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| 1 | 青少年甘油磷酸胆碱代谢和心血管病的危险因素:一项队列研究显示文摘甘油磷酸胆碱(glycerophosphocholine,GPC)代谢物可调节动脉粥样硬化,从而导致心血管病风险。临床前期心血管病可能从青春期就开始。研究人员应用靶向血清脂质组学鉴定一组新的GPC,并测试在青春期时这些GPC中的任何一种是否与心血管病传统危险因子,如过量内脏脂肪、升高的血压、胰岛素抵抗和致动脉粥样硬化血脂异常相关。 | Syme C Czajkowski S Shin J Abrahamowicz M Leonard G Perron M Richer L Veillette S Gaudet D Strug L Wang Y Xu H Taylor G Paus T Bennett S Pausova Z 刘莉 叶鹏 | 2016 | 中华高血压杂志2016，24，10： | 3 |
| 2 | Frequent amplification of a chr19q13.41 microRNA polycistron in aggressive primitive neuroectodermal brain tumors显示文摘 | Li M Lee KF Lu Y Clarke I Shih D Eberhart C Collins VP Van Meter T Picard D Zhou L Boutros PC Modena P Liang ML Scherer SW Bouffet E Rutka JT Pomeroy SL Lau CC Taylor MD Gajjar A Dirks PB Hawkins CE Huang A. | 2009 | 中国神经肿瘤杂志2009，7，4： | 3 |
| 3 | Vaccination of mice with a cocktail DNA vaccine induces a Th1-type immune response and partial protection against schistosoma japonicum infection显示文摘 | Zhang Y Taylor MG Johansen MV | 2001 | Vaccine2001，20，56： | 2 |
| 4 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017，25，5： | 2 |
| 5 | 在有煽动性、非煽动性的腹的疼痛显型的孩子的 interleukin-6 和桅杆房间的反的关系显示文摘 AIM: To investigate interleukin-6 (IL-6), mast cells, enterochromaffin cells, 5-hydroxytryptamine, and substance P in the gastrointestinal mucosa of children with abdominal pain. METHODS: Formalin-fixed paraffin-embedded gas-trointestinal biopsy blocks from patients (n = 48) with non-inflammatory bowel disease (irritable bowel syndrome and functional abdominal pain) and inflammatory bowel disease were sectioned and stained for IL-6, mast cells, enterochromaffin cells, 5-hydroxytryptamine, and substance P. All children had chronic abdominal pain as part of their presenting symptoms. Biopsy phenotype was confirmed by a pathologist, blinded to patient information. Descriptive statistics, chi-square, and independent sample t tests were used to compare differences between the inflammatory and non-inflammatory groups. RESULTS: The cohort (n = 48), mean age 11.9 years (SD = 2.9), 54.2% females, 90% Caucasian, was comprised of a non-inflammatory (n = 26) and an inflammatory (n = 22) phenotype. There was a significant negative correlation between substance P expression and mast cell count (P = 0.05, r = -0.373). Substance P was found to be expressed more often in female patient biopsies and more intensely in the upper gastrointestinal mucosa as compared to the lower mucosa. There were significantly increased gastrointestinal mucosal immunoreactivity to IL-6 (P = 0.004) in the inflammatory phenotype compared to non-inflammatory. Additionally, we found significantly increased mast cells (P = 0.049) in the mucosa of the non-inflammatory phenotype compared to the inflammatory group. This difference was particularly noted in the lower colon biopsies. CONCLUSION: The findings of this study yield preliminary evidence in identifying biomarkers of undiagnosed abdominal pain in children and may suggest candidate genes for future evaluation. | Wendy A Henderson Ravi Shankar Tara J Taylor Arseima Y Del Valle-Pinero David E Kleiner Kevin H Kim Nader N Youssef | 2012 | World Journal of Gastrointestinal Pathophysiology2012，3，6： | 2 |
| 6 | Testing and evaluation of nonchromated coating systems for aerospace applications 显示文摘 | Osborne H J Blohowiak K Y Taylor S R | 2001 | Prog Org Coat2001，41，： | 1 |
| 7 | Schistosoma japonicum myosin:cloning, expression and vaccination studies with the homologue of the Schistosoma mansoni myosin fragment IrV-5 显示文摘 | Zhang Y Taylor MG Bickle QD | 1998 | Parasite hnmunol1998，20，： | 1 |
| 8 | MIMO Receiver Using Reduced Complexity Sequence Estimation With Channel Estimation and Tracking 显示文摘 | Y H Kho D P Taylor | 2009 | IEEE Transactions on on Vehicular Technology2009，58，2： | 1 |
| 9 | Antigen retrieval immunohistochemis- try:review and future prospects in research and diagnosis over two decades显示文摘 | Shi SR Shi Y Taylor CR | 2011 | J Histochem Cytochem2011，5，1： | 1 |
| 10 | Nutrition intervention trials in Linxian,China:supplementation with specific vitamin/mineral combinations,cancer incidence,and disease-specific mortality in the general population 显示文摘 | BLOT W J LI J Y TAYLOR P R | 1993 | Journal of the National Cancer Institute1993，85，18： | 1 |
| 11 | Variation of the point spectrum under compact perturbations显示文摘 | HERRERO D A Taylor T J Wang Z Y | 1988 | Operator Theory: Advances and Applications1988，32，： | 1 |
| 12 | Disease-causing mutations in parkin impair mitochondrial ubiquitination,aggregation,and HDAC6 dependent mitophagy显示文摘 | Lee JY Naqano Y Taylor JP | | 0，，04： | 1 |
| 13 | Biochemical complementation of chalcone synthase mutants defines a role for flavonols in functional pollen显示文摘 | Mo Y Nagel C Taylor L P | 1992 | Proceedings of the National Academy of Sciences1992，89，15： | 1 |
| 14 | Advances toward bioapplications of Carbon nanotubes显示文摘 | Lin Y Taylor S Li HP | 2004 | J Mater Chem2004，14，4： | 1 |
| 15 | The brain entry of risperidone and 9 - hydroxyrisperidone is greatly limited by P - glycoprotein 显示文摘 | Wang JS Roan Y Taylor RM | 2004 | Inter J Neur2004，7，： | 1 |
| 16 | Variation of the point spectrum under compact perturbations 显示文摘 | HERRERO D A TAYLOR T J WANG Z Y | 1988 | Oper Theory Adv Appl1988，32，： | 1 |
| 17 | Multiple sensors on pulsed eddy current detection for 3-D subsurface crack assessment显示文摘 | Tian G Y Sophian A Taylor D | 2005 | IEEE Sensors Journal2005，5，1： | 1 |
| 18 | Protective immunity against avian influenza induced by a fowlpox virus recombinant显示文摘 | Taylor J Weinberg R Kawaoka Y | 1988 | Vaccine1988，，6： | 1 |
| 19 | Comparison of broiler performance when fed diets containing grain from yield gard rootworm ( MON863 ), yield gard plus ( MON810xMON863 ), nontransgenic control, or commercial reference corn hybrids 显示文摘 | Taylor M L Hyun Y Hartenll G F | 2003 | Poultry Science2003，82，： | 1 |
| 20 | Comparison of the associations of body mass index and measures of central adiposity and fat mass with coronary heart disease,diabetes,and all-cause mortality:a study using data from 4 UK cohorts显示文摘 | Taylor AE Ebrahim S Ben-Shlomo Y | 2010 | Am J Clin Nutr2010，91，： | 1 |
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