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| 1 | Knockdown of FoxM1 by siRNA interference decreases cell proliferation, induces cell cycle arrest and inhibits cell invasion in MHCC-97H cells in vitro显示文摘 | Qi-fei WU Chang LIU Ming-hui TAI Dong LIU Lei LEI Rui-tao WANG Min TIAN Yi Lü | 2010 | Acta Pharmacologica Sinica2010，31，3： | 13 |
| 2 | Characterization of disinfection byproduct formation potential in 13 source waters in China显示文摘The formation potential of four trihalomethanes (THMFP) and seven haloacetic acids (HAA 7 FP) in 13 source waters taken from four major water basin areas in China was evaluated using the simulated distribution system (SDS) chlorination method.The specific ultraviolet absorbance (SUVA 254:the ratio of UV 254 to dissolved organic carbon (DOC)),which ranged between 0.9 and 5.0 L/(mg·m),showed that the organic compounds in different source waters exhibited different reactivities with chlorine.The HAA 7 FP of source waters ranged from 20 to 448 μg/L and the THMFP ranged from 29 to 259 μg/L.The HAA 7 FP concentrations were higher than the THMFP concentrations in all but one of the samples.Therefore,the risks of haloacetic acids (HAAs) should be of concern in some source waters.TCM (chloroform) and BDCM (bromodichloromethane) were the major THM constituents,while TCAA (trichloroacetic acid) and DCAA (dichloroacetic acid) were the major HAA species.Br-THM (brominated THM species) were much higher than BrHAA (brominated HAA species),and the formation of Br-DBP (Br-THM and Br-HAA) should be of concern when the bromide concentration is over 100 μg/L. | Junzhi Zhang Jianwei Yu Wei An Juan Liu Yongjing Wang Youjun Chen Jia Tai Min Yang | 2011 | Journal of Environmental Sciences2011，23，2： | 13 |
| 3 | Comparison of peripapillary retinal nerve fiber layer thickness between myopia severity groups and controls显示文摘AIM: To compare the peripapillary retinal nerve fiber layer(RNFL) thickness measured via optical coherence tomography(OCT) between different groups of myopia severity and controls. METHODS: This was a prospective cross-sectional study. All subjects underwent a full ophthalmic examination, refraction, visual field analysis and A-scan biometry. Myopic patients were classified as low myopia(LM) [spherical equivalent(SE) from greater than-0.5 D, up to-3.0 D], moderate myopia(MM; SE greater than-3.0 D, up to-6.0 D) and high myopia(HM; SE greater than-6.0 D). The control group consisted of emmetropic(EM) patients(SE from +0.5 D to-0.5 D). A Zeiss Cirrus HD-OCT machine was used to measure the peripapillary RNFL thickness of both eyes of each subject. The mean peripapillary RNFL thickness between groups was compared using both analysis of variance and analysis of covariance.RESULTS: A total of 403 eyes of 403 subjects were included in this study. The mean age was 31.48±10.23 y. There were 180(44.7%) eyes with EM, 124(30.8%) with LM, 73(18.1%) with MM and 26(6.5%) with HM. All groups of myopia severity had a thinner average RNFL than the EM group, but after controlling for gender, age, and axial eye length, only the HM group differed significantly from the EM group(P=0.017). Likewise, the superior, inferior and nasal RNFL was thinner in all myopia groups compared to controls, but after controlling for confounders, only the inferior quadrant RNFL was significantly thinner in the HM group, when compared to the EM group(P=0.017). CONCLUSION: The average and inferior quadrant RNFL is thinner in highly myopic eyes compared to emmetropic eyes. Refractive status must be taken into consideration when interpreting the OCT of myopic patients, as RNFL thickness varies with the degree of myopia. | Evelyn Li Min Tai Jiunn Loong Ling Eng Hui Gan Hussein Adil Wan-Hiram Wan-Hazabbah | 2018 | International Journal of Ophthalmology(English edition)2018，11，2： | 7 |
| 4 | 急性视神经炎后视神经功能与视觉诱发电位的研究(英文)显示文摘目的:比较视神经炎患者和正常人的视神经功能与视觉诱发电位。方法:本研究为2011年9月至2013年2月在马来西亚大学眼科医院进行的横断面研究。研究包含在检查前3mo至2y间发生特发性神经炎一次的视神经炎患者20例和10例正常人。眼科检查包括视力、色觉、视觉灵敏度、视野和视觉诱发电位。独立t检验用于比较视神经炎组与对照组视神经功能和VEP参数的差异。在参数非正态分布时,Mann-Whitney试验用于比较两组间的中位数。结果:视神经炎组的平均年龄为30.8岁。在视神经炎发作至评估期间的平均持续时间为6.6个月。视神经炎组视力较差,平均LogM AR值(0.52)明显高于对照组(P=0.001)。色觉下降,视神经炎组的平均值为63%(P=0.001)。视神经炎患者的对比敏感度在四个空间频率上均有所下降[3CPD(P=0.029),6CPD(P=0.026),12CPD(P=0.002)、18CPD(P=0.006)]。视神经炎组的视野下降有统计学意义(P<0.001)。与对照组相比,视神经炎组的VEP P100潜伏期有轻微延长。但使用棋盘格模式1或2时,VEP潜伏期的差异不显著。视神经炎患者的VEP振幅较高,但两组差异无统计学意义。结论:视神经炎急性发作,平均6mo后视神经功能(即视力、色觉、对比敏感度和视野)显著下降。视神经炎组和对照组的VEP振幅和潜伏期无显著差异。VEP可能不是理想的诊断视神经炎既往发作史的试验,尽管VEP参数在浮动后趋于正常。 | Evelyn Tai Li Min Ng Seok Hui Jakiyah Daud Raja Azmi Mohd Noor Wan-Hazabbah Wan Hitam | 2017 | 国际眼科杂志2017，17，5： | 5 |
| 5 | Outgassing analysis of molecular glass photoresists under EUV irradiation显示文摘A device was designed and assembled to analyze the outgassing of molecular glass(MG)photoresists under extreme ultraviolet(EUV)exposure.The outgassing of the photoresists with different components and different concentrations of tert-butoxycarbonyl(t-Boc),photo-generated acid(PAG),and acid quencher was systematically investigated.Based on experiments,some solutions for reducing the outgassing of MG photoresists were proposed. | CHEN Li XU Jian YUAN Hua YANG Shu Min WANG Lian Sheng WU Yan Qing ZHAO Jun CHEN Ming LIU Hai Gang LI Sha Yu TAI Ren Zhong WANG Shuang Qing YANG Guo Qiang | 2014 | Science China Chemistry2014，57，12： | 4 |
| 6 | 影响增殖性糖尿病视网膜病变玻璃体切除术后视力改善的因素(英文)显示文摘目的:分析影响增殖性糖尿病视网膜病变(PDR)玻璃体切除术后视力改善的因素。方法:回顾性分析。收集2014-01/2014-12在马来西亚吉打州,亚罗士打Sultanah Bahiyah医院收治的PDR行玻璃体切除术病例资料,包括1y内患者统计,基线视力(VA)和LogMAR术后最佳矫正视力。使用IBM SPSS Statistics Version 22.0进行数据分析。结果:共103例患者。平均年龄51.2y。在多变量分析中,每个0 logMAR基线VA的1 logMAR术前正偏差与0.859logMAR的术后改善相关(P<0.001)。同样,术前附着的黄斑与玻璃体切除术后的logMAR视力改善相关(b=0.374,P=0.003)。无虹膜新血管和无术后并发症与玻璃体切除术后改善的logMAR视力相关,分别为1.126(P=0.001)和0.377(P=0.005)。无长效眼内填充与玻璃体切除术后logMAR视力改善相关,为0.302(P=0.010)。结论:玻璃体切除术后与视力改善的相关因素是:术前视力较差,黄斑附着,无虹膜新生血管,无术后并发症和未使用长效眼内填充物。了解视力改善的因素将有助于玻璃体视网膜手术的决策。 | Evelyn Tai Li Min Goh Yihu Wan-Hazabbah Wan Hitam Haslina Mohd Ali | 2017 | 国际眼科杂志2017，17，8： | 4 |
| 7 | Effect of Perched Water Tables on Aluminosilicate Stability and Soil Genesis显示文摘The mineral stability and solute activities of soil solution extracted from selected horizons of seven studied pedons of Alfisols in Kentucky, USA, and the relationship between distribution of iron-manganese concretions and the restrictive layers were investigated. The results showed that the genesis and development of these soils and mineral weathering trends were strongly influenced by the depth of bedrock and the presence of perched water tables at lithic (limestone) interfaces due to the dissolution and buffering effect of limestone bedrock. The extractable Mg/Ca ratio as depth function and soil depth above bedrock could be used as indices of weathering and degree of soil development. Maximum iron-manganese concretion accumulation was found to occur in the horizon overlying clay horizon (>40% clay) with a sharp increase in clay content (>10%), which suggested that zones of Fe-Mn concretion accumulation in soils of the Inner Bluegrass Region appeared to be a sensitive genetic indicator of argillic horizons with restrictive permeability. | ZHANG MIN , GONG ZITONG and A. D. KARATHANASIS College of Resources and Environment, Shandong Agricultural University, Tai’an 271018 (China) Institute of Soil Science, the Chinese Academy of Sciences, Nanjing 210008 (China) College of Agriculture, U | 2000 | Pedosphere2000，10，3： | 4 |
| 8 | Treatment preferences in men with erectile dysfunction: an open label study in Korean men switching from sildenafil citrate to tadalafil显示文摘瞄准:为 sildenafil 柠檬酸盐或 tadalafil 评估耐心的偏爱(为可勃起的机能障碍的治疗可得到的 PDE-5 禁止者[编辑]) 并且为这些偏爱估计潜在的原因。方法:这开标签的研究在拿 sildenafil 的朝鲜的人,上被进行在学习入口以前的至少 6 个星期为编辑追随者屏蔽,病人们继续 sildenafil 治疗 4 个星期,然后在一个 1 星期的冲刷时期以后,换到 tadalafil 8 个星期。病人们然后在一个延期阶段期间继续了他们选择的治疗。Psychosocial 因素(时间担心,自然,性自信) 用心理、人与人之间的关系规模(对) 被评估,当剂量预定到性尝试时,模式从耐心的日记被估计。结果:现在的学习注册了 160 个朝鲜的人(意味着年龄 55 年) 与 585 天的优先的中部的 sildenafil 使用。在延期阶段期间, 73.7% 病人选择拿 tadalafil,而 26.3% 选择了 sildenafil (P < 0.001 ) 。在从 sildenafil 切换到 tadalafil 以后,意味着担心分数从 2.54 ~ 2.42 减少了的对时间(P = 0.002 ) ,没有统计上,有效差量在性自然和自信分数在 sildenafil 和 tadalafil 评价阶段之间观察了。做的性尝试 < 4 h 到≤ 36 h 剂量以后在 tadalafil 评价阶段期间与 17.5% 相比在 sildenafil 评价阶段期间发生在 4.5% 病人。结论:在经历 sildenafil 和 tadalafil 以后,病人的多数为 tadalafil 展出了偏爱。这偏爱可能被精神分析聚会因素影响,例如减少的时间担心,和为性欲活动可得到的机会的一扇更宽广的窗户。 | Tai Young Ahn Sung Won Lee Sae-Woong Kim Dae Yul Yang Nam Cheol Park Kweon-Sik Min Kwangsung Park Jae-Seung Paick Yulia Dyachkova Trisha Dwight Myung-Sea Luke Lee | 2007 | Asian Journal of Andrology2007，9，6： | 3 |
| 9 | Alteration of oncogenic IGF-II gene methylation status associates with hepatocyte malignant transformation显示文摘Background: Oncogenic insulin-like growth factor-II(IGF-II) is overexpressed in hepatocellular carcinoma(HCC). The present study aimed to analyze the dynamic alteration of IGF-II CpG site methylation status and its molecular mechanism in HCC progression. Methods: IGF-II alterations were observed in rat hepatocarcinogenesis models induced by 2-acetylaminofluorene. Liver IGF-II expression was compared by immunohistochemistry or tissue IGF-II specific concentration(nmol/mg protein). Status of human IGF-II promoter 3(P3) or rat IGF-II P2 CpG site methylation was amplified by methylation-specific polymerase chain reaction(MSP). Serum IGF-II levels were quantitatively detected by an enzyme-linked immunosorbent assay. Results: The levels of hepatic IGF-II expression were significantly elevated in the HCC group( P < 0.001). The unmethylation rate of IGF-II P3 CpG sites was 100% in the HCC-, 52.5% in the paracancerous-, and none(0%) in the distal noncancerous-tissues. Abnormal IGF-II expression was related to differentiation degree, tumor invasion, and positive HBV-DNA(all P < 0.001), with a negative correlation between P3 methylation degree and IGF-II expression. There was a positive correlation between liver IGF-II specific concentration and circulating IGF-II level( r = 0.97, P < 0.001). Significantly negative correlation was found between IGF-II P2 CpG site methylation and circulating IGF-II( r s =-0.89, P < 0.001) or liver IGF-II level( r s =-0.84, P < 0.001). Conclusions: The increase of serum IGF-II and the alteration of oncogenic gene IGF-II methylation may be biomarkers for HCC diagnosis and DNA methylation may be the therapeutic target of HCC. | Bo-Jun Tai Min Yao Wen-Jie Zheng Yu-Cheng Shen Li Wang Jian-Ying Sun Meng-Na Wu Zhi-Zhen Dong Deng-Fu Yao | 2019 | Hepatobiliary & Pancreatic Diseases International2019，18，2： | 3 |
| 10 | Increase of ambient formaldehyde in Beijing and its implication for VOC reactivity显示文摘影响大气哦激进的预算和 tropospheric 臭氧生产,周围的甲醛(HCHO ) 是关键氧化不稳定的有机化合物(OVOC ) 之一。我们在场在在北京的夏日的甲醛列密度上的变化从臭氧监视检索了在 2005 和 2011 之间的仪器(OMI ) 。尽管有一些显著差别, HCHO 的卫星列与可得到的基于地面的大小相关很好。直角的距离回归(ODR ) 方法被用来估计在卫星列和地面级的集中之间的比率,而平常的最少的广场(OLS ) 方法被用来适合周围的甲醛的趋势。从列在 712 ppbv 并且稳定地的范围的 HCHO 导出的甲醛集中以 0.64 ppbv/yr 的近似的率增加了(7.8% 在 2005 水平) 与 51% 的无常。VOC 反应确定了借助于哦损失率出现了从甲醛和乙醛增加贡献,在 2010 在 2005 ~ 40% 从 35% 升起,并且减少从人为的 VOC 的贡献,在 2010 在 2005 ~ 40% 从 49% 落下。更多的注意应该对理解增加甲醛到臭氧形成潜力的网反馈被给予。 | Qian Zhang Min Shao Yang Li Si Hua Lu Bin Yuan Wen Tai Chen | 2012 | Chinese Chemical Letters2012，23，9： | 3 |
| 11 | NUMERICAL SIMULATION OF ATOMIZATION RAINFALL AND THE GENERATED FLOW ON A SLOPE显示文摘This article studies the atomization rainfall and the generated flow on a slope by numerical simulations.The atomization rainfall is simulated by a unified model for splash droplets and a suspended mist,and the distribution of the diameter of splash rain drops is analyzed.The slope runoff generated by the atomization rainfall is simulated by a depth-averaged 2-D model,and the localization of the rainfall intensity in space is specially considered.The simulation results show that:(1) the median rain size of the atomization rainfall increases in the longitudinal direction at first,then monotonously decreases,and the maximum value is taken at the longitudinal position not in consistent with the position where the maximum rain intensity is taken.In the lateral direction the median rain size monotonously decreases,(2) since the atomization rainfall is distributed in a strongly localized area,it takes a longer time for its runoff yield to reach a steady state than that in the natural rainfall,the variation ranges of the water depth and the velocity in the longitudinal and lateral directions are larger than those in the natural rainfall. | LIU Shi-he TAI Wei FAN Min LUO Qiu-shi | 2012 | Journal of Hydrodynamics2012，24，2： | 2 |
| 12 | 曲安奈德联合地塞米松上睑板内注射治疗小儿春季角结膜炎(英文)显示文摘马来西亚理科大学5a来使用曲安奈德混悬型注射液与地塞米松磷酸钠治疗小儿春季角结膜炎(VKC)的疗效研究。10例联合注射治疗患者注射1mo后症状有所改善。其中4例患者主要并发症为眼压增高。6mo内有4例患者复发。研究发现上睑板联合注射两种皮质类固醇治疗春季角膜炎的临床效果与文献报道使用单一皮质类固醇剂非常相似。然而,该治疗方法眼压升高的风险较大。 | Rajendran Punitan Haslinda Said Evelyn Li Min Tai Ismail Shatriah | 2018 | 国际眼科杂志2018，18，4： | 2 |
| 13 | 马来西亚视神经萎缩的临床特点及病因(英文)显示文摘目的:研究在马来西亚非青光眼视神经萎缩的病因及临床特点。方法:一系列回顾性的研究分析马来西亚理科大学校医院眼诊所在2007/2011年间被诊断为非青光眼视神经萎缩的患者。至少随访1a。评估这些患者的医疗记录及汇编调查结果。结果:100例患者符合选择标准,56%的患者双眼都参与研究。主要症状为视力模糊(61%),除了视力模糊外还出现神经方面病症(18%),视野狭窄(9%)。大多数患者(63%)患眼视力下降到3/60以下。主要的病因是颅内占位性病变(26%),先天性疾病(13%),脑积水(12%),创伤(12%)及血管因素(12%)。对大多数患者(67%)采用保守治疗。不管其病因,视神经萎缩都伴有不同程度的视功能障碍。随访1a后,50%的患者出现不同程度的视觉障碍。结论:视神经萎缩主要的病因是颅内占位性病变,其次分别是先天性疾病,创伤和血管疾病。在诊断之前常常就出现视觉和神经上的症状,而疾病显著地影响着视力的变化。为了早期诊断视神经萎缩,当视力模糊的主诉为非特异性时,应该高度怀疑本病。 | Evelyn Tai Li Min Jessica Mani Penny Tevara Zunaina Embong Raja Azmi Mohd Noor Wan-Hazabbah Wan Hitam | 2014 | 国际眼科杂志2014，14，2： | 2 |
| 14 | Peduncin, A New Indole Alkaloid from Pueraria peduncualris显示文摘A new indole alkaloid, peduncin was isolated from the roots of Pueraria peduncularis. Its structure was established as 1 by NMR spectroscopic and X-ray crystallographic analysis. | Na LI Qi Tai ZHENG Zhi Da MIN | 2001 | Chinese Chemical Letters2001，12，10： | 2 |
| 15 | Ideal Cardiovascular Health Metrics and Coronary Artery Calcification in Northern Chinese Population:A Cross-sectional Study显示文摘Objective Coronary artery calcification(CAC) is a well-established risk predictor of coronary heart disease events and is recognized as an indicator of subclinical atherosclerosis.Methods A cross-sectional study consisting of 2999 participants aged ≥40 years from the Jidong community of Tangshan City,an industrial and modern city of China,was conducted between 2013 and 2014 to examine the association between the ideal cardiovascular health(CVH) metrics and CAC.The ideal CVH metrics were determined based on the definition of the American Heart Association(AHA).The participants were then grouped into 4 categories according to the quartiles of their CVH metric scores as follows:first quartile(0-2),second quartile(3),third quartile(4),and fourth quartile(5-7).CAC was assessed by using high-pitch dual-source CT,and patients were identified based on thresholds of 0,10,100,or 400 Agatston units,as per common practice.Results The prevalence of subclinical atherosclerosis was 15.92%,13.85%,6.76%,and 1.93%,determined by using the CAC scores at thresholds of 0,10,100,and 400 Agatston units,respectively.Compared with the group in the first quartile,the other three CVH groups had a lower odds ratio of CAC >0 after adjusting for age,sex,income level,education level,and alcohol use in the logistic regression analysis.The odds ratios in these groups were 0.86 [95% confidence interval(CI),0.63-1.17;P<0.05],0.75(95% CI,0.55-1.02;P<0.05),and 0.49(95% CI,0.35-0.69;P<0.05),respectively.These associations of CAC with the CVH metrics were consistent when different CAC cutoff scores were used(0,10,100,or 400).Conclusion The participants with more-ideal cardiovascular metrics had a lower prevalence of subclinical atherosclerosis determined according to CAC score.Maintaining an ideal cardiovascular health may be valuable in the prevention of atherosclerosis in the general population. | LUO Tai Yang LIU Xiao Hui DAI Tian Yi LIU Xin Min ZHANG Qian DONG Jian Zeng | 2016 | Biomedical and Environmental Sciences2016，29，7： | 2 |
| 16 | 在结核病患者中通过评估解剖结构和视功能变化早期发现乙胺丁醇毒性(英文)显示文摘目的:通过评估比较治疗前后解剖结构和视功能的变化,包括视网膜神经纤维厚度、图形视觉诱发电位、传统视神经功能检查,早期检测乙胺丁醇毒性。方法:前瞻性研究,包括参加马来西亚理科大学医院的短期治疗观察项目的36例72眼结核病患者。视力和视神经功能检查由同一位研究者进行。同样,Humphrey自动视野检查、光学相干断层扫描(OCT)检查视网膜神经纤维厚度(RNFL)和图形视觉诱发电位(PVEP)均由同一位技术人员进行。在开始乙胺丁醇治疗前和治疗3mo后各进行检查一次。结果:乙胺丁醇治疗前后视力、彩色视觉、光亮度、红光反射和眼底检查无明显改变。然而,平均视野缺损在治疗后较前变差(P=0.010)。OCT和PVEP有显著变化,P100潜伏期延长、幅度降低,RNFL在各个象限均增厚(P<0.05)。结论:通过OCT检测RNFL厚度以及使用PVEP检测P100波峰潜伏期和幅度,可以在传统视神经功能检查异常之前,发现乙胺丁醇治疗后早期解剖结构和视功能的亚临床改变。 | Jessica Mani Penny Tevaraj Tan Chai Keong Evelyn Tai Li Min Muhammed Julieana Raja Azmi Mohd Noor Wan-Hazabbah Wan Hitam | 2017 | 国际眼科杂志2017，17，11： | 2 |
| 17 | Comparative study of resection and radiofrequency ablation in the treatment of solitary colorectal liver metastases显示文摘 | Hyuk Hur Yong Taek Ko Byung Soh Min Kyung Sik Kim Jin Sub Choi Seung Kook Sohn Chang Hwan Cho Heung Kyu Ko Jong Tai Lee Nam Kyu Kim | 2009 | The American Journal of Surgery2009，，6： | 2 |
| 18 | The three human monocyte subsets: implications for health and disease显示文摘 | Kok Loon Wong Wei Hseun Yeap June Jing Yi Tai Siew Min Ong Truong Minh Dang Siew Cheng Wong | 2012 | Immunologic Research (-)2012，，1： | 1 |
| 19 | Structure and Magnetic Properties of LaCo_(13-X)M_X Intermetallic Compounds显示文摘StructureandMagneticPropertiesofLaCo_(13-X)M_XIntermetallicCompoundsWUJianMin;LIFeng;TAILiChiandZHEMGQunStructureandMagneticP... | WU Jian Min LI Feng TAI Li Chi and ZHEMG Qun | 1994 | Journal of Iron and Steel Research(International)1994，1，1： | 1 |
| 20 | Multi-country study on the prevalence and clinical features of peripheral arterial disease in asian type 2 diabetes patients at high risk of atherosclerosis显示文摘 | Sang Youl Rhee Heng Guan Zhi Min Liu Stephen Wing-Keung Cheng Sarwono Waspadji Patricio Palmes Tong Yuan Tai Sompongse Suwanwalaikorn Young Seol Kim | 2006 | Diabetes Research and Clinical Practice2006，，： | 1 |
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