES (原子出口信号) 熔化蛋白质。这里,我们报导 PHYA406YFPDD 被进口进原子核,而 PHYA406YFPDDNLS 和 PHYA406YFPDDNES 显示期望的组成的本地化模式,这进程部分是轻依赖者的。我们的结果证明这些截断的 phyA 蛋白质是轻马厩的,当局部性时,他们在他们的原子核,和两个都不触发组成的象 photomorphogenic 一样回答导致合适的 phyA 发信号。我们证明在 vitro 并且在 vivo PHYA406, Pfr 和 Pr 绑 COP1, photomorphogenesis 的一个一般抑压者,并且在原子身体与它共同本地化。因此,我们断定在 planta,截断的 PHYA406 蛋白质以一种光无关的方式在原子核使 COP1 失去活性。 | Andra's Viczia'n E'va Ada'm Iris Wolf Ja'nos Bindics Stefan Kircher Marc Heijde Roman Ulm Eberhard Scha'fer Ferenc Nagy | 2012 | Molecular Plant2012，5，3： | 2 |
| 6 | Magnetic response of metamaterialst 100 terahertz显示文摘 | Stefan Linden L Christian E Martin W | 2004 | Science2004，306，5700： | 1 |
| 7 | Recent advances in chlorophyll biosynthesis and breakdown in higher plants显示文摘 | ULRICH E BERNHARD G STEFAN H | 2004 | Plant Molecular Biology2004，56，1： | 1 |
| 8 | Cataract surgery and postoperative endophthalmitis显示文摘 | Stefan C Anghel GH Tebeanu E | | 0，，03： | 1 |
| 9 | Evaluation of sheet metal formability by tensile tests显示文摘 | Stefan H Bertil E Thilderkvist P | 2004 | Journal of Materials Processing Technology2004，145，1： | 1 |
| 10 | Control strategy for NOx-emission reduction with SCR 显示文摘 | Dieter H E Seher Michael Reichelt Stefan Wickert | 2003 | SAE Paper2003，，1： | 1 |
| 11 | Scale-free topology of e-mail networks显示文摘 | Lutz I M Stefan B | 2002 | Phys Rev E2002，66，03： | 1 |
| 12 | Structural and optical characterization of porous anodic aluminum oxide显示文摘 | AUREIAAN C GaLca STEFAN KOOIJ E HERBERT Wormeester | 2003 | J Appl Phys2003，94，7： | 1 |
| 13 | Can economic in-centives encourage actual reductions in pesticide use andenvironmental spillovers? 显示文摘 | Skevas T Stefanou S E Lansink A 0 | 2012 | Agricultural Economics2012，43，3： | 1 |
| 14 | Progressive cognitive decline in epilepsy:an indication of ongoing plasticity显示文摘 | Stefan H Pauli E | 2002 | Prog-Brain-Res2002，，135： | 1 |
| 15 | The use of Bacillus subtilis for screening fusaric acid production by Fusarium spp显示文摘 | Antonia S Stefan E Da T | 2009 | Czech Journal of Food Sciences2009，27，3： | 1 |
| 16 | Porcine Torque teno virus:Determination of viral genomie loads by geno-group-specic multiplex rt-PCR detection of frequent mul- tiple infections with geno groups 1 or 2, and establish- ment of viral full-length sequences 显示文摘 | Andreas G Stefan P Wiebke S E | 2010 | Vet Microbiol2010，143，24： | 1 |
| 17 | Identification of a Vacuolar Sucrose Transporter in Barley and Arabidopsis Meso- phyll cells by a Tonoplast Proteomic Approach显示文摘 | ANNE E STEFAN M SILVIA S | 2006 | American So- ciety of Plant Biologists2006，141，1： | 1 |
| 18 | New vaccines for tuberculosis 显示文摘 | STEFAN H E KAUFMANN G H PAUL-HENRI L | 2010 | Lancet2010，375，9731： | 1 |
| 19 | ^1H-MRS profile in MRI positive-versus MRI negative patients with temporal lobe epilepsy显示文摘 | Doelken MT Stefan H Pauli E | 2008 | Seizure2008，17，6： | 1 |
| 20 | MicroR- NAs: a newly described class of encoded molecules that play a role in health and disease 显示文摘 | Felekkis K Touvana E Stefanou C H | 2010 | Hippokratia2010，14，4： | 1 |
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