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| 1 | Long-term survival following radiofrequency ablation of colorectal liver metastases: A retrospective study显示文摘AIM: To retrospectively evaluate the long-term survivalof patients that received radiofrequency ablation(RFA) therapies of colorectal liver metastases. METHODS: In 2005 to 2008, RFA of 105 colorectal liver metastases(CRLM) were performed on 49 patients in our institution. The liver metastases were evaluated, both before and after ablation therapies, with contrast enhanced computerised tomography and contrast enhanced ultrasonography. Histological evidence of malignant liver metastases was obtained in the few instances where contrast enhanced ultrasonography gave equivocal results. Accesses to the CRLM were guided ultrasonically in all patients. The data obtained from records of these ablations were retrospectively analysed and survival data were compared with existing studies in the literature.RESULTS: 1-, 2-, 3-, 4- and 5-year survival rates, when no stringent selection criteria were applied, were 92%, 65%, 51%, 41% and 29% respectively. To explore the impact of the number and size of CRLM on patients' survival, an exclusion of 13 patients(26.5%) with number of CRLM ≥ 5 and tumour size ≥ 40 mm resulted in 1-, 2-, 3-, 4- and 5-year survival rates improving to 94%, 69%, 53%, 42% and 31% respectively. It is of note that 9 of 49 patients developed extra-hepatic metastases, not visible or seen on pretreatment scans, just after RFA treatment. These patients had poorer survival. The development of extra-hepatic metastases in nearly 20% of the patients included in our study can partly account for modestly lower survival rates as compared with earlier studies in the literature.CONCLUSION: Our study underscores the fact that optimum patients' selection before embarking on RFA treatment is vitally important to achieving a superior outcome. | Simeon Niyi Babawale Thomas MandФe Jensen Jens BrФndum FrФkjr | 2015 | World Journal of Gastrointestinal Surgery2015，7，3： | 11 |
| 2 | Interleukin-10 Signaling in Regulatory T Cells Is Required for Suppression of Th17 Cell-Mediated Inflammation显示文摘 | Ashutosh Chaudhry Robert M. Samstein Piper Treuting Yuqiong Liang Marina C. Pils Jan-Michael Heinrich Robert S. Jack F. Thomas Wunderlich Jens C. Brüning Werner Müller Alexander Y. Rudensky | 2011 | Immunity2011，，4： | 2 |
| 3 | Emphysematous cystitis:a review of 135 cases显示文摘 | Thomas AA Lane BR Thomas AZ | | 0，，： | 1 |
| 4 | Spatial and temporal temperature trends on the Yurman Plateau (Southwest China) during 1961-2004 显示文摘 | Fan Z Br/iuning A Thomas A | 2011 | International Journal of Climatology2011，31，14： | 1 |
| 5 | Effect of pharmacotherapy on rate of decline of lung function in chronic 3bstructive pulmonary disease: results from the TORCH study显示文摘 | Celli BR Thomas NE Anderson JA | 2008 | Am J Respir Crit Care Med2008，178，4： | 1 |
| 6 | The anatomical relationship between the posterior interosseous nerve and the supinator muscle显示文摘 | Thomas SJ Yakin DE Parry BR | 2009 | J Hand Surg (Am)2009，25，： | 1 |
| 7 | Aneurysmal subarachnoid hemorrhage in elderly patients: long-term outcome and prognostic factors in an interdisciplinary treatment approach显示文摘 | Karsten Sch?ller Maike Massmann Gertraud Markl Mathias Kunz Gunther Fesl Hartmut Brückmann Thomas Pfefferkorn J?rg-Christian Tonn Christian Schichor | 2013 | Journal of Neurology2013，，4： | 1 |
| 8 | Comparative evaluation of serum antioxidant levels in periodontally diseased patients: An interventional study显示文摘 | Thomas B Madani SM Prasad BR | 2014 | Contemp Clin Dent2014，5，3： | 1 |
| 9 | Cholangiocarcinoma 显示文摘 | Khan SA Thomas HC Davidson BR | 2005 | Lancet2005，366，9493： | 1 |
| 10 | Application of the CALIOP layer product to evaluate the vertical distribution of aerosols estimated by global models: AeroCom phase I results显示文摘 | Koffi Brigitte Schulz Michael Bréon Francois-Marie Griesfeller Jan Winker David Balkanski Yves Bauer Susanne Berntsen Terje Chin Mian Collins William D. Dentener Frank Diehl Thomas Easter Richard Ghan Steven Ginoux Paul Gong Sunling Horowi | 2012 | EN2012，，1： | 1 |
| 11 | Cholangiocarcinoma 显示文摘 | Khan SA Thomas HC Davidson BR | 2005 | Lancet2005，366，9493： | 1 |
| 12 | Effect of pharmacotherapy on rate of decline of lung function in chronic obstructive pulmonary disease: result from the TORCH Study 显示文摘 | Celli BR Thomas NE Anderson JA | 2008 | M J Respir Crit Care Med2008，178，4： | 1 |
| 13 | Effect ofpharmacotherapy on rate of decline of lung function in chronic obstructive pulmonary disease: results from the TORCH study 显示文摘 | Celli BR Thomas NE Anderson JA | 2008 | Am J Respir Crit Care Med2008，178，4： | 1 |
| 14 | Cholangiocarcinoma 显示文摘 | Khan SA Thomas HC Davidson BR | 2005 | Lancet2005，366，9493： | 1 |
| 15 | Cholangiocarcino-ma显示文摘 | Khan SA Thomas HC Davidson BR | 2005 | Lancet2005，366，9493： | 1 |
| 16 | Chdangio carcinoms显示文摘 | Khan SA Thomas HC Davidson BR | 2005 | Lancet2005，366，5： | 1 |
| 17 | Lyons Heterologous expression of human mPRa, mPRf3 and mPRy in yeast confirms their ability to function as membrane progesterone receptors 显示文摘 | Smith JL Kupchak BR Thomas J | 2008 | Steroids2008，73，11： | 1 |
| 18 | Effect of pharmacotherapy on rate of decline of lung function in chronic obstructive pulmonary disease:results from the TORCH study 显示文摘 | Celli BR Thomas NE Anderson JA | 2008 | Am J Respir Crit Care Med2008，178，4： | 1 |
| 19 | Extracellular DNA traps are associated with the pathogenesis of TRALI in humans and mice显示文摘 | Thomas GM Carbo C Curtis BR | 2012 | Blood2012，119，26： | 1 |
| 20 | Evaluation of mi- cronutrient (zinc, copper and iron) levels in periodontitis patients with and without diabetes mellitus type 2: A bio- chemical study 显示文摘 | Thomas B Gautam A Prasad BR | 2013 | Indian Dent Res2013，24，4： | 1 |
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