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| 1 | Analysis of orthopedic surgical procedures in children with cerebral palsy显示文摘BACKGROUND Orthopedic surgery in children with cerebral palsy(CP)aims to improve function and prevent deformities.Each child’s condition in CP is unique and many covariables influence surgical decision-making including a patient's age and their functional level.Little is known about the frequency of different types of orthopedic surgery in children with CP who have varied functional levels,particularly in countries from Latin America.AIM To assess the type of orthopedic surgical procedures in relation to age and gross motor function in children with CP.METHODS This retrospective study included all children with CP(n=245)treated with elective orthopedic surgery at a Uruguayan university hospital between October 2010 and May 2016 identified from a surgical database.Eighteen children(7%)were lost to follow-up due to missing medical charts.Demographics,gross motor function classification(GMFCS),and orthopedic surgeries were obtained from the medical records of 227 children.Chi-squared tests and analysis of variance were used to assess the frequency of surgery,accounting for GMFCS levels.Mean age for soft tissue vs bone surgery was compared with the independent samples t-test.RESULTS A total of 711 surgical procedures were performed between 1998 and 2016.On average,children had 3.1 surgical procedures and the mean age at first surgery was 8.0 years.There were no significant differences in age at first surgery among GMFCS levels(P=0.47).The most common procedures were lower leg soft tissue surgery(n=189,27%),hip tenotomy(n=135,19%),and hamstring tenotomy(n=104,14%).For children with GMFCS level Ⅰ,the mean number of surgeries per child[1.8(range 1-9)]differed significantly at P<0.05 in children with GMFCS levels Ⅱ[3.2(1-12)],Ⅲ[3.2(1-8)],Ⅳ[3.3(1-13)],and Ⅴ[3.6(1-11)].Within Ⅱ,Ⅲ,Ⅳ,and Ⅴ,there was no significant difference in mean number of surgeries per child when comparing across the groups.The proportion of soft tissue surgery vs bone surgery was higher in GMFCS levels Ⅰ-Ⅲ(80%-85%)compared to levels IV(68%)and V(55%)(P<0.05).CONCLUSION The frequency of surgical procedures per child did not increase with higher GMFCS level after level Ⅰ.However,the proportion of bone surgery was higher in GMFCS levels Ⅳ-Ⅴ compared to Ⅰ-Ⅲ. | Ignacio Rehbein Viviana Teske Ignacio Pagano Alejandro Cúneo María Elena Pérez Johan von Heideken | 2020 | World Journal of Orthopedics2020，11，4： | 2 |
| 2 | The elF2 kinase PERK and the integrated stress response facilitate activation of ATF6 dur- ing endoplasmic reticulum stress显示文摘 | Teske BF Wek SA Bunpo P | 2011 | Mol Biol Cell2011，22，22： | 1 |
| 3 | Subacute digoxintoxicosis in the Beagle Dog显示文摘 | Teske R H Bishop S P Righter H F | 1976 | Toxicology and Applied Phar-macology1976，35，： | 1 |
| 4 | Serrsitive and rapid quantification of the cannabinoid receptor agonist naphthalen-l-yl-(1-pentylindol-3-yl) methanone (JWH- 018) in human serum by liquid chromatography-tandem mass spectrometry显示文摘 | Teske J Welier J P Fieguth A | | J Chromatogr B0，，： | 1 |
| 5 | Sensitive and rapid quantification of the cannabinoid receptor agonist naphthalen-l-yl-( l-pentylindol-3-yl ) methanone ( JWH- 018) in human serum by liquid chromatography-tandem mass spectrometry 显示文摘 | Teske J Weller J P Fieguth A | 2010 | J Chromatogr B2010，878，： | 1 |
| 6 | Polyethylene glycol-L-asparaginase versus native L-asparaginase in canine non-Hodgkin's lymphoma显示文摘 | Rutteman GR van Heerade P | 1990 | Eur J Cancer1990，26，： | 1 |
| 7 | A survey of flagellate diversity at four deep-sea hydrothermal vents in the Eastern Pacific Ocean using structural and molecular approaches 显示文摘 | Atkins M S Teske A P Anderson O R | 2000 | Journal of Eukaryotic Micro- biology2000，47，： | 1 |
| 8 | Regulatory Policymaking in American States:A Review of Theories and Evidence显示文摘 | TESKE P | 2000 | Political Research Quarterly2000，53，4： | 1 |
| 9 | Phylogeographic structure of Octopus vulgaris in South Africa revisited: identi- fication of a second lineage near Durban Harbour显示文摘 | TESKE P R OOSTHUIZEN A Papadopoulos I | 2007 | Mar Biol2007，151，： | 1 |
| 10 | Community composition of a hypersaline endoevaporitic microbial mat 显示文摘 | Sorensen K B Canfield D E Teske A P | 2005 | Appl Environ Microbiol2005，71，： | 1 |
| 11 | Microbial communities of deep marine subsurface sediments:molecular and cultivation surveys 显示文摘 | Teske A P | 2006 | G eomicrobiology Journal2006，23，6： | 1 |
| 12 | Predisposition to late-onset obesity in GIRK4 knockout mice 显示文摘 | Perry Cydne A Mareo P Teske Jennifer A | 2008 | Proc Nag Acad Sci2008，105，： | 1 |
| 13 | Expanding frontie in deep subsurface micro- biology 显示文摘 | AMEND J P TESKE A A | 2004 | PNeogeogr Paleoelim Paleoeeo12004，219，： | 1 |
| 14 | Microbial communities of deep marine subsurface sediments:Molecular and cultivation surveys显示文摘 | Teske A P | | 0，，06： | 1 |
| 15 | Molecular identifi- cation of bacteria from a cocuhure by denaturing gradient gel electrophoresis of 16S ribosomal DNA fragments as a tool for isolation in pure cultures显示文摘 | Teske A Sigalevich P Cohen Y | 1996 | Appl Environ Micro- bio11996，62，11： | 1 |
| 16 | The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress显示文摘 | Teske B F Wek S A Bunpo P Cundiff J K McClintick J N Anthony T G | 2011 | Mol Biol Cell2011，22，： | 1 |
| 17 | The eIF2a kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress 显示文摘 | Teske BF Wek SA Bunpo P | 2011 | Mol Biol Cell2011，22，22： | 1 |
| 18 | The elF2 kinase PERK and the integrated stress response facilitate activation of A TF6 during endoplasmic reticulum stress显示文摘 | Teske BF Wek SA Bunpo P | 2011 | Mol Bio Cell2011，22，43： | 1 |
| 19 | Disseminated 'Mycobacterium genavense' infection in patients with AIDS显示文摘 | Bottger EC Teske A Kirschner P | 1992 | Lancet1992，340，8811： | 1 |
| 20 | Community composition of a hypersaline endoevaporitic microbial mat 显示文摘 | Sorensen K B Canfield D E Teske A P | 2005 | Appl Environ Microbiol2005，71，11： | 1 |
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