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89篇 您的检索式：作者名="Tabor R"

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	题名	作者	年代	出处	被引量
1	Towards a standard diet-induced and biopsy-confirmed mouse model of non-alcoholic steatohepatitis: Impact of dietary fat source显示文摘BACKGROUND The trans-fat containing AMLN(amylin liver non-alcoholic steatohepatitis,NASH)diet has been extensively validated in C57BL/6J mice with or without the Lep^ob/Lep^ob(ob/ob)mutation in the leptin gene for reliably inducing metabolic and liver histopathological changes recapitulating hallmarks of NASH.Due to a recent ban on trans-fats as food additive,there is a marked need for developing a new diet capable of promoting a compatible level of disease in ob/ob and C57BL/6J mice.AIM To develop a biopsy-confirmed mouse model of NASH based on an obesogenic diet with trans-fat substituted by saturated fat.METHODS Male ob/ob mice were fed AMLN diet or a modified AMLN diet with trans-fat(Primex shortening)substituted by equivalent amounts of palm oil[Gubra amylin NASH,(GAN)diet]for 8,12 and 16 wk.C57BL/6J mice were fed the same diets for 28 wk.AMLN and GAN diets had similar caloric content(40%fat kcal),fructose(22%)and cholesterol(2%)level.RESULTS The GAN diet was more obesogenic compared to the AMLN diet and impaired glucose tolerance.Biopsy-confirmed steatosis,lobular inflammation,hepatocyte ballooning,fibrotic liver lesions and hepatic transcriptome changes were similar in ob/ob mice fed the GAN or AMLN diet.C57BL/6J mice developed a mild to moderate fibrotic NASH phenotype when fed the same diets.CONCLUSION Substitution of Primex with palm oil promotes a similar phenotype of biopsyconfirmed NASH in ob/ob and C57BL/6J mice,making GAN diet-induced obese mouse models suitable for characterizing novel NASH treatments.	Michelle L Boland Denise Oro Kirstine S T■lb■l Sebastian T Thrane Jens Christian Nielsen Taylor S Cohen David E Tabor Fiona Fernandes Andrey Tovchigrechko Sanne S Veidal Paul Warrener Bret R Sellman Jacob Jelsing Michael Feigh Niels Vrang James L Trevaskis Henrik H Hansen	2019	World Journal of Gastroenterology2019，25，33：	3
2	Comparative sensitivity of HBV NATs and HBsAg assays for detection of acute HBV infee- tion显示文摘	Biswas R Tabor E Hsia CC	2003	Transfusion2003，43，6：	1
3	Persistence of genetically altered fields in head and neck cancer patients:biological and clinical implications显示文摘	Tabor M P Brakenhoff R H Van Houten V M	2001	Clin Cancer Res2001，7，6：	1
4	Empirical analysis of audit uncertainty qualifications 显示文摘	T B Bell and R H Tabor	1991	Journal of Accounting Research1991，1991，：	1
5	Multiple head and neck tumors frequently originate from a single reneoplastic lesion显示文摘	Tabor M P Brakenhoff R H Ruijter-Schippers H J	2002	Am J Pathol2002，161，：	1
6	Electron density matching as a guide to surfactant design 显示文摘	TABOR R F GOLD S EASTOE J	2006	Langmuir2006，22，3：	1
7	On automating the generation of CFD models based on 3D data: industrial and biomechanical applications 显示文摘	Tabor G Bui X Fureder R	2004	European congress on computational methods in applied science and engineering2004，2428，：	1
8	Regulation of gene expression by SREBP and SCAP显示文摘	Edwards P A Tabor D Kast H R	2000	Biochim Biophys Acta2000，1529，13：	1
9	Nine-year follow-up study of a plasma-derived hepatitis B vaccine in a rural African setting显示文摘	Tabor E Cairns J Gerety R J Bayley AC	1993	J Med Virol1993，40，：	1
10	Utility Experience with Real Time Rates显示文摘	Tabors R D Schweppe F C Caramanis M C	1989	IEEE Trans on Power Systems1989，4，2：	1
11	Second primary tumors and field cancerization in oral and oropharyngeal cancer: molecular techniques provide new insights and definitions显示文摘	BRAAKHUIS B J TABOR M P LEEMANS C R	2002	Head Neck2002，24，：	1
12	Pronounced effects of ani- sotropy on plasmonic properties of nanorings fabricated by electron beam lithography显示文摘	Near R Tabor C Duan J	2012	Nano Letters2012，12，4：	1
13	Regulation of gene expression by SREBP and SCAP显示文摘	Edwards P A Tabor D Kast H R		0，，：	1
14	Optimal demand- side response to electricity spot prices for storage-type customers显示文摘	Daryanian B Bohn R E Tabors R D	1989	IEEE Trans on Power Systems1989，4，3：	1
15	Barophilic growth of bacteria from intestinal tracts of deep-sea invertebrates显示文摘	DEMING J W TABOR P S COLWELL R R	1981	Microbial ecology1981，7，1：	1
16	Multiple head and neck tumors frequently originate from a single preneoplastie lesion 显示文摘	TABOR M P BRAKENHOFF R H RUIJTERSC- HIPPERS H J	2002	Am J Pathol2002，161，：	1
17	Tmnsmission system management and pricing: new paradigms and international comparison显示文摘	Tabors R D	1994	IEEE Trans on Power System1994，19，1：	1
18	Comparative sensitivity of HBV NATs and HBsAg assays for de- tection of acute HBV infection显示文摘	Biswas R Tabor E Hsia CC	2003	Transfusion2003，43，6：	1
19	Optimal demand-side response to electricity spot prices for storage-type cus- tomers显示文摘	Daryanian B Bohn R Tabors R	1989	IEEE Transactions on Power Systems1989，4，3：	1
20	Comparative sensitivity of HBV NATs and HBsAg assays for detection of acute HBV infection 显示文摘	Biswas R Tabor E Hsia CC	2003	Transfusion2003，43，6：	1

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