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| 1 | 《2015年美国风湿病学会/欧洲抗风湿联盟痛风分类标准》摘译显示文摘痛风是以尿酸钠(monosodium urate,MSU)结晶在关节液和组织中沉积为特点的疾病,是最常见的关节炎。各国痛风患病率分别为美国3.9%、法国0.9%、英国1.4%-2.5%、德国1.4%,新西兰欧裔和毛利人分别为3.2%和6.1%。在过去的10年中,已有治疗痛风的新药面世或正在进行临床试验。无论是药物临床试验、痛风危险因素观察性研究、 | 张冰清 盛峰 谷俊杰 杨丹 梁广宇 张昀 曾学军 Neogi T Jansen TL Dalbeth N | 2015 | 中华临床免疫和变态反应杂志2015,9,4: | 322 |
| 2 | Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations显示文摘 | Thompson MC Fuller C Hogg TL Dalton J Finkelstein D Lau CC Chintagumpala M Adesina A Ashley DM KeUie SJ Taylor MD Curran T Gajjar A Gilbertson RJ | 2006 | 中国神经肿瘤杂志2006,4,1: | 17 |
| 3 | 澳大利亚临床共识指南:儿童卒中的诊断和急性期处理显示文摘卒中是导致儿童死亡的十大原因之一,幸存的致残患儿将面临几十年的残疾生活,给患儿及其家庭带来了巨大负担。由于安全性和有效性的证据有限,以及诊断的延误,目前卒中患儿无法接受再灌注治疗。儿童卒中诊断和急性期处理的澳大利亚临床共识指南,旨在最大限度地减少临床诊疗中的不确定性,并记录与成人卒中不同的危险因素、病因和假性卒中情况的最佳证据。临床问题的阐述来自于对2007年至2017年数据库的系统检索,但仅限于英语和儿科研究。该指南应用SIGN方法和国家健康与医学研究委员会系统对证据进行筛选和分类,通过推荐、评估、发展和评价系统(GRADE系统)对推荐进行强弱分级。该指南提供了60多项基于证据的推荐,以帮助参与院前和急症处理的临床医师快速识别儿童卒中,选择最合适的初步检查方案来确定诊断、明确病因,并选择最恰当的干预措施以挽救脑组织、预防复发。同时,指南也提供了颅内压和先天性心脏病管理方面的推荐。该指南的实施需要将院前和急诊系统重组,包括建立区域性卒中网络,建立儿科卒中疾病编码,快速MRI,以及对能够提供再灌注治疗的初级儿科卒中中心进行认证。该指南能够审核治疗的基准时间线,获得急性期的干预措施及预后判断。它还将促进澳大利亚儿童卒中登记的发展,并与国际登记处建立数据联系,以便准确收集卒中发病率、治疗和结果相关的数据。 | Medley TL Miteff C Andrews I Ware T Cheung M Monagle P Mandelstam S Wray A Pridmore C Troedson C Dale RC Fahey M Sinclair A Walsh P Stojanovski S Macka MT 徐佳丽(译) 吴川杰(译) 肖潇(译) 吕俊萱(译) 张博维(译) 吉训明(译) | 2019 | 中国脑血管病杂志2019,16,4: | 9 |
| 4 | 儿童期肥胖、成年期肥胖和心血管风险因子显示文摘过去30年,儿童超重或肥胖的发生率明显增加[1]。儿童期肥胖是死亡率增加的预测因子,这主要是由于儿童期肥胖可导致心血管疾病发生率增加。相关的预测研究提示"肥胖流行症"可能改变目前心血管疾病死亡率下降的趋势,使现今儿童的寿命缩短。 | Juonala M Magnussen CG Berenson GS Venn A Burns TL Sabin MA Srinivasan SR Daniels SR Davis PH Chen W Sun C Cheung M Viikari JS Dwyer T Raitakari OT 叶鹏 | 2012 | 中华高血压杂志2012,20,1: | 6 |
| 5 | Expression and release of IL-29 by mast cells and modulation of mast cell behavior by IL-29显示文摘 | He, S Zhang, H Chen, H Yang, H Huang, T Chen, Y Lin, J Wang, F Chen, X Li, TL Yang, P | 2010 | 南京医科大学学报(自然科学版)2010,30,11: | 6 |
| 6 | Relationship between skin fold thickness and insulin resistance in the essential hypertensive patients in Vietnam显示文摘Previous studies reported a close relationship between obesity and insulin resistance in the essential hypertensive patients. Objective In this study, we examined the relationship between the skin fold thickness and insulin resistance then developed a formula to estimate the insulin resistance index according to the skin fold thickness in the essential hypertensive patients. Subjects and Methods Medical records of 80 patients (37 males, 43 females) were reviewed and the data were tabulated. Anthropometric indexes (including height, weight, waist circumference, hip circumference, and skins fold thickness at 5 fatty difference points on the Erdheim diagram), fasting plasma glucose and insulin concentration were recorded. The mean age was 57.0±9.2 years. The insulin resistance index was calculated following the Homeostasis Model Assessment (HOMA) formula. Results Compared with the group with BMI<23kg/m2, the group with BMI≥23 kg/m2 had higher fasting insulin concentration (8.85 ± 4.97 pmol/L vs 15.60 ± 8.70 pmol/L, P<0.001 ) and higher insulin resistance index in (2.15±1,24 vs 3.76±2.22, P<0.001). No significant difference in fasting plasma insulin concentration,insulin resistance index between male and female was observed (P>0.05). There was a positive correlation between skin fold thickness and the fasting insulin concentration and insulin resistance index. The skin fold thickness at point A8 had the best coefficient correlated with fasting plasma insulin(r=0.79, P<0.001) and insulin resistance index (r= 0.79, P < 0.001). A formula to estimate the insulin resistance index by skin fold thickness at point A8 as: Insulin resistance index = 0.12 × [skin fold thickness at A8 point (mm)] - 1.Conclusion: In the essential hypertensive patients, the formula to estimate insulin resistance index as 0.12 × [skin fold thickness at A8 point (mm)]-1 may predict accurately the level of insulin resistance. | Toan C Nguyen Khoa TA Pham Quyen TL Do Cuong T Nguyen Diep D Nguyen Vinh G Le Cong D Nguyen | 2005 | Journal of Geriatric Cardiology2005,2,4: | 4 |
| 7 | Migration of retinal pigment epithelium cells in vitro is regulated by protein kinase C显示文摘 | Murphy TL Sakamoto T Hinton DR | 1995 | Exp Eye Res1995,60,6: | 2 |
| 8 | Di-triton molecular structure in ^6H显示文摘 | Akimunc tl Yamagata T Nakayama S | 2003 | Phys Roy2003,67,5: | 1 |
| 9 | Oxidation causes melanin fluorescnce显示文摘 | Peter K Gabriele T Thamos TL | 2001 | Invest Ophthalmol Vis Sci2001,42,1: | 1 |
| 10 | Review: Adiponeetin - the missing link between maternal adiposity, placental transport and fetalgrowth 显示文摘 | Aye IL Powell TL Jansson T | 2013 | Placenta2013,34,: | 1 |
| 11 | TLR-4, IL-1R and TNF-R signaling to NF-kappaB: variations on a common theme 显示文摘 | Verstrepen L Bekaert T Chau TL | 2008 | Cell Mol Life Sci2008,65,19: | 1 |
| 12 | An evolution in themanagement of sinonasal inverting papilloma显示文摘 | HAN JK SMITH TL LOEHRL T | 2001 | Laryngoscope2001,111,8: | 1 |
| 13 | Oral ganciclovir dosing in transplant recipients and dialysis patients based on renal function 显示文摘 | Peskovitz MD Pruett TL Gonwa T | 1998 | Transplantation1998,66,: | 1 |
| 14 | Arrested B lympho- poiesis and persistence of activated B cells in adult interleukin 7 (-/) - mice显示文摘 | Carvalho TL Mota-Santos T Cumano A | 2001 | J Exp Med2001,194,8: | 1 |
| 15 | Claudin 14knockout mice,a model for autosomal recessive deafness DFNB29,are deaf due to cochlear hair cell degeneration显示文摘 | Ben-Yosef T Belyantseva IA Saunders TL | 2003 | Hum Mol Genet2003,12,16: | 1 |
| 16 | Complications of laparoscopic paraesophageal hernia repair显示文摘 | Trus TL Bax T Richardson WS | 1997 | J Gastmintest Surg1997,1,3: | 1 |
| 17 | MUC1 is involved in trophoblast transendothelial migration显示文摘 | Thirkill TL Cao T Stout M | 2007 | Biochim Biophys Aeta2007,1773,6: | 1 |
| 18 | Blood loss and postoperative complications associated with transure- thral resection of the prostate after pretreatment with dutasteride 显示文摘 | Hahn RG Fagerstrom T Tammela TL | 2007 | BJU Int2007,99,: | 1 |
| 19 | The Noncoding RNA Taurine Upregulated Gene1Is Required for Differentiation of the Murine Retina显示文摘 | Young TL Matsuda T Cepko CL | 2005 | Current Biology2005,15,6: | 1 |
| 20 | An evolution in the management of sinonesal inveting papilloma显示文摘 | Han JK Smith TL Loehrl T | 2001 | Largngoscope2001,111,: | 1 |