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| 1 | Gastric emptying, postprandial blood pressure, glycaemia and splanchnic flow in Parkinson's disease显示文摘AIM: To determine gastric emptying, blood pressure, mesenteric artery blood flow, and blood glucose responses to oral glucose in Parkinson's disease. METHODS: Twenty-one subjects(13 M, 8 F; age 64.2 ± 1.6 years) with mild to moderate Parkinson's disease(Hoehn and Yahr score 1.4 ± 0.1, duration of known disease 6.3 ± 0.9 years) consumed a 75 g glucose drink, labelled with 20 MBq 99mTc-calcium phytate. Gastric emptying was quantified with scintigraphy, blood pressure and heart rate with an automated device, superior mesenteric artery blood flow by Doppler ultrasonography and blood glucose byglucometer for 180 min. Autonomic nerve function was evaluated with cardiovascular reflex tests and upper gastrointestinal symptoms by questionnaire. RESULTS: The mean gastric half-emptying time was 106 ± 9.1 min, gastric emptying was abnormally delayed in 3 subjects(14%). Systolic and diastolic blood pressure fell(P < 0.001) and mesenteric blood flow and blood glucose(P < 0.001 for both) increased, following the drink. Three subjects(14%) had definite autonomic neuropathy and 8(38%) had postprandial hypotension. There were no significant relationships between changes in blood pressure, heart rate or mesenteric artery blood flow with gastric emptying. Gastric emptying was related to the score for autonomic nerve function(R = 0.55, P < 0.01). There was an inverse relationship between the blood glucose at t = 30 min(R =-0.52, P < 0.05), while the blood glucose at t = 180 min was related directly(R = 0.49, P < 0.05), with gastric emptying. CONCLUSION: In mild to moderate Parkinson's disease, gastric emptying is related to autonomic dysfunction and a determinant of the glycaemic response to oral glucose. | Laurence G Trahair Thomas E Kimber Katerina Flabouris Michael Horowitz Karen L Jones | 2016 | World Journal of Gastroenterology2016,22,20: | 5 |
| 2 | Buckling analysis design of steel frame显示文摘 | Trahair N S | 2009 | Journal of Constructional Steel Rrsearch2009,65,7: | 1 |
| 3 | Enteral diet composition alters development of the GIT and other fetal organs显示文摘 | Trahair J F Sangild P T | 1999 | Gastroenterology1999,116,: | 1 |
| 4 | Intestinal Macromolecule Absorption in the Fetal Pig after Infusion of Colostrums Inutero显示文摘 | SANGLID P T TRAHAIR J F LOFTAGER M K | 1999 | Pediatr Res1999,45,: | 1 |
| 5 | In-plane inelastic buckling and strengths of steel arches 显示文摘 | Pi Y L Trahair N S | 1996 | Journal of Structural Engineering ASCE1996,122,7: | 1 |
| 6 | Flexural-torsional stability of arch显示文摘 | Papangelis T P Trahair N S | 1987 | J Structural Engineering ASCE1987,113,4: | 1 |
| 7 | Flexural-torsional buckling test on arches显示文摘 | Papangelis T P Trahair N S | 1987 | J Structural Engineering ASCE1987,113,7: | 1 |
| 8 | Out-of-plane inelastic buckling and strength of steel arches 显示文摘 | Pi Y L Trahair N S | 1998 | Journal of Structural Engineering ASCE1998,124,2: | 1 |
| 9 | Flexural-torsional buckling of arch显示文摘 | PAPANGELIS J P TRAHAIR N S | 1987 | Journal of Structural Engineering ASCE1987,113,4: | 1 |
| 10 | In-plane buckling and design of steel arches显示文摘 | Pi Y L Trahair N S | 1999 | Journal of Structural Engineering1999,125,11: | 1 |
| 11 | In-plane buckling and design of steel arches 显示文摘 | Pi Y L Trahair N S | 1999 | Journal of Structural Engineering1999,125,11: | 1 |
| 12 | Flexural-torsional buckling 'of monosymmetric arches显示文摘 | TRAHAIR N S PAPANGELIS J P | 1987 | Journal of Struc- tural Engineering1987,113,10: | 1 |
| 13 | Nonlinear inelastic analysis of steel beam-columns Ⅰ:Theory显示文摘 | Pi Y L Trahair N S | 1994 | Journal of Structural Engineering1994,120,7: | 1 |
| 14 | In-plane buckling and design of steel arches 显示文摘 | Pi Yonglin Trahair N S | 1999 | Journal of Structural Engineering1999,125,11: | 1 |
| 15 | Nonlinear inelastic analysis of steel beam-columns Ⅱ:Application显示文摘 | Pi Y L Trahair N S | 1994 | Journal of Structural Engineering1994,120,7: | 1 |
| 16 | Energy equation for beam lateral buckling显示文摘 | Yong L P Trahair N S Rajasekaran S | 1992 | Journal Structural Engineering ASCE1992,118,6: | 1 |
| 17 | Out-o&plane inelastic buckling and strength of steel arches 显示文摘 | PI Y L TRAHAIR N S | 1998 | Journal of Structural Engineering ASCE1998,124,2: | 1 |
| 18 | Stability of Monosymmetric Beams and Cantilevers 显示文摘 | Anderson J M Trahair N S | 1972 | Journal of the Structural Division1972,98,: | 1 |
| 19 | Out-of-plan inelastic buckling and strength of steel arches显示文摘 | Pi Y L Trahair N S | 1998 | J S E ASCE1998,124,2: | 1 |
| 20 | Inelastic torsion of steel I-beams显示文摘 | Pi Y L Trahair N S | 1995 | Journal of Structural Engineering ASCE1995,121,4: | 1 |