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| 1 | Outcome of surgical resection in Klatskin tumors显示文摘Cholangiocarcinomas are the second most frequent primary hepatic malignancy,and make up from 5% to 30% of malignant hepatic tumours.Hilar cholangiocarcinoma(HCC) is the most common type,and accounts for approximately 60% to 67% of all cholangiocarcinoma cases.There is not a staging system that permits us to compare all series and extract some conclusions to increase the long-survival rate in this dismal disease.Neither the extension of resection,according to the sort of HCC,is a closed topic.Some authors defend limited resection(mesohepatectomy with S1,S1 plus S4b-S5,local excision for papillary tumours,etc.) while others insist in the compulsoriness of an extended hepatic resection with portal vein bifurcation removed to reach cure.As there is not an ideal adjuvant therapy,R1 resection can be justified to prolong the survival rate.Morbidity and mortality rates changed along the last decade,but variability is the rule,with morbidity and mortality rates ranging from 14% to 76% and from 0% to 19%,respectively.Conclusion:Surgical resection continues to be the main treatment of HCC.Negative resection margins achieved with major hepatic resections are associated with improved outcome.Preresectional management with biliary drainage,portal vein embolization and staging laparoscopy should be considered in selected patients.Additional evidence is needed to fully define the role of orthotopic liver transplant.Portal and lymph node involvement worsen the prognosis and long-term survival,and surgery is the only option that can lengthen it.Improvements in adjuvant therapy are essential for improving long-term outcome.Furthermore,the lack of effective chemotherapy drugs and radiotherapy approaches leads us to can consider R1 resection as an option,because operated patients have a longer survival rate than those who not undergo surgery. | Alejandro Serrablo Luis Tejedor | 2013 | World Journal of Gastrointestinal Oncology2013，5，7： | 18 |
| 2 | High-Strain Fiber Bragg Gratings for Structural Fatigue Testing of Military Aircraft显示文摘这份报纸在调查可靠性的工作的一个试验性的程序上报导,耐久性,并且为是的申请纤维布拉格栅栏(FBG ) 包装在结构的疲劳测试军事平台期间散布了紧张传感器。传感器可靠性上的 FBG 制造过程的影响被调查。另外,为宽广区域的包装的方法论并且 FBG 察觉到到防卫平台的数组被开发并且测试装表面。 | Claire DAVIS Silvia TEJEDOR Ivan GRABOVAC James KOPCZYK Travis NUYENS | 2012 | Photonic Sensors2012，2，3： | 5 |
| 3 | Mesenchymal stem cells require the peripheral immune system for immunomodulating effects in animal models of multiple sclerosis显示文摘Multiple sclerosis(MS)is a chronic inflammatory disease of the central nervous system(CNS)that affects oligodendrocytes and myelin.Loss of myelin leads to progressive axonal damage and neuronal death resulting in neurodenegeration and functional disability.Several inflammatory factors influence the development of this neurological disorder.It is generally accepted that autoreactive T lymphocytes migrate towards | Laura Salinas Tejedor Thomas Skripuletz Martin Stangel Viktoria Gudi | 2016 | Neural Regeneration Research2016，11，1： | 4 |
| 4 | Reconstruction after pancreatoduodenectomy:Pancreatojejunostomy vs pancreatogastrostomy显示文摘Pancreatic surgeons try to find the best technique for reconstruction after pancreatoduodenectomy(PD) in order to decrease postoperative complications,mainly pancreatic fistulas(PF).In this work,we compare the two most frequent techniques of reconstruction after PD,pancreatojejunostomy(PJ) and pancreatogastrostomy(PG),in order to determine which of the two is better.A systematic review of the literature was performed,including major meta-analysis articles,clinical randomized trials,systematic reviews,and retrospective studies.A total of 64 articles were finally included.PJ and PG are usually responsible for most of the postoperative morbidity,mainly due to the onset of PF,being considered a major trigger of life-threatening complications such as intra-abdominal abscess and hemorrhagia.The included systematic reviews reported a significant difference only in the incidence of intraabdominal collections favouring PG.PF,delayed gastric emptying and mortality were not different.Although there was heterogeneity between these studies,all were conducted in specialized centers by highly experienced surgeons,and the surgical care was likely to be similar for all the studies.The disadvantages of PG include an increased incidence of delayed gastric emptying and of main pancreatic duct obstruction due to overgrowth by the gastric mucosa.Exocrine function appears to be worse after PG than after PJ,resulting in severe atrophic changes in the remnant pancreas.Depending on the type of PJ or PG used,the PF rate and other complications can also be different.The best method to deal with the pancreatic stump after PD remains questionable.The choice of method of pancreatic anastomosis could be based on individual experience and on the surgeon's preference and adherence to basic principles such as good exposure and visualization.In conclusion,up to now none of the techniques can be considered superior or be recommended as standard for reconstruction after PD. | Tatiana Gómez Ana Palomares Mario Serradilla Luis Tejedor | 2014 | World Journal of Gastrointestinal Oncology2014，6，9： | 3 |
| 5 | Fluorescence analysis of carrier rat and human erythrocytes loaded with FITC-dextran 显示文摘 | Alvarez FJ Herraez A Tejedor MC | 1996 | Cytometry1996，24，2： | 2 |
| 6 | Refractive changes induced by form deprivation in the mouse eye显示文摘 | Tejedor J de la Villa P | 2003 | Invest Ophthalmol Vis Sci2003，44，1： | 1 |
| 7 | Infarct size by contrast en- hanced cardiac magnetic resonance is a stronger predictor of outcomes than left ventricular ejection fraction or end-systolic volume index: prospective cohort study显示文摘 | Wu E Ortiz JT Tejedor P | 2008 | Heart2008，94，： | 1 |
| 8 | Direct metabolomics for plant cells by live single-cell mass spectrometry 显示文摘 | Fujii T Matsuda S Tejedor ML Esaki T Sakane I Mizu- no H Tsuyama N Masujima T | 2015 | Nat Protoc2015，10，： | 1 |
| 9 | Delivery to macrophages of Interleukin 3 loaded in mouse erythrocytes显示文摘 | Lotero LA Tejedor MC | 2000 | Biosci Rep2000，20，5： | 1 |
| 10 | Thin-film transmission IR spectroscopy as an in situ probe of the gas solid interface in photocatalytic processes显示文摘 | SHO K Isabel M Tejedor T | 2004 | Journal of Photochemistry and Photobiology A:Chemistry2004，163，： | 1 |
| 11 | Sildeuafil restores cognitive function without affecting β - amyloid burden in a mouse model of Alzheimer's disease显示文摘 | CUADRADO - TEJEDOR M HERVIAS I RICOBARAZA A | 2011 | Br J Pharmacol2011，164，8： | 1 |
| 12 | Long-term outcome and predictor variables in the treatment of acquired esotropia with botulinum toxin 显示文摘 | Rodriguez JM | 2001 | Invest Ophthalmol Vis Sci2001，42，11： | 1 |
| 13 | A 17bp dele- tion in the Bone Morphogenetic Protein 15 (BMP15) gene is associated to increased prolificacy in the Rasa Aragonesa sheep breed 显示文摘 | Monteagudo L V Ponz R Tejedor M T | 2009 | Animal Reproduction Science2009，110，1： | 1 |
| 14 | Miliary tuberculosis due to BCG in an asymptomatic patient: initial onset or a condition not yet described? 显示文摘 | Cobas Paz A Garcia Tejedor JL Gonza1ez Pifieiro A | 2010 | Arch Bronconeumol2010，46，： | 1 |
| 15 | Addisonian crisis as the presenting feature of bilateral primary adrenal lymphoma显示文摘 | Serrano S Tejedor L Garcia B | 1993 | Cancer1993，71，： | 1 |
| 16 | Titanium Dioxide-Coated Silica Waveguides for the Photocatalytic Oxidation of Formic Acid in Water 显示文摘 | Miller L W Tejedor M I Anderson M A | 1999 | Environmental Science & Teehnology(S0013-936X)1999，33，12： | 1 |
| 17 | The spatio-temporal and subcellular expression of the candidate Down syndrome gene Mnb/Dyrkl A in the developing mouse brain suggests distinct sequential roles in neuronal development 显示文摘 | Hammerle B Elizalde C Tejedor FJ | 2008 | Eur J Neurosci2008，27，5： | 1 |
| 18 | Prediction of pneumococcal conjugate vaccine effectiveness against invasive pneumococcal disease using opsonophagocytic activity and antibody concentrations determined by enzyme-linked immunosorbent assay with 22F adsorption显示文摘 | Schuerman L Wysocki J Tejedor J C | 2011 | Clin Vaccine Immunol2011，18，12： | 1 |
| 19 | Addisonian crisis as the presenting feature of bilateral primary adrenal lymphoma显示文摘 | Tejedor L Garcia B | 1993 | Cancer1993，71，12： | 1 |
| 20 | Assessment of Toxicity of River Water and Effluents by the Bioluminescence Assay Using Photobacterium phosphoreum显示文摘 | FERNANDEZ A TEJEDOR C CABRERA F | 1995 | Water Research1995，29，5： | 1 |
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