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| 1 | Management of femoral neck fractures in the young patient: A critical analysis review显示文摘Femoral neck fractures account for nearly half of all hip fractures with the vast majority occurring in elderly patients after simple falls.Currently there may be sufficient evidence to support the routine use of hip replacement surgery for low demand elderly patients in all but non-displaced and valgus impacted femoral neck fractures.However for the physiologically young patients,preservation of the natural hip anatomy and mechanics is a priority in management because of their high functional demands.The biomechanical challenges of femoral neck fixation and the vulnerability of the femoral head blood supply lead to a high incidence of non-union and osteonecrosis of the femoral head after internal fixation of displaced femoral neck fractures.Anatomic reduction and stable internal fixation are essentials in achieving the goals of treatment in this young patient population.Furthermore,other management variables such as surgical timing,the role of capsulotomy and the choice of implant for fixation remaincontroversial.This review will focus both on the demographics and injury profile of the young patient with femoral neck fractures and the current evidence behind the surgical management of these injuries as well as their major secondary complications. | Thierry Pauyo Justin Drager Anthony Albers Edward J Harvey | 2014 | World Journal of Orthopedics2014，5，3： | 70 |
| 2 | A longitudinal study of SARS-CoV-2-infected patients reveals a high correlation between neutralizing antibodies and COVID-19 severity显示文摘Understanding the immune responses elicited by SARS-CoV-2 infection is critical in terms of protection against reinfection and,thus,for public health policy and vaccine development for COVID-19.In this study,using either live SARS-CoV-2 particles or retroviruses pseudotyped with the SARS-CoV-2 S viral surface protein(Spike),we studied the neutralizing antibody(nAb)response in serum samples from a cohort of 140 SARS-CoV-2 qPCR-confirmed infections,including patients with mild symptoms and also more severe forms,including those that required intensive care.We show that nAb titers correlated strongly with disease severity and with anti-spike IgG levels.Indeed,patients from intensive care units exhibited high nAb titers;conversely,patients with milder disease symptoms had heterogeneous nAb titers,and asymptomatic or exclusive outpatient-care patients had no or low nAbs.We found that nAb activity in SARS-CoV-2-infected patients displayed a relatively rapid decline after recovery compared to individuals infected with other coronaviruses.Moreover,we found an absence of cross-neutralization between endemic coronaviruses and SARS-CoV-2,indicating that previous infection by human coronaviruses may not generate protective nAbs against SARS-CoV-2.Finally,we found that the D614G mutation in the spike protein,which has recently been identified as the current major variant in Europe,does not allow neutralization escape.Altogether,our results contribute to our understanding of the immune correlates of SARS-CoV-2-induced disease,and rapid evaluation of the role of the humoral response in the pathogenesis of SARS-CoV-2 is warranted. | Vincent Legros Solène Denolly Manon Vogrig Bertrand Boson Eglantine Siret Josselin Rigaill Sylvie Pillet Florence Grattard Sylvie Gonzalo Paul Verhoeven Omran Allatif Philippe Berthelot Carole Pélissier Guillaume Thiery Elisabeth Botelho-Nevers Guillaume Millet Jérôme Morel Stéphane Paul Thierry Walzer François-Loïc Cosset Thomas Bourlet Bruno Pozzetto | 2021 | Cellular & Molecular Immunology2021，18，2： | 3 |
| 3 | Comparison between the SAPIEN S3 and the SAPIEN XT transcatheter heart valves:A single-center experience显示文摘AIM To investigate the clinical outcomes of transcatheter aortic valve implantation(TAVI) with the SAPIEN 3 transcatheter heart valve(S3-THV) vs the SAPIEN XT valve(XT-THV).METHODS We retrospectively analyzed 507 patients that underwent TAVI with the XT-THV and 283 patients that received the S3-THV at our institution between March 2010 and December 2015.RESULTS Thirty-day mortality(3.5% vs 8.7%:OR=0.44,P=0.21) and 1-year mortality(25.7% vs 20.1%,P=0.55) were similar in the S3-THV and the XT-THV groups.The rates of both major vascular complication and paravalvular regurgitation(PVR)>1 were almost 4 times lower in the S3-THV group than the XT-THV group(major vascular complication: 2.8% vs 9.9%,P<0.0001:PVR>1: 2.4% vs 9.7%,P<0.0001).However,the rate of new pacemaker implantation was almost twice as high in the S3-THV group(17.3% vs 9.8%,P=0.03).In the S3 group,independent predictors of new permanent pacemaker were pre-procedural RBBB(OR=4.9:P=0.001),pre-procedural PR duration(OR=1.14,P=0.05) and device lack of coaxiality(OR=1.13:P=0.05) during deployment.CONCLUSION The S3-THV is associated to lower rates of major vascular complications and PVR but higher rates of new pacemaker compared to the XT-THV.Sub-optimal visualization of the S3-THV in relation to the aortic valvular complex during deployment is a predictor of new permanent pacemaker. | Fadi J Sawaya Marco Spaziano Thierry Lefèvre Andrew Roy Phillippe Garot Thomas Hovasse Antoinette Neylon Hakim Benamer Mauro Romano Thierry Unterseeh Marie-Claude Morice Bernard Chevalier | 2016 | World Journal of Cardiology2016，8，12： | 2 |
| 4 | Strategic issues in product recovery management显示文摘 | Thierry M Salomon M Van Nunen J | 1995 | California Management Review1995，37，2： | 1 |
| 5 | Strategic issues in product recovery management显示文摘 | Thierry M Salomon M Van Nunen J A | 1995 | Califomia Management Review1995，37，2： | 1 |
| 6 | Terahertz Pulsed Imaging in Vivo: Measurements andProcessing Methods 显示文摘 | Parrott Edward P J Sy Stanley M Y Blu Thierry | 2011 | Journal of Biomedical Optics(S1083-3668)2011，16，10： | 1 |
| 7 | Corrosion resistance for biomaterial applications of Ti02 films deposited on titanium and stainless steel by ion-bean-assisted sputtering 显示文摘 | Pan J Leygraf C Thierry D | 1997 | J Biomed Mater Res1997，35，3： | 1 |
| 8 | Microvascular Obstruction and the No-Reflow Phenomenon After Percutaneous Coronary Intervention显示文摘 | Ronen J Thierry Ch Geoffrey P | 2008 | Cir- culation2008，117，24： | 1 |
| 9 | An event-related potential component sensitive to images of the human body 显示文摘 | Thierry G Pegna A J Dodds C | 2006 | Neuroimage2006，16，1： | 1 |
| 10 | Strategic issues in product recovery management 显示文摘 | Thierry M Salomon M Nunen J | 1995 | California Management Review1995，37，2： | 1 |
| 11 | Complications of Scoliosis Surgery in Prader-Willi Syndrome显示文摘 | Franck Accadbled Thierry Odent Alexandre Moine Edouard Chau Christophe Glorion Gwenaelle Diene Jér?me Sales de Gauzy | 2008 | Spine2008，，4： | 1 |
| 12 | Novel antibody-therapiesfor malignant lymphoma 显示文摘 | Muller AM Rawluk J Thierry V | 2005 | Dtsch Med Wochensch2005，130，48： | 1 |
| 13 | A molecular basis for NKT cell recognition of CD1d-self-antigen显示文摘 | THIERRY M ANDREW J JAMES P | | 0，，05： | 1 |
| 14 | Use and abuse of flexible intramedullary nailing in children and adolescents显示文摘 | PIERRE L THIERRY H PIERRE J | 2006 | Pediatr Orthop2006，26，6： | 1 |
| 15 | Importance of extracellular polymeric substances from Thiobacillus ferrooxidans for bioleaching 显示文摘 | Gehrke T Telegdi J Thierry D | 1998 | Applied and Environmental Microbiology1998，64，7： | 1 |
| 16 | Rotation,scale,and translation invariant spread spectrum digital image watermarking显示文摘 | Joseph J K Ruanaidh (O) Thierry P | 1998 | Signal Processing1998，66，3： | 1 |
| 17 | Hybrid simulation of scatter intensity in industrial cone-beam computed tomography显示文摘 | THIERRY R MICELI A HOFMANN J | 2009 | Nuclear Instruments and Methods in Physics Research Section A2009，598，2： | 1 |
| 18 | Electrochemical studies of the influence of beryllium on corrosion resistance of Ni-25Cr-10Mo cast alloys for dental applications显示文摘 | PAN J GEIS-GERSTORFER J THIERRY D LEYGRAF C | 1995 | Journal of Electrochemical Society1995，142，： | 1 |
| 19 | Strategic issues in product recovery management 显示文摘 | Thierry M Salomon M van Nunen J | 1995 | California Management Review1995，37，2： | 1 |
| 20 | Sampling-based path planning on configuration-space costmaps显示文摘 | Leonard J Juan C Thierry S | 2010 | IEEE Transaction on Robotics2010，26，4： | 1 |
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