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1良性阵发性位置性眩晕:诊断标准--Bárány学会前庭疾病分类委员会共识显示文摘本文是由Bárány学会前庭疾病分类委员会制定的关于良性阵发性位置性眩晕(BPPV)的可操作性诊断指南。该分类反映了对BPPV临床表现和病理机制的最新认识,并且包含了BPPV已知明确的和新兴的类型。张祎 刘博 Von Brevern M Bercholon P Brandt T 2017听力学及言语疾病杂志2017,25,5:24
2FOLFIRI联合西妥昔单抗或贝伐珠单抗治疗晚期结直肠癌:随机临床试验FIRE-3的最终生存及符合方案分析显示文摘背景:在FIRE-3研究中,与贝伐珠单抗+FOLFIRI相比,西妥昔单抗+FOLFIRI可提高KRAS野生型转移性结直肠癌(mCRC)的总生存率,但是未发现相应的无进展生存获益。本研究目的在于分析RAS野生型结直肠癌接受一线FOLFIRI治疗的可评价疗效患者中,与贝伐珠单抗相比,西妥昔单抗是否可改善治疗反应和生存情况,同时分析原发肿瘤部位对预后的影响。方法:意向治疗人群包括593例KRAS第2外显子野生型mCRC患者。进一步检测确认400名患者为全RAS野生型肠癌,其中352名(88%)患者接受了至少3个周期的治疗和至少1次基线后的影像检查以评估疗效,并纳入符合方案的患者(西妥昔单抗组169名,贝伐珠单抗组183名)。何婉 HEINEMANN V VON WEIKERSTHAL L F DECKER T 2021结直肠肛门外科2021,27,1:11
3前庭症状的分类:迈向前庭疾患的国际分类显示文摘1引言巴拉尼协会(Barany Society)前庭疾患分类委员会于2006年在乌普萨拉召开的巴拉尼协会会议上正式成立,其任务是促进建立一种可应用的前庭疾患的分类。对症状和疾病的定义是在临床和研究中实现专业交流的最基本前提。然而。冯智英 杨晓岚 沈沸 季伟华 蒋仙国 李颖 邹静 李焰生 Bisdorff A Von Brevernb M Lempertc T Newman-Tokerd DE 2012神经病学与神经康复学杂志2012,9,3:7
4Adenosquamous carcinoma of the pancreas: Molecular characterization of 23 patients along with a literature review显示文摘Adenosquamous carcinoma of the pancreas(ASCP)is a rare entity. Like adenocarcinoma of the pancreas,overall survival is poor. Characteristics of ASCP include central tumor necrosis, along with osteoclasts and hypercalcemia. Various theories exist as to why this histological subtype exists, as normal pancreas tissue has no benign squamous epithelium. Due to the rarity of this disease, limited molecular analysis has been performed, and those reports indicate unique molecular features of ASCP. In this paper, we characterize 23 patients diagnosed with ASCP through molecular profiling using immunohistochemistry staining, fluorescent in situ hybridization, chromogenic in situ hybridization, and gene sequencing, Additionally, we provide a comprehensive literature review of what is known to date of ASCP.Molecular characterization revealed overexpression in MRP1(80%), MGMT(79%), TOP2A(75), RRM1(42%),TOPO1(42%), PTEN(45%), CMET(40%), and C-KIT(10%) among others. One hundred percent of samples tested were positive for KRAS mutations. This analysis shows heretofore unsuspected leads to be considered for treatments of this rare type of exocrine pancreas cancer. Molecular profiling may be appropriate to provide maximum information regarding the patient's tumor. Further work should be pursued to better characterize this disease.Erkut Borazanci Sherri Z Millis Ron Korn Haiyong Han Clifford J Whatcott Zoran Gatalica Michael T Barrett Derek Cridebring Daniel D Von Hoff 2015World Journal of Gastrointestinal Oncology2015,7,9:6
5Epidemiology of vestibular vertigo: A neurotologic survey of the general population显示文摘H K. Neuhauser M von Brevern A Radtke F Lezius M Feldmann T Ziese T Lempert 2005Neurology2005,,6:2
6Long-term antidepressant treatment with Moclobemide for aphasia in acute stroke patients:a randomised,double-blind,placebo-controlled study显示文摘Laska AC von Arbin M Kahan T el al 2005Cerebrovasc Dis2005,19,2:1
7Identification of molecular markers linked to Rdrl,a gene conferring resistance to blackspot in roses显示文摘Von Malek B Weber W E Debener T 2000Theor Appl Genet2000,101,:1
8Effect of dietary keto acid on intermediary metabolism of nutrients in Atlantic salmon (Salmo salar) during 17 betha-estradiol-induced vitellogenin synthesis 显示文摘Olin T Junjvid H Von der Decken A 1992Anita Sei1992,42,:1
9Retinal artery occlusion following intravitreal anti-VEGF therapy显示文摘von Hanno T Kinge B Fossen K 2010Acta Ophthalmol2010,88,2:1
10Public transport networks: empirical analysis and modeling显示文摘C von Ferber Holovatch T 2009Eur Phys J2009,68,:1
11Comfort and diacomfort of dental trauma splints-a comparison of a new device(TTS) with tree commonly used splintiny techniques显示文摘Filippi A Von Aex T Lussi A 2003Dent-traumatol2003,18,5:1
12Solar chimney turbine characteristics 显示文摘VON B T W GANNON A J 2004Solar Energy2004,,76:1
13Paclitaxel-induced apoptosis in BJAB cells proceeds via a death receptor-independent,caspases-3 /-8-driven mitochondrial amplification loop显示文摘von Haefen C Wieder T Essmann F 2003Oncogene2003,22,15:1
14DWI in transient global amnesia and TIA:proposal for an ischaemic origin of TGA显示文摘WINBECK K ETGEN T VON EINSIEDEL HG 2005Neurosurg Psychiatry2005,76,:1
15Toward automatic reconstruction of a highly resolved tree of life 显示文摘CICCARELLI F D DOERKS T VON MERING C 2006Science2006,311,:1
16Corneal architecture of femtosecond laser and microkeratome flaps imaged by anterior segment optical coherence tomography显示文摘von Jagow B Kohnen T 0,,01:1
17The standardization of terminology of lower urinary tract function in children and adolescents:report from the Standardisation Committee of the International Children's Continence Society显示文摘Nevéus T von Gontard A Hoebeke P 0,,:1
18Characterization of the inhibition of hepatitis C virus entry by in vitro-generated and patient-derived oxidized low-density lipoprotein显示文摘Westhaus S Bankwitz D Ernst S Rohrmann K Wappler I AgnéC Luchtefeld M Schieffer B Sarrazin C Manns M P Pietschmann T Ciesek S von Hahn T 2013Hepatology2013,57,5:1
19Diffusion tensor imaging of skeletal muscle-correlation of fractional anisotropy to muscle power 显示文摘Scheel M Prokscha T von Roth P 2013Rofo2013,185,:1
20Compressibility effects in aerodynamics 显示文摘Von Krmn T 2012J Aeronaut Sci2012,8,9:1
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