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| 1 | Use of venous-to-arterial carbon dioxide tension difference to guide resuscitation therapy in septic shock显示文摘The mixed venous-to-arterial carbon dioxide(CO_2)tension difference[P(v-a) CO_2]is the difference between carbon dioxide tension(PCO_2) in mixed venous blood(sampled from a pulmonary artery catheter) and the PCO_2 in arterial blood.P(v-a) CO_2 depends on the cardiac output and the global CO_2 production,and on the complex relationship between PCO_2 and CO_2 content.Experimental and clinical studies support the evidence that P(v-a) CO_2 cannot serve as an indicator of tissue hypoxia,and should be regarded as an indicator of the adequacy of venous blood to wash out the total CO_2generated by the peripheral tissues.P(v-a) CO_2 can be replaced by the central venous-to-arterial CO_2 difference(△PCO_2),which is calculated from simultaneous sampling of central venous blood from a central vein catheter and arterial blood and,therefore,more easy to obtain at the bedside.Determining the △PCO_2 during the resuscitation of septic shock patients might be useful when deciding when to continue resuscitation despite a central venous oxygen saturation(SCVO_2) > 70%associated with elevated blood lactate levels.Because high blood lactate levels is not a discriminatory factor in determining the source of that stress,an increased △PCO_2(> 6 mmHg)could be used to identify patients who still remain inadequately resuscitated.Monitoring the △PCO_2 from the beginning of the reanimation of septic shock patients might be a valuable means to evaluate the adequacy of cardiac output in tissue perfusion and,thus,guiding the therapy.In this respect,it can aid to titrate inotropes to adjust oxygen delivery to CO_2 production,or to choose between hemoglobin correction or fluid/inotrope infusion in patients with a too low ScvO_2 related to metabolic demand.The combination of P(v-a) CO_2 or △PCO_2 with oxygen-derived parameters through the calculation of the P(v-a) CO_2 or △PCO_2/arteriovenous oxygen content difference ratio can detect the presence of global anaerobic metabolism. | Jihad Mallat Malcolm Lemyze Laurent Tronchon Beno?t Vallet Didier Thevenin | 2016 | World Journal of Critical Care Medicine2016，5，1： | 25 |
| 2 | The Simultaneous Repression Of CCR and CAD, Two Enzymes of the Lignin Biosynthetic Pathway, Results in Sterility and Dwarfism in Arabidopsis thaliana显示文摘Cinnamoyl CoA reductase (CCR ) 和 cinnamyl 白酒脱氢酶(CAD ) 催化 monolignol 生合成的最后步骤。在 Arabidopsis,一 CCR 基因(CCR1, At1g15950 ) 并且二 CAD 基因(CAD C At3g19450 和 CAD D At4g34230 ) 涉及这条小径。三倍的恶棍 c 恶棍 d ccr1 变异的、命名 ccc,被获得。这异种显示严格的矮子显型和男绝育。在 ccc 的木质素内容成熟的茎被归结为 50% 野类型的水平。另外,茎木质素结构严重地被影响,在抵抗内部单位的契约和加入由戏剧的丰富出现进象 coniferaldehyde 那样的 monolignol 先锋的聚合物 sinapaldehyde,和 ferulic 酸。男绝育由于在花药内层的木质化的缺乏,它引起花药裂开并且花粉版本的失败。ccc hypolignified 茎积累黄酮醇 glycosides, sinapoyl malate 和 feruloyl malate 的更高的数量,它建议酉分的小径的重定向。因此, CAD 和 CCR 的缺席, monolignol 小径的关键酶,比他们中的每的单个缺席在显型上有更严重的后果。另一 CCR 感应(CCR2, At1g80820 ) 并且另一 CAD (CAD1, At4g39330 ) 不补偿主要 CCR 和 CAD 活动的缺席。CCR 和 CAD 活动的这缺乏不仅影响木质化,而且严重地影响植物的发展。当试着减少植物的木质素内容以便便于 lignocellulose-to-bioethanol 变换过程时,这些后果必须小心地被考虑。 | Johanne Thevenin Brigitte Pollet Bruno Letarnec Luc Saulnier Lionel Gissot Alessandra Maia-Grondard Catherine Lapierre Lise Jouanin | 2011 | Molecular Plant2011，4，1： | 18 |
| 3 | Direct-forcing immersed boundary lattice Boltzmann simulation of particle/fluid interactions for spherical and non-spherical particles显示文摘 | A. Eshghinejadfard A. Abdelsamie G. Janiga D. Thevenin | 2016 | Particuology2016，14，2： | 5 |
| 4 | Catalytic Combustion of Methane over Cerium-Doped Palladium Catalysts 显示文摘 | Thevenin P O Alcalde A Pettersson L J | 2003 | J Catal2003，215，1： | 1 |
| 5 | Protective effect of anethol dithiolthione against acetaminophen hepatotoxicity in mice显示文摘 | Warnet J M Christen M O Thevenin M | 1989 | Pharmacol Toxicol1989，65，： | 1 |
| 6 | Laminar premixed hydrogen/air counterflow flame simulations using flame prolongation of ILDM with differential diffusion显示文摘 | Gicquel O Darabiha N Thevenin D | 2000 | Proceedings of the Combustion Institute2000，28，2： | 1 |
| 7 | Evaluation of'Candidascore'in critically ill patients:aprospective,multicenter,observational,cohort study显示文摘 | Leroy G Lambiotte F Thevenin D | 2011 | Ann Intensive Care2011，1，1： | 1 |
| 8 | Transforming growth factor-beta suppresses human B lymphocyte Ig production by inhibiting synthesis and the switch from the membrane form to the secreted form of Ig mRNA显示文摘 | Kehrl JH Thevenin C Rieckmann P | 1991 | J Immunol1991，146，11： | 1 |
| 9 | Quantitative dynamic MRI and loealisation of non-palpable prostate cancer 显示文摘 | Comud F Beuvon F Thevenin F | 2009 | Prog Urol2009，19，： | 1 |
| 10 | Both caffeoyl Coenzyme A 3-O-methyltransferase 1 and caffeic acid O-methyltransferase 1 are involved in redundant functions for lignin, flavonoids and sinapoyl malate biosynthesis in Arabidopsis 显示文摘 | Do C T Pollet B Thevenin J | 2007 | Planta2007，226，： | 1 |
| 11 | Types du Prodrome de paleontology stratigraphique universelle d'Orbigny显示文摘 | Thevenin A | 1906 | Ann Paleont Pairs1906，112，： | 1 |
| 12 | Results of 32 allograft prosthesis composite reconstructions of the proximal femur显示文摘 | Biau DJ Larousserie F Thevenin F | 2010 | Clon Orthop Relat Res2010，468，3： | 1 |
| 13 | Accurate boundary conditions for multieomponent reactive flows 显示文摘 | Baum M Poinsot T Thevenin D | 1994 | Journal of Computational Physics1994，116，： | 1 |
| 14 | Dynamics of flame/vortex interactions 显示文摘 | RENARD P H THEVENIN D ROLON J C | 2000 | Progress in Energy and Combustion Science2000，26，3： | 1 |
| 15 | In vitro discrimination of fluoroquinolones toxicity on tendon cells: involvement of oxidative stress显示文摘 | Pouzaud F Bemard-Beaubois K Thevenin M | 2004 | J Pharmacol Exp Ther2004，308，1： | 1 |
| 16 | Interaction of a Gaussian acoustic wave with a turbulent premixed flame 显示文摘 | Laverdant A Thevenin D | 2003 | Combustion and flame2003，134，： | 1 |
| 17 | Both caffeoyl coenzyme A 3-O-methyltransferase 1 and caffeic acid O-methyltransferase 1 are involved in redundant functions for lignin,flavonoids and sinapoyl malate biosynthesis in Arabidopsis显示文摘 | Do C T Pollet B Thevenin J | 2007 | Planta2007，226，5： | 1 |
| 18 | Influence of the deposition parameters on the texture of boron nitride thin films synthesized in a microwave plasma-enhanced reactor显示文摘 | Thevenin P Eliaoui M Ahaitouf A | 2006 | Surface and Coatings Technology2006，200，2223： | 1 |
| 19 | Transforming growth factor-beta suppresses human B lymphocyte Ig production by inhibiting synthesis and the switch from the membrane form to the secreted form of Ig mRNA显示文摘 | Kehrl JH Thevenin C Rieckmann P | 1991 | J Immunol1991，146，11： | 1 |
| 20 | Interaction between lead and different binders 显示文摘 | Thevenin G Pera J | 1999 | Cement and Concrete Research1999，29，10： | 1 |
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