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114篇 您的检索式:作者名="TYLER F"
    题名 作者 年代 出处 被引量
1健康领域的文化能力显示文摘1背景 尽管人类对其他社会的兴趣纵贯历史的各个阶段,但是检验不同文化概念对人类健康实践的影响从20世纪才开始,当时是伴随着长期的人类学田野调查产生的,这些田野调查揭露了不同文化之间相关卫生实践的多样性、复杂性和连续性。Napier A D Ancarno C Butler B Calabrese j Chater A Chatterjee H Guesnet F Home R Jacyna S Jadhav S Macdonald A Neuendorf U Parkhurst A Reynolds R Scambler G Shamdasani S Smith S Z Stougaard-Nielsen J Thomson L Tyler N Volkmann A M Walker T Watson J Williams AC Willott C Wilson J Woolf K 2016中国卫生政策研究2016,9,2:5
2Local immunotherapy with interleuk in-2 delivered from biodegradable p olymer microspheres combined with interstitial chemotherapy:a novel treatme nt for experimental malignant glioma显示文摘OBJECTIVE:Local delivery of carmustine(BCNU)from biodegradable polymers prolon gs survival against experimental brain tumors.Moreover,paracrine administration of inte rleukin-2(IL-2)has been shown to elicit a potent antitumor immune response and to improve survival in animal brain tumor models.We r eport the use of a novel polymeric mic rosphere delivery vehicle to release IL-2.We demonstr ate both in vitro release of cytokine from the microspheres and histological evidence of the inflammatory response elicited by I L-2released from the microspheres i n the rat brain.These microspheres a re used to deliver IL-2,and biodegradable polymer wafers are used to deliver BCNU,directly at the site of an intracranially implanted glioma in the rat.The two agents administered locally show a s ynergistic effect.METHODS:Fischer 344rats challenged intracranially with 9L gliosarcoma received an intracranial implant of either empty microspheres or microspheres containing IL-2(IL-2MS ).Five days later,animals in each group were randomized to receiv e polymer implants loaded with 0,3.8,or 10%BCNU at the tumor site.RESULTS:Animals that received the combination of IL-2MS a nd 3.8%BCNU polymer(median survival,28.5d )or IL-2MS and 10%BCNU polymer(median survival,45.5d )showed significantly improved surv ival compared with animals that rece ived monotherapy with IL-2microsph eres(median survival,24d ),3.8%BCNU polymer(median survival,24d ),or 10%BCNU polymer(median survival,32.5d ).Control animals had a median survival of 18days.The combination of either 3.8or 10%BCNU polymer with IL-2MS resulted in 7and 25%long-term survivors,respectively.CONCLUSION:By showing synergy of IL-2and BCNU in an animal glioma model and using a reproducible synthetic delivery sy stem for each agent (i.e.,one that did not rely on genetic ally engineered cells or viruses),we hope that the combination of local immunotherapy and chemotherapy can take an important step closer to clinical applic ation in patients with malignant brainRhines LD DiMeco F Lawson HC Tyler BM Hanes J Olivi A Brem H 2003癌症2003,22,7:2
3文化、不平等性与卫生服务提供显示文摘1动态不平等性对基层医疗卫生人力的影响 政治、社会、文化、专业群体皆建立在一致且常规的人类行为之上。当遭受巨大变革和内外压力时,这些群体会变得十分脆弱。尤其在动荡时期,这些群体往往更关注社会和文化的差异性,而非二者的一致性。尽管社会中的个体思维和行为会呈现较大的差异,但对健康的感知具有统一性,并在更广范围人群内尤为突出,这主要归因于文化价值观的作用。广义的文化心态会随着时间和地理位置的不同而不同,就像健康的社会决定因素也会因文化类型的不同而产生差异。Napier A D Ancarno C Butler B Calabrese J Chater A Chatterjee H Guesnet F Horne R Jacyna S Jadhav S Macdonald A Neuendorf U Parkhurst A Reynolds R Scambler G Shamdasani S Smith S Z Stougaard-Nielsen J Thomson L Tyler N Volkmann A M Walker T Watson J Williams A C Willott C Wilson J Woolf K 2016中国卫生政策研究2016,9,3:2
4Nitrification of ammonical fertilizers in some California soils显示文摘Broadbent F E Tyler K B Hill G N 1957Hilgardia1957,27,:1
5医疗卫生保健文化的反思及促进健康与文化融合的建议显示文摘1医疗卫生保健文化的反思1.1健康文化与医学知识如果医务人员有充足的时间对患者进行诊断并帮助患者进行社区护理,就可在节省卫生费用的同时改善健康结果。整合型社区护理能缩小不同文化背景和群体健康需求的差异。然而,全球范围内对整合型社区护理的投入较少,原因之一就是20世纪对临床服务的重视弱化了卫生服务提供过程中的同情心理。当然,患者也对医学知识存在显性和隐性的影响(特别是当其因不遵医嘱而受到指责时)。Napier A D Ancarno C Butler B Calabrese J Chater A Chatterjee H Guesnet F Horne R Jacyna S Jadhav S Macdonald A Neuendorf U Parkhurst A Reynolds R Scambler G Shamdasani S Smith S Z Stougaard-Nielsen J Thomson L Tyler N Volkmann A M Walker T Watson J Williams A C Willott C Wilson JWoolf K 2016中国卫生政策研究2016,9,4:1
6Cyticreacfions of products ffomthe rapid hydropyrolysis of co atmospheric pressure显示文摘NELSON P F TYLER R J 1989(3): 488-4941989,,3:1
7Effect of pH on nitrogen immobilization in two California Soil 显示文摘Broad F E Tyler K B 1965Plant and Soil1965,23,:1
8Deep arid system hydrodynamics 2:Application to paleohydrologic reconstruction using vadose zone profiles from the northern Mojave Desert显示文摘Walvoord M A Phillips F M Tyler S W 2002Water Resources Research2002,38,12:1
9Effect of pH on nitrogen immobilization in two California soils显示文摘BROADBENT F E TYLER K B 1965Plant and Soil1965,23,:1
10Wet-milling,composition and functional properties of starch and protein isolated from buckwheat groats 显示文摘Zheng G H Sosulski F W Tyler R T 1998Food Research International1998,30,7:1
11Hematologic and semen quality changes in bulls with experimental eperythrozoon infection显示文摘WELLES E G TYLER J W WOLFE D F 1995Teriogenology1995,43,:1
12Eperythro-zoon infection in young bulls with scrotal and hindlimb edema,a herd outbreak显示文摘WELLES E G TYLER J W WOLFE D F 1995Teriogenology1995,43,:1
13Wet-milling,composition and functional properties of starch and protein isolated from buckwheat groats显示文摘Zheng G H Sosulski F W Tyler R T 1998Food Research International1998,30,7:1
14Characteristics of a condition following vaccination with bovine virus diarrhea vaccine显示文摘PETER C P TYLER D E RAMSEY F K 1967J Am Vet Med Assoc1967,150,:1
15Validation of radioimmunoassay for two salmon gonadotropins (GTH Ⅰ and GTH Ⅱ ) and their plasma concentrations throughout the reproductivecycle in male and female rainbow trout (Oncorhynchus mykiss) 显示文摘Prat F Sumpter J P Tyler C R 1996Biology of Reproduction1996,54,6:1
16Evaporation suppression and solar energy collection in a salt-gradient solar pond 显示文摘Ruskowitz J A Sudrez F Tyler S W 2014Solar Energy2014,99,:1
17Pigmented villonodular synovitis显示文摘Tyler W K Vidal A F Williams R J 2006J Am Acad Orthop Surg2006,14,6:1
18Wet milling,Composition and functional properties of starch and protein isolated from buckwheat grorts显示文摘Zheng G H Sosulski F W Tyler R T 1998Food Research International1998,31,7:1
19Ideal free distributions of stream fish:a model and test with minnows, Rhinichthys atratulus显示文摘Tyler J A Gilliam J F 1995Ecology1995,76,2:1
20Local delivery of mitoxantronefor the treatment of malignant brain tumors in rats 显示文摘DiMeco F Li KW Tyler BM 2002J Neuro- surg2002,97,5:1
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