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| 1 | High-resolution microendoscopy for esophageal cancer screening in China: A cost-effectiveness analysis显示文摘AIM:To study the cost-effectiveness of high-resolution microendoscopy(HRME)in an esophageal squamous cell carcinoma(ESCC)screening program in China.METHODS:A decision analytic Markov model of ESCC was developed.Separate model analyses were conducted for cohorts consisting of an averagerisk population or a high-risk population in China.Hypothetical 50-year-old individuals were followed until age 80 or death.We compared three different strategies for both cohorts:(1)no screening;(2)standard endoscopic screening with Lugol’s iodine staining;and(3)endoscopic screening with Lugol’s iodine staining and an HRME.Model parameters were estimated from the literature as well as from GLOBOCAN,the Cancer Incidence and Mortality Worldwide cancer database.Health states in the model included non-neoplasia,mild dysplasia,moderate dysplasia,high-grade dysplasia,intramucosal carcinoma,operable cancer,inoperable cancer,and death.Separate ESCC incidence transition rates were generated for the average-risk and high-risk populations.Costs in Chinese currency were converted to international dollars(I$)and were adjusted to 2012dollars using the Consumer Price Index.RESULTS:The main outcome measurements for this study were quality-adjusted life years(QALYs)and incremental cost-effectiveness ratio(ICER).For the average-risk population,the HRME screening strategy produced 0.043 more QALYs than the no screening strategy at an additional cost of I$646,resulting in an ICER of I$11808 per QALY gained.Standard endoscopic screening was weakly dominated.Among the high-risk population,when the HRME screening strategy was compared with the standard screening strategy,the ICER was I$8173 per QALY.For both the high-risk and average-risk screening populations,the HRME screening strategy appeared to be the most cost-effective strategy,producing ICERs below the willingness-topay threshold,I$23500 per QALY.One-way sensitivity analysis showed that,for the average-risk population,higher specificity of Lugol’s iodine(>40%)and lower specificity of HRME(<70%)could make Lugol’s iodine screening cost-effective.For the high-risk population,the results of the model were not substantially affected by varying the follow-up rate after Lugol’s iodine screening,Lugol’s iodine test characteristics(sensitivity and specificity),or HRME specificity.CONCLUSION:The incorporation of HRME into an ESCC screening program could be cost-effective in China.Larger studies of HRME performance are needed to confirm these findings. | Chin Hur Sung Eun Choi Chung Yin Kong Gui-Qi Wang Hong Xu Alexandros D Polydorides Li-Yan Xue Katherine E Perzan Angela C Tramontano Rebecca R Richards-Kortum Sharmila Anandasabapathy | 2015 | World Journal of Gastroenterology2015，21，18： | 8 |
| 2 | Neoadjuvant and adjuvant therapy for resectable hepatocellular carcinoma: review of the randomised clinical trials显示文摘 | Jonathan D Schwartz Myron Schwartz John Mandeli Max Sung | 2002 | Lancet Oncology2002，，10： | 3 |
| 3 | 高级别子宫内膜间质肉瘤的分子改变及免疫治疗策略显示文摘高级别子宫内膜间质肉瘤(HG-ESS)为子宫内膜间质肉瘤(EST)的一种组织学亚型,治疗原则以手术为主,内分泌治疗、放疗、化疗为辅,总体预后不良。效果不确切,新的治疗策略如免疫治疗成为当下研究的热点。最新研究表明,HG-ESS可获益于免疫治疗。 | 王星语(编译) 张师前(编译) Kim Y Kim D Sung WJ | 2022 | 中华医学杂志2022，102，20： | 2 |
| 4 | Non-planar dynamic modeling for the optical disk drive spindles equipped with an automatic balancer显示文摘 | Chao P C Huang Y D Sung C K | 2003 | Mechanism and Machine Theory2003，38，： | 1 |
| 5 | Effects of channel geometrical con- figuration and shoulder width on PEMFC performance at high cur- rent density显示文摘 | AHMED D H SUNG H J | 2006 | Journal of Power Sources2006，162，： | 1 |
| 6 | Protection of mouse photoreceptors by survival factors in retinal degeneration 显示文摘 | Lavail MM Yasumura D Matthes MT Lau-Villacorta C Unoki K Sung CH | 1998 | Invest Ophthalmol Vis Sci1998，39，3： | 1 |
| 7 | Protection of mouse photoreceptors by survival factors in retinal degenerations 显示文摘 | LaVail MM Yasumura D Matthes MT Lau-Villacorta C Unoki K Sung CH Steinberg RH | 1998 | Invest Ophthalmol Vis Sci1998，39，3： | 1 |
| 8 | New briaranes fromthe octocorals Briareum excavatum (Briareidae) andJunceella fragilis ( Ellisellidae) 显示文摘 | Sung P J Lin M R Su Y D | 2008 | Tetrahedron2008，64，11： | 1 |
| 9 | Update on coxsack- ievirus B3 myocarditis 显示文摘 | Fairweather D Stafford KA Sung YK | 2012 | Curr Opin Rheumatol2012，24，： | 1 |
| 10 | Monitoring of selected veterinary antibiotics in environmental compartments near a composting facility in Gangwon Province,Korea显示文摘 | Ok Y S Kim S C Kim K R Lee S S Moon D H Lim K J Sung J K Hur S O Yang J E | | 0，，： | 1 |
| 11 | Enhancement of optical re- mote sensing images by subband-decomposed multi- scale Retinex with hybrid intensity transfer Function 显示文摘 | Jae H J Sung D K Jong B | 2011 | IEEE Geoscience and Remote Sensing Letters2011，8，5： | 1 |
| 12 | Satellite Selection Scheme for Reducing Handover Attempts in LEO Satellite Communication Systems显示文摘 | KWON Y YOUNG Y J SUNG D | 1998 | International Journal of Satellite Communications1998，16，4： | 1 |
| 13 | Effect of alloying elements on the strength and casting characteristics of high strength Al-Zn-Mg-Cu alloys 显示文摘 | KIM K T KIM J M SUNG K D | 2005 | Materials Science Forum2005，，： | 1 |
| 14 | Characteristics of technology transfer in business venture:the case of Daejeon, Korea 显示文摘 | SUNG T K GIBSON D V KANG B | 2003 | Technological Forecasting & Social Change2003，，： | 1 |
| 15 | Catalytic Decomposition of Hydrogen Peroxide on Iron Oxide: Kinetics, Mechanism, and Implications显示文摘 | Shu- Sung Lin Mirat D Gurol | 1999 | Environ Sci Technol1999，32，14： | 1 |
| 16 | Experimental study on transmission efficiency of a rubber V-belt CVT 显示文摘 | Chen T F Lee D W Sung C K | 1998 | Mechanism and Machine Theory1998，33，4： | 1 |
| 17 | A coupled structural-acoustic finite element model for vehicle Interior noise analysis 显示文摘 | Sung S H Nefske D J | 1984 | Transactions of the ASME Journal of Vibration Acoustics Stress and Reliability in Design1984，106，： | 1 |
| 18 | Serum alpha-fetoprotein in the early stage of human hepat-cellular carcinoma显示文摘 | Che D S Sung J L Shen J C | 1984 | Gastroenterology1984，86，1： | 1 |
| 19 | Novel valsartan-loaded solid dispersion with enhanced bioavailability and no crystalline changes 显示文摘 | YAN Y D SUNG J H KIM K K | 2012 | lnt J Pharm2012，422，12： | 1 |
| 20 | Probabilistic Assessment of Slope Stability That Considers the Spatial Variability of Soil Properties 显示文摘 | Sung Eun Cho Ph D | 2010 | Journal of the fourth eivil/geotechnicai engineering geotecbnical2010，，： | 1 |
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