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| 1 | Prognostic factors in patients with advanced cholangiocarcinoma: Role of surgery, chemotherapy and body mass index显示文摘AIM: To study the factors that may affect survival of cholangiocarcinoma in Lebanon. METHODS: A retrospective review of the medical records of 55 patients diagnosed with cholangio- carcinoma at the American University of Beirut between 1990 and 2005 was conducted. Univariate and multivariate analyses were performed to determine the impact of surgery, chemotherapy, body mass index, bilirubin level and other factors on survival. RESULTS: The median survival of all patients was 8.57 mo (0.03-105.2). Univariate analysis showed that low bilirubin level (< 10 mg/dL), radical surgery and chemotherapy administration were significantly associated with better survival (P = 0.012, 0.038 and 0.038, respectively). In subgroup analysis on patients who had no surgery, chemotherapy administration prolonged median survival significantly (17.0 mo vs 3.5 mo, P = 0.001). Multivariate analysis identifiedonly low bilirubin level < 10 mg/dL and chemotherapy administration as independent predictors associated with better survival (P < 0.05). CONCLUSION: Our data show that palliative and postoperative chemotherapy as well as a bilirubin level < 10 mg/dL are independent predictors of a significant increase in survival in patients with cholangiocarcinoma. | Mirna H Farhat Ali I Shamseddine Ayman N Tawil Ghina Berjawi Charif Sidani Wael Shamseddeen Kassem A Barada | 2008 | World Journal of Gastroenterology2008，14，20： | 9 |
| 2 | Effect of mucin production on survival in colorectal cancer:A case-control study显示文摘AIM: To investigate the impact of mucin production on prognosis in colorectal cancer, in terms of overall survival (OS) and time to disease progression (TTP) in patients with mucinous compared to those with non-mucinous colorectal cancer (NMCRC), matched for age, gender, and tumor stage.METHODS: Thirty five patients with mucinous colorectal cancer (MCRC) were matched for age, gender, and tumor stage with 35 controls having NMCRC. OS and TTP were compared among 4 groups divided according to mucin content: group A (50%-75% mucin), group B (75%-100% mucin), group C or controls (< 50% mucin). Group D consisted of all patients with tumors having < 75% mucin (controls and groups A together).RESULTS: Median survival in MCRC and NMCRC groups was 46.2 and 112.9 mo, respectively (P = 0.26). OS in groups A and B was 70.1 and 32.8 mo (P = 0.46), and in groups B and D was 32.8 and 70.1 mo, respectively (P = 0.143). TTP in MCRC and NMCRC was 50.17 and 44.77 mo, respectively (P = 0.795). TTP in groups A, B, and D was 70.1, 24.8, and 65.5 mo, respectively. Twenty-eight percent of patients with MCRC had poorly differentiated adenocarcinoma versus 8.6% in NMCRC patients (P = 0.028).CONCLUSION: MCRC is associated with a non-significant decrease in median survival and TTP, particularlywhen mucin content is > 75% of tumor volume. However, it tends to be more poorly differentiated. A larger study matching for stage and grade is needed. | Mirna H Farhat Kassem A Barada Ayman N Tawil Doha M Itani Hassan A Hatoum Ali I Shamseddine | 2008 | World Journal of Gastroenterology2008，14，45： | 6 |
| 3 | Alkali fusion of zir- con sand 显示文摘 | Barawy K A E Tawil S Z E and Francis A A | 2000 | Mineral Processing and Extractive Metallurgy2000，109，1： | 1 |
| 4 | Tracheal schwan- noma: a misleading entity显示文摘 | Hamdan A 1 Moukarbel R V Tawil A | 2010 | Middle East J Anesthesiol2010，20，4： | 1 |
| 5 | Tracheal schwanno- ma: a misleading entity显示文摘 | Fiamdan AL Moukarbel R~ Tawil A | 2010 | Middle East J Anaesthesiol2010，20，4： | 1 |
| 6 | Peripherally inserted central venous catheters in newborn infants:malpositioning and spontaneous correction of catheter tips显示文摘 | Tawil KA Eldemerdash A Hathlol KA | | 0，，01： | 1 |
| 7 | Gestational and postnatal maturation of duodenal motor responses to intragastric feeding显示文摘 | Tawil A Berseth CL | 1996 | J Pediatr1996，129，3： | 1 |
| 8 | Wilms' tumor in the adult-report of a case and review of the literature显示文摘 | Tawil A Cox JN Roth AD | 1999 | Pathol Res Pract1999，195，2： | 1 |
| 9 | suppresses proliferation of DU145 human prostate cells显示文摘 | TAJ M M TAWIL R J Mxil a Myc antagonist ENGSTROM L D | 2001 | Prostate2001，47，： | 1 |
| 10 | peripherally inserted central catheters in newborn infants:malpositioning and spontaneous correction of catheter tips显示文摘 | Tawil KA Eldemerdash A Hathlol KA | | 0，，01： | 1 |
| 11 | Non- Hodgkin's lymphoma presenting as a urethral caruncle 显示文摘 | Khatib R'A Khalfl A M Tawil A N | 1993 | Gynecol Oneol1993，50，3： | 1 |
| 12 | Alkali reductive roasting of ilmenite ore显示文摘 | TAWIL S Z MORSI I M YEHIA A FRANCIS A A | 1996 | Canadian Metallurgical Quarterly1996，35，1： | 1 |
| 13 | Junctional Adhesion Mole- cules(JAMs) are differentially expressed in fibroblasts and co- localize with ZO-1 to adherens-like junctions 显示文摘 | Morris AP Tawil A Berkova Z | 2006 | Cell Commun Adhes2006，13，4： | 1 |
| 14 | Periosteal osteoblastoma of the calvaria mimicking a meningioma显示文摘 | Tawil A Comair Y Nasser H | 2008 | Pathol Res Pratt2008，204，6： | 1 |
| 15 | Significance of CEA and VEGF asdiagnostic markers of colorectal cancer in lebanese patients显示文摘 | Dbouk HA Tawil A Nasr F | 2007 | Open Clin Cancer J2007，1，： | 1 |
| 16 | Extraction of a large self-amputated colonic lipoma: a case report显示文摘 | Sidani S M Tawil A N Sidani M S | 2008 | Int J Surg2008，6，5： | 1 |
| 17 | Hexural reliability of reinforced concrete bridge girders strengthened with carbon fiber - reinforced polymer laminates 显示文摘 | OKEIL A M EL - TAWIL S SHAHAWY M | | Journal of Bridge Engineering0，7，5： | 1 |
| 18 | Specific ce-llular immune response and cytokine patterns in patients coinfected with hepatitis C virus and Schistosoma mansoni显示文摘 | Kamal SM Bianchi L Al Tawil A | 2001 | J Infect Dis2001，184，8： | 1 |
| 19 | Osteotome Sinus Floor Elevation without Bone Grafts-A 3-Year Retrospective Study with Astra Tech Implants显示文摘 | Robert Fermerg(a)rd Tawil G Mawla M | | 0，，05： | 1 |
| 20 | Antimicrobial re- sistance in Libya: 1970-2011 显示文摘 | Ghenghesh KS Rahouma A Tawil K | 2013 | Libyan J Med2013，27，8： | 1 |
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